Ngabe iVitamin D inganciphisa ubungozi bakho be-COVID-19?

-Delile

• Uvithamini D uyithinta kanjani impilo yomzimba?
• Ingabe ukuthatha uvithamini D kungavikela i-COVID-19?
• Okubalulekile

UVitamin D uvithamini oncibilika njengamafutha odlala izindima eziningi ezibalulekile emzimbeni wakho.

Lesi sithako sibaluleke kakhulu empilweni yesistimu yomzimba, okushiya abantu abaningi bezibuza ukuthi ukwengeza nge-vitamin D kungasiza yini ukunciphisa ubungozi bokuthola i-coronavirus entsha edala i-COVID-19.

Ngenkathi okwamanje lingekho ikhambi le-COVID-19, izindlela zokuzivikela njengokujija komzimba kanye nenhlanzeko efanele zingakuvikela ekutholeni igciwane.

Futhi, olunye ucwaningo lukhombisa ukuthi ukuba namazinga anempilo kavithamini D kungasiza ekugcineni amasosha akho omzimba enempilo futhi kungavikela ezifweni zokuphefumula ngokujwayelekile.

Ucwaningo lwakamuva lukhombise ukuthi iziguli ezibhedlela nge-COVID-19 ezinamazinga anele kavithamini D abe nengozi enciphile yemiphumela emibi nokufa ().

Lo mbhalo uchaza ukuthi uvithamini D uyithinta kanjani impilo yomzimba nokuthi ukwengeza ngalesi sakhi kungasiza ekuvikeleni ezimeni zokuphefumula.

Uvithamini D uyithinta kanjani impilo yomzimba?

Uvithamini D uyadingeka ekusebenzeni kahle kwesistimu yakho yokuzivikela - okuwumugqa wokuqala womzimba wakho wokuzivikela ezifweni nasezifweni.

Le vithamini ibamba iqhaza elibalulekile ekukhuthazeni ukuphendula komzimba. Inezinto ezimbili ezilwa nokuvuvukala nezokugomela, futhi ibalulekile ekwenzeni kusebenze izivikeli mzimba ().

UVitamin D waziwa ngokuthuthukisa ukusebenza kwamaseli omzimba, kufaka phakathi ama-T cell nama-macrophages, avikela umzimba wakho kuma-pathogen ().

Eqinisweni, uvithamini ubaluleke kakhulu ekusebenzeni komzimba ukuthi amazinga aphansi kavithamini D ahlotshaniswe nokwanda kokutheleleka ekungenweni yizifo, izifo kanye nokuphazamiseka okuhlobene nomzimba ().

Isibonelo, amazinga aphansi kavithamini D ahlotshaniswa nengozi eyandayo yezifo zokuphefumula, kufaka phakathi isifo sofuba, i-asthma, nesifo esingapheliyo se-pulmonary disease (COPD), kanye nezifo zokuphefumula ngegciwane kanye namagciwane (,,,).

Ngaphezu kwalokho, ukushoda kukavithamini D kuye kwaxhunyaniswa nokwehla komsebenzi wamaphaphu, okungathinta amandla omzimba wakho wokulwa nezifo zokuphefumula (,).

Uvithamini D ubalulekile ekusebenzeni komzimba. Ukuntuleka kwalesi sakhi kunganciphisa ukuphendula komzimba futhi kwandise ubungozi bokutheleleka nezifo.

Ingabe ukuthatha uvithamini D kungavikela i-COVID-19?

Njengamanje, alikho ikhambi noma ukwelashwa kwe-COVID-19, futhi zimbalwa izifundo ezenze uphenyo ngemiphumela yokwengezwa kukavithamini D noma ukushoda kukavithamini D engcupheni yokuthola i-coronavirus entsha, i-SARS-CoV-2.

Kodwa-ke, ucwaningo lwakamuva luthole ukuthi izinga legazi le-25-hydroxyvitamin D okungenani lama-30 ng / mL libonakala lisiza ukunciphisa amathuba emiphumela emibi yomtholampilo nokufa ezigulini ezibhedlela ezine-COVID-19.

Idatha yesibhedlela yeziguli ezingama-235 ezine-COVID-19 yahlaziywa.

Ezigulini ezindala kuneminyaka engama-40, labo ababenamazinga anele kavithamini D babenamathuba amancane okuba nemiphumela emibi engu-51.5%, kufaka phakathi ukungazi lutho, i-hypoxia, nokufa, uma kuqhathaniswa neziguli ezinamavithamini D. ().

Noma kunjalo, ezinye izifundo zikhombisile ukuthi ukushoda kukavithamini D kungalimaza ukusebenza kwamasosha omzimba futhi kwandise amathuba okuba nezifo zokuphefumula ().

Ngokwengeziwe, ezinye izifundo zikhombisile ukuthi izengezo zikavithamini D zingathuthukisa ukuphendula komzimba futhi zivikele ezifweni zokuphefumula ngokuphelele.

Ukubuyekezwa kwakamuva okubandakanya abantu abayi-11,321 abavela emazweni ayi-14 kukhombisile ukuthi ukwengeza nge-vitamin D kwehlise ubungozi bokutheleleka okuphefumulayo (i-ARI) kubo bobabili ababenamazinga kavithamini D anele futhi anele.

Kukonke, ucwaningo lukhombisile ukuthi izithasiselo zikavithamini D zinciphise ubungozi bokuthola okungenani i-ARI eyodwa ngo-12%. Umphumela wokuvikela wawunamandla kakhulu kulabo abanamazinga aphansi kavithamini D ().

