Kungani Ngenze Ukuhlolelwa Ufuzo Umdlavuza Webele

-Delile

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"Imiphumela yakho isilungile."

Ngaphandle kwamagama athusayo, i-imeyili eyenziwe kahle ibukeka ihlokoma. Akubalulekile.

Kepha sekuzongitshela ukuthi ngabe ngingumuntu othwala i-BRCA1 noma i-BRAC2 gene mutation, ezoshayela ingozi yami yokuthola umdlavuza webele nowamaqanda ophahleni. Cishe ukungitshela ukuthi kuzodingeka ngibheke ukuthi kungenzeka yini ukuthi kube nokuvinjelwa kwe-mastectomy ephindwe kabili ebusweni ngosuku olulodwa. Ngempela, sekuzongitshela ukuthi izinqumo zami zezempilo zizobukeka kanjani kusukela kulo mzuzu kuqhubeke.

Angiqali ukuhlangana nomdlavuza webele. Nginomlando womndeni walesi sifo, ngakho ukuqwashisa kanye nemfundo kube yizingxenye ezinkulu zempilo yami yomuntu omdala. (Nakhu Okusebenza Ngempela Ukwehlisa Ingozi Yakho Yomdlavuza Webele.) Noma kunjalo, ngesikhathi inyanga Yokuqwashisa Ngomdlavuza Webele ifika ekupheleni njalo ngo-Okthoba, ngokuvamile ngisuke ngifinyelele umkhawulo wami wamaribhoni aphinki kanye ne-fundraiser engu-5Ks. Ngokuqondene nobuchwepheshe bokuhlolela izinhlobo zofuzo ze-BRCA? Ngangazi ukuthi ikhona, kodwa ngangingaqiniseki ngempela ukuthi ngenzenjani ngakho.

Ngabe sengizwa nge-Colour Genomics, inkampani yokuhlola izakhi zofuzo ehlola isampula yamathe ukuze kuguqulwe izakhi zofuzo eziyi-19 (okuhlanganisa i-BRCA1 ne-BRCA2). Kwakuyindlela elula, ngangazi ukuthi sekuyisikhathi sokuyeka ukugwema le nkinga bese ngiqala ukuthatha izinqumo ezinamandla mayelana nempilo yami. Ngiyanaka lokho okungena emzimbeni wami (funda: ngezikhathi ezithile kuphela ngiphuphuma kulolo cezu lwesibili lwe-pizza), kungani-ke ngingakunaki osekwenzeka vele? ngaphakathi umzimba wami?

Angisiye umuntu wokuqala ukucabanga ngalokhu. Abesifazane abaningi abenza isinqumo sokuhlolwa okunjalo okwesabekayo. Futhi u-Angelina Jolie Pitt wakhanyisa ngokukhanyayo ngendaba emnyama eminyakeni emibili eyedlule lapho ethola ukuthi unoshintsho ekushintsheni kwe-BRCA1 futhi wakhuluma esidlangalaleni ngesinqumo sakhe sokuba ne-mastectomy yokuvimbela ephindwe kabili.

Ingxoxo ithathe kuphela kusukela lapho. Owesifazane ovamile unamaphesenti angu-12 engcupheni yokuba nomdlavuza webele kanye nethuba elingamaphesenti elilodwa kuya kwamabili lokuthola umdlavuza wesibeletho phakathi nokuphila kwakhe. Kepha abesifazane abathwala ukuguquka kohlobo lwe-BRCA1 babheka amathuba angama-81 wamaphesenti okuthi babe nomdlavuza webele esikhathini esithile, kanye namathuba angama-54 amaphesenti okuba nomdlavuza we-ovari.

“Enye yezinto ezishintshe ngempela kule minyaka embalwa edlule ukuthi izindleko zokulandelana kwezakhi zofuzo zehle kakhulu ngempela,” kusho u-Othman Laraki, umsunguli weColor Genomics. Lokho obekuvivinya igazi elibizayo manje sekungukuhluzwa okusheshayo kwamathe cishe okweshumi kwezindleko. "Esikhundleni sezindleko zelebhu ezibizayo, isici esiyinhloko sokuvimbela sibe yikhono lokuqonda nokucubungula ulwazi," usho kanje.

Leyo yinto Umbala oyenza kahle kakhulu-sikhuluma ngokunemba kokuhlola okungamaphesenti angama-99 kanye nemiphumela okulula ukuyiqonda. Ngohlu lonjiniyela abavela ezinkampanini zobuchwepheshe eziphezulu (ezifana ne-Google ne-Twitter), inkampani yenza ukuqonda imiphumela yakho kungesabi futhi kufane noku-oda isidlo sasemini ku-Seamless.

