Izimpawu zesifo sikaCushing's syndrome, izimbangela kanye nokwelashwa

-Delile

• Izimpawu eziyinhloko
• Izimbangela zesifo sikaCushing
• Ukuxilongwa kwenziwa kanjani
• Yelashwa kanjani
• Izinkinga ezingenzeka

I-Cushing's syndrome, ebizwa nangokuthi isifo sikaCushing noma i-hypercortisolism, inguquko yamahomoni ebonakala ngokwanda kwamazinga e-hormone i-cortisol egazini, okuholela ekubonakaleni kwezimpawu zesifo ezifana nokuthola isisindo esisheshayo kanye nokuqoqana kwamafutha emzimbeni. indawo yesisu nobuso, ngaphezu kokuthuthuka kwemifudlana ebomvu emzimbeni nesikhumba esinamafutha esithanda umqubuko, isibonelo.

Ngakho-ke, lapho kukhona lezi zimpawu nezimpawu, kunconywa ukuthi uthintane nodokotela we-endocrinologist ukuze kukhonjiswe ukuhlolwa kwegazi nemifanekiso futhi, ngalokho-ke, ukwelashwa okufanele kakhulu kungakhonjiswa, okungenziwa ngokusebenzisa umuthi noma ukuhlinzwa, Ngokwesibonelo.

Izimpawu eziyinhloko

Uphawu oluphawuleka kakhulu lwe-Cushing's syndrome ukunqwabelana kwamafutha kuphela esifundeni sesisu nasebusweni, esaziwa nangokuthi ubuso benyanga egcwele. Ngaphezu kwalokho, ezinye izimpawu nezimpawu ezingahle zihlobane nalesi sifo yilezi:

• Ukuthola isisindo ngokushesha, kepha izingalo nemilenze emincane;
• Ukubukeka kwemisila ebanzi, ebomvu esiswini;
• Ukubukeka kwezinwele ebusweni, ikakhulukazi kwabesifazane;
• Ingcindezi eyengeziwe;
• Isifo sikashukela, ngoba kujwayelekile ukuthi kunoshukela osezingeni eliphakeme egazini;
• Ukwehla kwe-libido nokuzala;
• Umjikelezo wokuya esikhathini ngokungajwayelekile;
• Ubuthakathaka bemisipha;
• Isikhumba esinamafutha nezinduna;
• Kunzima ekupholiseni amanxeba;
• Ukuvela kwamabala ansomi.

Imvamisa kuqashelwa ukuvela kwezimpawu eziningana ngasikhathi sinye futhi kuvame kakhulu kwiziguli ezinezifo ezifana nesifo samathambo, i-asthma, i-lupus noma ngemuva kokufakelwa kwezitho zomzimba futhi ezithatha i-corticosteroids izinyanga ezimbalwa ngamanani aphezulu. Endabeni yezingane ezine-Cushing's syndrome, ukukhula kancane, nokuphakama okuphansi, izinwele zobuso nezomzimba ezikhulayo kanye nempandla kungabonakala.

Izimbangela zesifo sikaCushing

I-syndrome yenzeka ngenxa yokwanda kwamazinga e-cortisol egazini, engenzeka ngenxa yezimo eziningana. Imbangela ejwayelekile yalokhu kwanda futhi ethanda ukuthuthukiswa kwesifo ukusetshenziswa isikhathi eside futhi ngemithamo ephezulu yama-corticosteroids, okuvame ukukhonjiswa ekwelapheni izifo ezifana ne-lupus, i-rheumatoid arthritis ne-asthma, ngaphezu kwalokho okukhonjisiwe abantu asebevele befakelwe izitho.

Ngaphezu kwalokho, i-Cushing's syndrome ingenzeka ngenxa yokuba khona kwe-timor ku-pituitary gland, etholakala ebuchosheni, okuholela ekwehlisweni komthetho ekukhiqizeni i-ACTH futhi, ngenxa yalokho, ukwanda komkhiqizo we-cortisol, ongatholwa ekugxileni okuphezulu egazini. Yazi ukuthi i-hormone i-cortisol yenzelwe ini.

Ukuxilongwa kwenziwa kanjani

Ukuxilongwa kwe-Cushing's syndrome kufanele kwenziwe ngudokotela we-endocrinologist ngokuya ngokuhlolwa kwezimpawu nezimpawu ezethulwe ngumuntu, umlando wezempilo kanye nokuhlolwa kwelabhorethri noma kwe-imaging.

Ngakho-ke, kunganconywa udokotela ukuthi enze ukuhlolwa kwamahora angama-24 kwegazi, amathe nomchamo ukuhlola amazinga e-cortisol ne-ACTH ajikeleza emzimbeni. Ngaphezu kwalokho, kunganconywa ukuhlolwa kokukhuthaza nge-dexamethasone, okuwumuthi ovuselela ukusebenza kwendlala ye-pituitary futhi, ngalokho, kungasiza ukuxilongwa. Ngenxa yokusetshenziswa kwe-dexamethasone, kunganconywa ukuthi lowo muntu angeniswe esibhedlela cishe izinsuku ezimbili.

Ukuze uhlole ubukhona besimila endlaleni ye-pituitary, udokotela angacela ukusebenza kwe-computed tomography noma i-magnetic resonance imaging, ngokwesibonelo. Ezimweni eziningi, kuyadingeka ukuphinda izivivinyo ukuqinisekisa ukuxilongwa bese uqala ukwelashwa okulungile, njengoba ezinye izimpawu zivamile kwezinye izifo, ezingenza ukuxilongwa kube nzima.

Yelashwa kanjani

Ukwelashwa kwe-Cushing's syndrome kufanele kuqondiswe yi-endocrinologist futhi kuyahluka kuye ngesizathu se-syndrome. Lapho lesi sifo sibangelwa ukusetshenziswa isikhathi eside kwama-corticosteroids, ukwehla komthamo womuthi kuboniswa, ngokuyalelwa ngudokotela futhi, uma kungenzeka, ukumiswa kwaso.

Ngakolunye uhlangothi, lapho uCushing's syndrome ebangelwa isimila, ukwelashwa kuvame ukufaka ukuhlinzwa ukuze kususwe isimila bese kwenziwa i-radiotherapy noma i-chemotherapy. Ngaphezu kwalokho, ngaphambi kokuhlinzwa noma lapho isimila singeke sisuswe, udokotela angancoma ukuthi isiguli siphuze imithi yokulawula ukukhiqizwa kwe-cortisol.

Ukunciphisa izimpawu zesifo kubalulekile ukugcina ukudla okungenawo usawoti kanye noshukela futhi udle izithelo nemifino nsuku zonke ngoba kungukudla okunothe amavithamini namaminerali futhi okusiza ukuqinisa amasosha omzimba.

Izinkinga ezingenzeka

Lapho ukwelashwa kwe-Cushing's syndrome kungenziwa ngendlela efanele, kungenzeka ukuthi kube nokuhluleka kokulawula kwamahomoni okungabeka impilo yomuntu engcupheni. Lokho kungenxa yokuthi amazinga ama-hormone angalingani angadala ukungasebenzi kahle kwezinso nokuhluleka komzimba.