Ngaphezu kwalokho, ukubuyekezwa kwathola ukuthi izengezo zikavithamini D zazisebenza kakhulu ekuvikeleni i-ARI lapho zithathwa nsuku zonke noma ngeviki ngemithamo emincane futhi zingasebenzi kahle uma zithathwa ngemithamo emikhulu, enezikhala eziningi ().

Izithasiselo zikaVitamin D nazo zikhonjisiwe ukunciphisa ukufa kwabantu abadala asebekhulile, abasengozini enkulu yokuthola izifo zokuphefumula njenge-COVID-19 ().

Ngaphezu kwalokho, ukushoda kukavithamini D kuyaziwa ukuthuthukisa inqubo eyaziwa ngokuthi "isivunguvungu se-cytokine" ().

Ama-cytokines angamaprotheni ayingxenye ebalulekile yesistimu yomzimba. Zingaba nemiphumela yokuvuvukala kanye nokulwa nokuvuvukala futhi zidlale izindima ezibalulekile, zisize ukuvikela ekuthelelekeni nasezifweni (,).

Kodwa-ke, ama-cytokines nawo angadala ukulimala kwezicubu ngaphansi kwezimo ezithile.

Isiphepho se-cytokine sibhekisa ekukhishweni okungalawuleki kwama-cytokines ahlasela ukuvuvukala okwenzeka ekuphenduleni ukutheleleka noma ezinye izinto. Lokhu kukhishwa okungalawuleki kahle nokwedlulele kwama-cytokines kuholela ekulimaleni kakhulu kwezicubu futhi kuthuthukise ukuqhubekela phambili kwezifo nobukhali ().

Eqinisweni, kuyimbangela enkulu yokwehluleka kwezitho eziningi kanye ne-acute yokuphefumula (i-ARDS), kanye nesici esibalulekile ekuqhubekeni nasekuqineni kwe-COVID-19 ().

Isibonelo, iziguli ezinamacala abucayi e-COVID-19 zikhonjisiwe ukuthi zikhipha inani elikhulu lama-cytokines, ikakhulukazi i-interleukin-1 (IL-1) ne-interleukin-6 (IL-6) ().

Ukushoda kukavithamini D kuhlotshaniswe nokuncipha kokuzivikela komzimba futhi kungathuthukisa isivunguvungu se-cytokine.

Kanjalo, abacwaningi bathi ukungabi khona kukavithamini D kungakhuphula ubungozi bezinkinga ezinzima ze-COVID-19, kanye nokuthi ukwengezelwa kukavithamini D kunganciphisa izinkinga ezihlobene neziphepho ze-cytokine nokuvuvukala okungalawuleki kubantu abane-COVID-19 (, 21).

Njengamanje, izivivinyo eziningi zemitholampilo ziphenya ngemiphumela yokwengeza kwe-vitamin D (kumithamo efinyelela ku-200,000 IU) kubantu abane-COVID-19 (, 22).

Yize ucwaningo kule ndawo luqhubeka, kubalulekile ukuqonda ukuthi ukuthatha i-vitamin D eyengeziwe akukwazi ukukuvikela ekuthuthukiseni i-COVID-19.

Kodwa-ke, ukuntula uvithamini D kungakhuphula ukuthambekela kwakho ekuthelelekeni nasezifweni ngokulimaza ukusebenza komzimba.

Lokhu kuyakhathaza kakhulu ngoba abantu abaningi abanayo i-vitamin D, ikakhulukazi abantu asebekhulile abasengozini yokuthola izinkinga ezinkulu ezihlobene ne-COVID-19 ().

Ngalezi zizathu, kuwumqondo omuhle ukuthi umhlinzeki wakho wezokunakekelwa kwempilo ahlole amazinga akho kavithamini D ukuthola ukuthi unakho yini ukushoda kulesi sakhi somzimba esibalulekile. Lokhu kubaluleke kakhulu phakathi nezinyanga zasebusika.

Ngokuya ngamazinga akho egazi, ukwengeza nge-1,000-4,000 IU kavithamini D ngosuku kuvame ukubanela abantu abaningi. Kodwa-ke, labo abanamazinga aphansi egazi bazodinga imithamo ephakeme kakhulu ukukhuphula amazinga abo ebangeni elifanele ().

Yize izincomo zokuthi yiliphi izinga levithamini D elilungile ziyahlukahluka, ochwepheshe abaningi bayavuma ukuthi amazinga kavithamini D alungile aphakathi kuka-30-60 ng / mL (75-150 nmol / L) (,).

Yize ucwaningo luqhubeka, ubufakazi bokuthi izengezo zikavithamini D zinciphisa ubungozi bokusungula i-COVID-19 namanje. Ukuba namazinga kavithamini D anempilo kungathuthukisa impilo yomzimba futhi kungasiza kubantu abane-COVID-19.

Okubalulekile

UVitamin D udlala izindima eziningi ezibalulekile emzimbeni wakho, kufaka phakathi ukukhuthaza impilo yamasosha akho omzimba.

Ucwaningo lwesayensi luphakamisa ukuthi ukwengeza nge-vitamin D kungavikela ezifweni zokuphefumula, ikakhulukazi kulabo abangenayo i-vitamin.

Ucwaningo lwamuva lukhombisa ukuthi amazinga e-vitamin D anele angasiza abantu abane-COVID-19 ukuthi bagweme imiphumela emibi.

Noma kunjalo, asazi noma ukuthatha izithasiselo zikavithamini D kunciphisa ubungozi bakho bokuthola i-COVID-19 ngenxa yokuthola i-coronavirus.

Khuluma nodokotela wakho mayelana nokwengeza nge-vitamin D ukukhulisa impendulo yakho yomzimba jikelele.