Ngemuva kokucela ikhithi yamathe online ($ 249; getcolor.com), Umbala uletha konke okudingayo ukuthumela kusampula (ngokuyisisekelo, ithubhu yokuhlola okhafulele kuyo). Yonke le nqubo ithatha cishe imizuzu emihlanu futhi ikhithi iza nebhokisi elikhokhelwe kusengaphambili ukuthumela isampula lakho ngqo ebhodini. Ngenkathi i-DNA yakho idlulela ezikhungweni zabo zokuhlola, uMbala ukucela ukuthi uphendule imibuzo embalwa ngomlando womndeni wakho online, okusiza ososayensi baqonde kangcono ukuthi ifa lidlala kanjani engozini yakho yofuzo. Amaphesenti ayishumi kuya kwangu-15 omdlavuza anezakhi zofuzo, okusho ukuthi ubungozi bakho buxhunyaniswe nokuguqulwa okuthile kohlobo lomndeni wakho. Ezakhini zofuzo ezingu-19 ezivezwa ngombala, umuntu oyedwa kuya kwababili kwabayi-100 uhlolwa ukuthi unezakhi zofuzo eyodwa noma ngaphezulu, ngokusho kukaLaraki. (Thola ukuthi kungani umdlavuza webele usukhuphuka.)

Sonke sithwala izinguquko zofuzo-yizo ezisenza abantu ngabanye. Kepha okunye ukuguqulwa kusho ubungozi bezempilo obuyingozi obufuna ukwazi ukuthi-empeleni, zonke izinhlobo zofuzo ezingama-19 ezihlotshaniswa nobungozi bomdlavuza webele nowama-ovari, kanye nezinye izinhlobo zomdlavuza nezifo ezisongela impilo).

Ngokusho kukaLaraki, kumayelana nokuzivikela ngolwazi. Uma uphethe ushintsho oluyingozi, ukubamba umdlavuza webele kusenesikhathi uma kuqhathaniswa nesikhathi sekwephuzile kunomthelela omkhulu emazingeni okusinda. Ngokusho kwe-American Cancer Society, sikhuluma ngamaphesenti angu-100 uma uyibambe esiteji I ngokumelene namaphesenti angu-22 kuphela uma ungayibambi kuze kufike esigabeni IV. Lokho kuyinzuzo enkulu yokwazi izingozi zakho ngaphambi kwesikhathi.

Ngemva kwamaviki ambalwa elebhu, Umbala uthumela imiphumela yakho nge-imeyili efana nale engiyitholile. Ngokusebenzisa i-portal yabo esebenziseka kalula, ungabona ukuthi iziphi izakhi zofuzo, uma zikhona, ezinokuguquka nokuthi lokho kuguquka kungasho ukuthini empilweni yakho. Ukuhlolwa ngakunye kufaka ukubonisana nomeluleki wezofuzo, ozokuhambisa emiphumeleni yakho bese ephendula noma imiphi imibuzo. Uma ubuza, uColour uzothumela imiphumela yakho kudokotela wakho ukuze ukwazi ukusebenza naye ukwenza uhlelo.

Kepha mina? Lapho ekugcineni ngichofoza leyo nkinobho esabekayo "yokubuka imiphumela", ngacishe ngamangala ukuthola ukuthi angiphathi noma yiziphi izinguquko zofuzo eziyingozi kuzakhi zofuzo ze-BRCA noma ngenye indlela. Thola ukukhululeka okukhulu kokukhululeka. Uma ngibheka umlando wami womndeni, ngangikulungele okuphambene (kangangoba angitshelanga abangani noma umndeni ukuthi ngangihlolwa kuze kube yilapho sengithole imiphumela yami). Ukube bebenethemba, bengifuna isikhathi sokuthola ulwazi olwengeziwe nokukhuluma nodokotela wami ngendlela engcono kakhulu yokuhlela ngaphambi kokuxoxa ngesinqumo.

Ingabe lokhu kusho ukuthi angisoze ngakhathazeka ngomdlavuza webele? Vele akunjalo. Njengabesifazane abaningi, ngisenayo ingozi engamaphesenti angu-12 yokuba nalesi sifo ngesikhathi esithile. Ngabe lokhu kusho ukuthi ngingaphumula kancane lula? Nakanjani. Ekugcineni, noma ngabe ubungozi bami bukhulu kangakanani, ngifuna ukulungela ukwenza izinqumo zezempilo ezihlakaniphile, futhi ngemuva kokuhlolwa, ngizizwa ngihlonyiselwe ukwenza lokho. (Qiniseka ukuthi uyazi mayelana ne-American Cancer Society's Update to Guides Cancer Screening Guidelines.)

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