I-Serotonin: Okudingeka Ukwazi

-Delile

• Yenzani i-serotonin?
• I-Serotonin nempilo yengqondo
• Amabanga ajwayelekile wamazinga we-serotonin
• Ungakwelapha kanjani ukuntuleka kwe-serotonin
• Ama-SSRIs
• Izikhuthazi zemvelo ze-serotonin
• Mayelana ne-serotonin syndrome
• Okubalulekile

Sifaka imikhiqizo esicabanga ukuthi ilusizo kubafundi bethu. Uma uthenga ngezixhumanisi ezikuleli khasi, singathola ikhomishini encane. Nansi inqubo yethu.

Yini i-serotonin?

ISerotonin iyiseli lamakhemikhali ezinzwa ezikhiqiza. Ithumela amasiginali phakathi kwamangqamuzana akho ezinzwa. I-Serotonin itholakala kakhulu ohlelweni lokugaya ukudla, yize kunjalo nakuma-platelet egazi nakuyo yonke imizwa yezinzwa.

ISerotonin yenziwa nge-amino acid tryptophan ebalulekile. Le amino acid kufanele ingene emzimbeni wakho ngokudla kwakho futhi itholakala kakhulu ekudleni okufana namantongomane, ushizi nenyama ebomvu. Ukushoda kwe-Tryptophan kungaholela emazingeni aphansi e-serotonin. Lokhu kungaholela ekuphazamisekeni kwemizwelo, njengokukhathazeka noma ukudangala.

Yenzani i-serotonin?

I-Serotonin ithinta zonke izingxenye zomzimba wakho, kusukela kwimizwelo yakho kuya kumakhono akho emoto. I-Serotonin ibhekwa njengesiqinisi semvelo semvelo. Yikhemikhali esiza ngokulala, ukudla nokugaya. ISerotonin nayo iyasiza:

• ukunciphisa ukudangala
• lawula ukukhathazeka
• pholisa amanxeba
• vusa isicanucanu
• gcina impilo yethambo

Nakhu ukuthi i-serotonin isebenza kanjani emisebenzini ehlukahlukene emzimbeni wakho wonke:

Ukuhamba kwamathumbu: I-Serotonin itholakala ikakhulu esiswini nasemathunjini omzimba. Kuyasiza ukulawula ukuhamba kwamathumbu nokusebenza kwakho.

Isimo: I-Serotonin ebuchosheni kucatshangwa ukuthi ilawula ukukhathazeka, injabulo, nomoya. Amazinga aphansi amakhemikhali ahlotshaniswa nokudangala, futhi amazinga anyukayo e-serotonin alethwa yimithi kucatshangwa ukuthi anciphisa ukuvuka.

Isicanucanu: ISerotonin iyingxenye yesizathu esenza ube nesicanucanu. Ukukhiqizwa kwe-serotonin kuphakama ukukhipha ukudla okuyingozi noma okuphazamisayo ngokushesha kuhudo. Ikhemikhali nalo liyanda egazini, eligqugquzela ingxenye yobuchopho elawula isicanucanu.

Ukulala: Leli khemikhali libhekele ukuvuselela izingxenye zobuchopho ezilawula ukulala nokuvuka. Ukuthi ulala noma uvukile kuncike ekutheni iyiphi indawo evuselelwayo nokuthi iyiphi i-serotonin receptor esetshenziswayo.

Ukujiya kwegazi: Ama-platelet egazi akhipha i-serotonin ukusiza ukupholisa amanxeba. I-serotonin ibangela imithambo emincane ukuba inciphe, isize ukwakha amahlule egazi.

Impilo yamathambo: I-Serotonin ibamba iqhaza empilweni yethambo. Izinga eliphakeme kakhulu le-serotonin emathanjeni lingaholela ekuthambekeleni kwamathambo, okwenza amathambo abe ntekenteke.

Umsebenzi wezocansi: Amazinga aphansi e-serotonin ahlotshaniswa nokwanda kwe-libido, kuyilapho amazinga e-serotonin akhuphukile ahlotshaniswa ne-libido encishisiwe.

I-Serotonin nempilo yengqondo

I-Serotonin isiza ukulawula imizwa yakho ngokwemvelo. Lapho amazinga akho e-serotonin ejwayelekile, uzizwa:

• ngijabule ngokwengeziwe
• ukuzola
• kugxile kakhudlwana
• ukukhathazeka kancane
• uzinze ngokwengeziwe ngokomzwelo

Ucwaningo lwango-2007 lwathola ukuthi abantu abanokucindezeleka bavame ukuba namazinga aphansi e-serotonin. Ukuntuleka kwe-Serotonin nakho kuye kwaxhunyaniswa nokukhathazeka nokuqwasha.

Ukungaboni ngaso linye okuncane mayelana nendima edlalwa yi-serotonin empilweni yengqondo kwenzeke. Abanye abacwaningi babuze ukuthi ukwanda noma ukwehla kwe-serotonin kungathinta yini ukucindezeleka. Ucwaningo olusha luthi luyakwenza. Isibonelo, i-2016 yahlola amagundane entula ama-serotonin autoreceptors avimbela uketshezi lwe-serotonin. Ngaphandle kwala ma-autoreceptors, amagundane ayenamazinga aphezulu we-serotonin atholakala ebuchosheni bawo. Abaphenyi bathole ukuthi la magundane akhombisa ukukhathazeka okuncane nokuziphatha okuhlobene nokudana.

