Iserotonin syndrome: kuyini, izimpawu, izimbangela kanye nokwelashwa

-Delile

• Ziyini izimpawu
• Izimbangela ezingaba khona
• Imithi ekhulisa i-serotonin emzimbeni
• Yelashwa kanjani

Iserotonin syndrome iqukethe ukwanda komsebenzi we-serotonin ohlelweni oluphakathi lwezinzwa, olubangelwa ukusetshenziswa okungafanele kwemithi ethile, engathinta ubuchopho, imisipha nezitho zomzimba, okungaholela ekufeni.

ISerotonin iyi-neurotransmitter esebenza ebuchosheni, ebalulekile ekusebenzeni kahle komzimba, ngoba ilawula imizwa, ukulala, ukudla, ukushaya kwenhliziyo, ukushisa komzimba nokusebenza kwengqondo. Kodwa-ke, imithamo ephezulu ye-serotonin ingahlehlisa ukusebenza komzimba futhi iholele ekubonakaleni kwezimpawu ezinzima. Bona imisebenzi eminingi ye-serotonin.

Ukwelashwa kwe-serotonin syndrome kufanele kwenziwe esibhedlela, ngokushesha okukhulu, ngokusebenzisa i-serum emthanjeni, ukumiswa komuthi obangele inkinga nokusetshenziswa kwezidakamizwa ukuqeda izimpawu.

Ziyini izimpawu

Ukukhathazeka, ukucasuka, ukuqubuka kwemisipha, ukudideka kanye nemibono, ukuqhaqhazela nokugodola, isicanucanu kanye nohudo, ukukhuphuka kwengcindezi yegazi nokushaya kwenhliziyo, ukukhathazeka okuthe xaxa, abafundi abahluziwe, yizimpawu ezivame kakhulu.

Ezimweni ezinzima kakhulu futhi uma zingelashwa ngokuphuthumayo, i-serotonin syndrome ingadala izimpawu ezinzima kakhulu, njengokushaya kwenhliziyo okungajwayelekile, ukulahlekelwa ukwazi, ukuxhuzula, ikhoma nokufa.

Izimbangela ezingaba khona

Iserotonin syndrome ibangelwa ukusetshenziswa okungafanele kwezidakamizwa ezandisa amazinga e-serotonin emzimbeni. Ngakho-ke, ukukhulisa isilinganiso semithi ekhulisa i-serotonin, ukuhlanganiswa kwalezi zidakamizwa nezinye ezithuthukisa ukusebenza kwazo, noma ukusetshenziswa kwalezi zidakamizwa ngasikhathi sinye nezidakamizwa, kungaholela ekutholakaleni kwalesi sifo.

Imithi ekhulisa i-serotonin emzimbeni

Eminye yezidakamizwa ezandisa i-serotonin emzimbeni yilezi:

• Izidambisi, njenge-imipramine, i-clomipramine, i-amitriptyline, i-nortriptyline, i-fluoxetine, i-paroxetine, i-citalopram, i-sertraline, i-fluvoxamine, i-venlafaxine, i-duloxetine, i-nefazodone, i-trazodone, i-bupropion, i-mirtazapine, i-tranylcypemine ne-moclobine;
• Izixazululo ze-Migraine iqembu lama-triptan, njenge-zolmitriptan, i-naratriptan noma i-sumatriptan, isibonelo;
• Amakhambi Okwehlela equkethe i-dextromethorphan, okuyisithako esisebenza ohlelweni lwezinzwa oluphakathi ukuvimbela ukukhwehlela;
• Ama-opioid esetshenziselwa ukwelapha ubuhlungu, njenge-codeine, i-morphine, i-fentanyl, i-meperidine ne-tramadol, isibonelo;
• Izindlela zokwelapha isicanucanu nokuhlanza, njenge-metoclopramide ne-ondansetron;
• Ama-anticonvulsants, njenge-sodium valproate ne-carbamazepine;
• Ama-antibiotic, ama-antifungal kanye nama-antivirals, njenge-erythromycin, i-ciprofloxacin, i-fluconazole ne-ritonavir;
• Izidakamizwa ezingekho emthethweni, njenge-cocaine, ama-amphetamine, i-LSD kanye ne-ecstasy.

Ngaphezu kwalokho, ezinye izithako zemvelo, ezifana ne-tryptophan, iSt John's wort (iSt.

Yelashwa kanjani

Ukwelashwa kwe-serotonin syndrome kuncike ebukhulwini bezimpawu. Ezimweni ezilinganiselayo kuya kwezinzima, kufanele kwenziwe ngokushesha okukhulu, esibhedlela, lapho umuntu egadiwe khona futhi angathola i-serum emthanjeni kanye nemithi yokwelapha izimpawu, ezinjengomkhuhlane, ukuphazamiseka nokuqaqamba kwemisipha, ngokwesibonelo. Ezimweni ezinzima kakhulu, kungadingeka ukuthatha imishanguzo evimba isenzo se-serotonin.

Ngaphezu kwalokho, umuthi owuthathayo umuntu kufanele ubuyekezwe futhi ulungiswe udokotela, kanye nemithamo ebekiwe.