Isikhathi se-Prothrombin: kuyini, kwenzelwa ini namanani

-Delile

• Amanani ayizethenjwa
• Incazelo yemiphumela
• Isikhathi esiphezulu se-prothrombin
• Isikhathi esiphansi se-prothrombin

Isikhathi seProthrombin noma i-PT ukuhlolwa kwegazi okuhlola ikhono legazi lokuvala, okungukuthi, isikhathi esidingekayo sokumisa ukopha, ngokwesibonelo.

Ngakho-ke, isivivinyo sesikhathi se-prothrombin sisetshenziswa noma nini lapho kuphuma njalo igazi noma ukulinyazwa ukuzama ukuthola imbangela yenkinga, kanye nalapho kunezinsolo zezinkinga zesibindi, ukucelwa ukuthi ulinganise i-TGO, TGP ne-GGT, ngokwesibonelo. Bona ukuthi yiziphi izivivinyo ezihlola isibindi.

Endabeni yabantu abasebenzisa ama-anticoagulants omlomo, njenge-Warfarin noma i-Aspirin, udokotela ucela i-INR ngezikhathi ezithile, okuyisilinganiso esithile kakhulu kune-TP ukuhlola umphumela wezidakamizwa, ngoba i-TP ivame ukuba phezulu ngaphansi kwalezi zimo.

I-Prothrombin, eyaziwa nangokuthi i-coagulation factor II, iyiprotheni ekhiqizwa isibindi futhi lapho ivulwa ikhuthaza ukuguqulwa kwe-fibrinogen ibe yi-fibrin, yona, kanye nama-platelet, enza ungqimba oluvimbela ukopha. Ngakho-ke, i-prothrombin iyinto ebalulekile ekunqandeni kwegazi ukuthi kwenzeke.

Amanani ayizethenjwa

Inani lesethenjwa le- isikhathi se-prothrombin ngoba umuntu ophilile kufanele ahluke phakathi Imizuzwana eyi-10 nengu-14. Uma kwenzeka kuba INR, inani lesethenjwa lomuntu ophilile kufanele lehluke phakathi kuka-0.8 no-1.

Kodwa-ke, uma usebenzisa ama-anticoagulants omlomo, inani kufanele libe phakathi kuka-2 no-3, kuya ngesifo esiholele ekudingeni ukwelashwa ngalolu hlobo lomuthi.

Incazelo yemiphumela

Umphumela wokuhlolwa kwesikhathi se-prothrombin ungashintshwa ngenxa yezimbangela ezahlukahlukene, ngakho-ke noma nini lapho kuba nezinguquko, udokotela anga-oda ukuhlolwa okusha ukuze akwazi ukuthola imbangela efanele bese eqala ukwelashwa.

Ezinye zezimbangela ezivame kakhulu zifaka:

Isikhathi esiphezulu se-prothrombin

Lo mphumela ukhombisa ukuthi uma ukusika kwenzeka, ukopha kuzothatha isikhathi eside ukuyeka, futhi ezinye zezimbangela ezivame kakhulu zifaka:

• Ukusetshenziswa kwama-anticoagulants;
• Ukuguqulwa kwezitshalo zamathumbu;
• Ukudla okungalingani kahle;
• Isifo sesibindi;
• Ukushoda kukaVitamin K;
• Izinkinga ze-coagulation, njenge-hemophilia;

Ngaphezu kwalokho, eminye imishanguzo efana nama-antibiotic, i-corticosteroids kanye ne-diuretics nayo ingashintsha inani lohlolo, ngakho-ke kungakuhle ukuthi wazise udokotela ngayo yonke imithi oyisebenzisayo.

Isikhathi esiphansi se-prothrombin

Lapho inani le-prothrombin liphansi kusho ukuthi i-coagulation yenzeka ngokushesha okukhulu. Ngakho-ke, yize ukuphuma kwegazi kungavamile futhi kuyeka ngokushesha, kunengozi eyengeziwe yamahlule angaholela ekungenweni yisifo noma kohlangothi.

Ezinye zezimbangela ezingadala lolu shintsho zifaka:

• Ukusetshenziswa kwezithasiselo zikavithamini K;
• Ukusetshenziswa ngokweqile kokudla okune-vitamin K, njengesipinashi, i-broccoli noma isibindi;
• Ukusetshenziswa kwamaphilisi e-estrogen njengephilisi lokulawula ukuzalwa.

Kulezi zimo, kungadingeka ukuqala ukusebenzisa ama-anticoagulants noma imijovo ye-heparin kuze kutholakale imbangela yenguquko. Ngemuva kwalokho, udokotela uzoncoma ukwelashwa okufanele kakhulu.