Amabanga ajwayelekile wamazinga we-serotonin

Ngokuvamile, uhla olujwayelekile lwamazinga we-serotonin egazini lakho angama-nanograms ayi-101-283 ngemililitha ngayinye (ng / mL). Lokhu kulinganiswa, noma kunjalo, kungahluka kancane ngokuya ngezilinganiso namasampuli ahloliwe, ngakho-ke khuluma nodokotela wakho ngemiphumela ethile yokuhlolwa.

Amazinga aphezulu e-serotonin angaba uphawu lwe-carcinoid syndrome. Lokhu kufaka iqembu lezimpawu ezihlobene nezicubu ze:

• amathumbu amancane
• isithasiselo
• ikholoni
• amashubhu we-bronchial

Udokotela uzothatha ukuhlolwa kwegazi ukukala amazinga e-serotonin egazini lakho ukuthola isifo noma ukusilawula.

Ungakwelapha kanjani ukuntuleka kwe-serotonin

Ungenyusa amazinga akho e-serotonin ngemithi nangezinye izinketho zemvelo.

Ama-SSRIs

Amazinga aphansi e-serotonin ebuchosheni angadala ukucindezeleka, ukukhathazeka, nenkinga yokulala. Odokotela abaningi bazonikeza i-serotonin reuptake inhibitor (SSRI) ekhethiwe yokwelapha ukucindezeleka. Bayihlobo elinqunyelwe kakhulu le-antidepressant.

Ama-SSRI akhulisa amazinga e-serotonin ebuchosheni ngokuvimba ukubuyiselwa kwamakhemikhali, ngakho-ke amanye ahlala esebenza. Ama-SSRI afaka phakathi iProzac neZoloft, phakathi kokunye.

Uma uthatha izidakamizwa ze-serotonin, akufanele usebenzise eminye imithi ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuxuba izidakamizwa kungakubeka engcupheni ye-serotonin syndrome.

Izikhuthazi zemvelo ze-serotonin

Ngaphandle kwama-SSRI, lezi zinto ezilandelayo zingakhuphula amazinga e-serotonin, ngokusho kwephepha elishicilelwe ku:

• Ukuvezwa ekukhanyeni okukhanyayo: Ukushiswa yilanga noma ukwelashwa okukhanyayo kuyizindlela zokwelashwa ezivame ukunconywa zokwelapha ukudangala kwesizini. Thola ukukhetha okuhle kwemikhiqizo yokwelapha elula lapha.
• Ukuzivocavoca umzimba: Ukuvivinya umzimba njalo kungaba nemiphumela yokuqinisa imizwa.
• Ukudla okunempilo: Ukudla okungakhuphula amazinga e-serotonin kufaka amaqanda, ushizi, ama-turkey, amantongomane, i-salmon, i-tofu, no-phayinaphu.
• Ukuzindla: Ukuzindla kungasiza ekunciphiseni ukucindezeleka futhi kuthuthukise umbono omuhle ngempilo, ongakhuphula kakhulu amazinga e-serotonin.

Mayelana ne-serotonin syndrome

Izidakamizwa ezenza amazinga akho e-serotonin akhuphuke futhi aqoqe emzimbeni wakho angaholela ku-serotonin syndrome. Lesi sifo singavela ngemuva kokuqala ukusebenzisa umuthi omusha noma ukwandisa umthamo wemithi ekhona.

Izimpawu ze-serotonin syndrome zifaka:

• ngiqhaqhazela
• isifo sohudo
• ikhanda
• ukudideka
• abafundi abahlanzekile
• uhlevane

Izimpawu ezinzima zingafaka:

• imisipha eshwibayo
• ukulahleka kokuqina kwemisipha
• ukuqina kwemisipha
• umkhuhlane omkhulu
• ukushaya kwenhliziyo okusheshayo
• umfutho wegazi ophakeme
• ukushaya kwenhliziyo okungajwayelekile
• isithuthwane

Azikho izivivinyo ezingathola isifo se-serotonin. Esikhundleni salokho, udokotela wakho uzokwenza ukuhlolwa ngokomzimba ukuthola ukuthi unayo yini.

Imvamisa, izimpawu ze-serotonin syndrome ziyonyamalala kungakapheli usuku uma uthatha umuthi ovimba i-serotonin noma ushintshe umuthi obanga isimo kwasekuqaleni.

I-Serotonin syndrome ingasongela impilo uma ishiywe ingalashwa.

Okubalulekile

I-Serotonin ithinta zonke izingxenye zomzimba wakho. Inesibopho semisebenzi eminingi ebalulekile esithola osukwini. Uma amazinga akho engekho ebhalansi, angathinta inhlalakahle yakho engqondweni, ngokomzimba nangokomzwelo. Kwesinye isikhathi, ukungalingani kwe-serotonin kungasho into ebucayi kakhulu. Kubalulekile ukunaka umzimba wakho futhi ukhulume nodokotela wakho nganoma yikuphi ukukhathazeka.