I-Ribavirin: umuthi wesifo sokusha kwesibindi kohlobo C
-Delile
I-Ribavirin yinto okuthi uma ihlotshaniswa namanye amakhambi athile, njenge-alpha interferon, ikhonjiswe ekwelapheni i-hepatitis C.
Lo muthi kufanele usetshenziswe kuphela uma unconywa udokotela futhi ungathengwa kuphela lapho kwethulwa incwadi kadokotela.
Yenzelwe ini
I-Ribavirin ikhonjisiwe ekwelapheni i-hepatitis C engalapheki kubantu abadala nasezinganeni ezineminyaka engaphezu kwengu-3, ngokuhlanganiswa nezinye izidakamizwa zesifo, futhi akufanele isetshenziswe yodwa.
Funda ukuthi ungazibona kanjani izimpawu zesifo sokusha kwesibindi kohlobo C.
Ungathatha kanjani
Umthamo onconywayo uyehluka kuye ngeminyaka, isisindo somuntu kanye nomuthi osetshenziswe kanye ne-ribavirin. Ngakho-ke, umthamo kufanele uhlale uqondiswa yi-hepatologist.
Uma kungenasincomo esithile, imihlahlandlela ejwayelekile ikhombisa:
- Abantu abadala abangaphansi kwama-75 kg: umthamo wansuku zonke ka-1000 mg (amaphilisi ama-5 ka-200 mg) ngosuku, ahlukaniswe ngamanani ama-2;
- Abantu abadala abangaphezu kwama-75 kg: umthamo we-1200 mg (amaphilisi ayi-6 we-200 mg) ngosuku, ahlukaniswe ngemithamo emi-2.
Endabeni yezingane, isilinganiso kufanele ngaso sonke isikhathi sibalwe ngudokotela wezingane, futhi isilinganiso esinconyiwe sansuku zonke singu-10 mg / kg wesisindo somzimba.
Imiphumela emibi engaba khona
Eminye yemiphumela emibi kakhulu engahle yenzeke ngenkathi welashwa nge-ribavirin yi-anemia, i-anorexia, ingcindezi, ukuqwasha, ikhanda, isiyezi, ukwehla kokuhlushwa, ukuphefumula kanzima, ukukhwehlela, isifo sohudo, isicanucanu, ubuhlungu besisu, ukulahleka kwezinwele, i-dermatitis, ukulunywa, ukoma isikhumba, imisipha nobuhlungu obuhlangene, imfiva, ukugodola, ubuhlungu, ukukhathala, ukusabela endaweni yomjovo nokucasuka.
Ubani okungafanele athathe
I-Ribavirin iyaphikiswa kubantu abane-hypersensitivity to ribavirin noma kunoma yikuphi okuncishisiwe, ngenkathi ibele, kubantu abanomlando wangaphambilini wesifo senhliziyo esibi, kufaka phakathi isifo senhliziyo esingazinzile noma esingalawuleki, ezinyangeni eziyisithupha ezedlule, abantu abanokungasebenzi kahle okunesibindi noma okuncishisiwe i-cirrhosis ne-hemoglobinopathies.
Ukuqaliswa kokwelashwa kwe-interferon kuyaphikiswa ezigulini ezitheleleke nge-hepatitis C ne-HIV, ne-cirrhosis kanye ne-Child-Pugh score score 6.
Ngaphezu kwalokho, lesi sidakamizwa akufanele futhi sisetshenziswe ngabesifazane abakhulelwe futhi kufanele siqale ngemuva kokuthola imiphumela emibi esivivinyweni sokukhulelwa esenziwa ngokushesha ngaphambi kokuqala kokwelashwa.