Okwenza Abanye Abesifazane Bangathinteka Kakhulu Kwezinto Zengqondo Ekucindezelekeni Kwangemva Kokubeletha

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Lapho uChrissy Teigen embulele Ubuhle ukuthi wahlushwa ukucindezeleka kwangemva kokubeletha (PPD) ngemuva kokubeletha indodakazi uLuna, waphinde waletha enye inkinga ebalulekile yezempilo yabesifazane phambili naphakathi nendawo. (Sesivele * siyayithanda i-supermodel yokuyitshela njengoba injalo uma kukhulunywa ngezihloko ezinjengokuqiniseka komzimba, inqubo ye-IVF, nokudla kwayo.) Futhi kuvela ukuthi iPPD yinhle kakhulu-ithinta umuntu oyedwa kwabangu-9 abesifazane base-US, ngokusho kweCenters for Disease Control and Prevention (CDC). Futhi abacwaningi balinganisela ukuthi amaphesenti angu-15 kuphela abesifazane abathintekile abathola ukwelashwa. Ngakho thina kufanele khuluma ngakho.

Kungakho simisiwe ukubona ucwaningo lwakamuva luvela eJohns Hopkins University. Kukhombisa ukuthi ukuba nezinga eliphezulu le-hormone elwa nokukhathazeka phakathi nokukhulelwa-ikakhulukazi i-trimester yesibili-kungavikela omama abasheshe babe yi-PPD. Okungcono, nokho, ukuthi lokhu okutholakele okusha ngolunye usuku kungaholela ekuhlolweni nasekwelashweni okusiza ukuvimbela lesi simo. (Inothi eliseceleni: Ubuwazi ukuthi i-epidural inganciphisa ingozi ye-PPD?)

Ocwaningweni, olushicilelwe ku I-Psychoneuroendocrinology, Abaphenyi balinganisa amazinga e-allopregnanolone, okuwumkhiqizo we-progesterone yokuzala ye-hormone eyaziwa ngokuthula kwayo, nomphumela wokulwa nokukhathazeka. Babheka omama abangu-60 ababezokuba ngumama bonke ababeke batholakala benenkinga yemizwa (cabanga: ukucindezeleka okukhulu noma i-bipolar disorder), futhi bahlola amazinga abesifazane ku-trimester yabo yesibili neyesithathu. Ngemuva kokubeletha kwabesifazane, abacwaningi bathola ukuthi labo ababenamazinga aphansi e-allopregnanolone phakathi ne-trimester yesibili babesengozini yokutholakala bene-PPD kunabesifazane abanamazinga aphezulu we-hormone ngaleso sikhathi esifanayo.

"I-Allopregnanolone ilinganiswa nge-nanogram nge-milliliter (ng / mL), futhi kuyo yonke i-ng / mL eyengeziwe, owesifazane wehliswe ngamaphesenti angama-63 engcupheni yakhe ye-PPD," kusho umlobi ocwaningayo uLauren M. Osborne, MD, umsizi womqondisi Isikhungo Sokuphazamiseka Kwemizwelo Yabesifazane eJohns Hopkins University School of Medicine.

Ngesikhathi sokukhulelwa, kokubili i-progesterone ne-allopregnanolone ngokwemvelo ikhuphuka kancane bese iphahlazeka ngesikhathi sokubeletha, kuchaza u-Osborne. Phakathi naleso sikhathi, obunye ubufakazi bubonisa ukuthi inani le-progesterone elidilizwa libe yi-allopregnanolone lingase lehle ngasekupheleni kokukhulelwa. Ngakho-ke kungaba nengqondo ukuthi uma unamazinga aphansi e-allopregnanolone entanta ohlelweni lwakho ngaphambi nje kokuzalwa-bese uzwa ukumiswa kwamahomoni ngesikhathi sokubeletha-ukuthi amazinga akho okukhathazeka angakhuphuka futhi akwenze ube sengozini ye-PPD, yikuphi ukukhathazeka uphawu oluvamile. (Futhi, amaqiniso amaningi okudingeka azi nge-PPD.)

U-Osborne uthi ucwaningo aluwuphenduli ngokugcwele umbuzo wokuthi kungani i-allopregnanolone ikwazi ukuvikela kwi-PPD, "kepha singacabanga ukuthi mhlawumbe amazinga aphansi ku-trimester yesibili ayabandakanyeka ochungechungeni lwemicimbi eholela ku-PPD-noma ama-receptors obuchopho, noma amasosha omzimba, noma olunye uhlelo esingazange sicabange ngalo."

Uphinde aphawule ukuthi abanye besifazane bangase batholakale kalula ku-PPD ngenxa yamazinga aphansi kakade e-allopregnanolone ngaphandle kokukhulelwa, njengoba ubufakazi bubonisa ukuxhumana phakathi kwamazinga aphansi ehomoni nokucindezeleka. (Okuhlobene: Nazi izivivinyo ezinhlanu ezingakusiza ukukulungiselela ukubeletha.)

Lokho kusho ukuthi, akekho ophakamisa ukuthi uphumelele ukuhlolwa kwe-allopregnanolone uma unengane endleleni (noma kunjalo, i-FWIW, kunokuhlolwa kwegazi kwayo). Ngemuva kwakho konke, u-Osborne uyavuma ukuthi lesi yisifundo esincane esinemiphumela yokuqala, ngakho-ke kudingeka kwenziwe olunye ucwaningo oluningi. Plus, yini has okwenziwe kuza nemigede. Okokuqala nokubaluleke kakhulu: Lolu cwaningo lwenziwa neqembu labesifazane abasengozini enkulu, kunalabo ababengatholakali ngaphambi kwesikhathi ngesifo semizwa. Okusho ukuthi abazi okwamanje ukuthi imiphumela efanayo izotholakala lapho kuhlaziywa inani labantu abaningi.

Noma kunjalo, kunikeza ithemba ngalokho okuzayo ngempilo nokwelashwa kwabesifazane. U-Osborne uthi ufisa ukutadisha ukuthi ngabe i-allopregnanolone ingasetshenziswa yini ukuvimbela i-PPD kwabesifazane abasengozini, kanti uJohn Hopkins ungesinye sezikhungo ezimbalwa ezibheka i-allopregnanolone njengokwelashwa kwe-PPD.

Ngakho-ke ngenkathi ososayensi bethambekele kulokho, ukubheja kwakho okuhle ukubeka iso kumizwa yakho. "Cishe bonke abesifazane, cishe amaphesenti angama-80 kuya kwangama-90 - bazoba 'ne-baby blues' [futhi babone ukungazinzi kwemizwa nokukhala ezinsukwini ezimbalwa zokuqala ngemuva kokuzalwa," kusho u-Osborne. "Kodwa izimpawu ezihlala amasonto amabili noma ngaphezulu, noma ezinzima kakhulu, zingase [zibonise] ukucindezeleka kwangemva kokubeletha."

Unenkinga yokulala; ukuzwa ukukhathala; ukukhathazeka ngokweqile (ngengane noma ezinye izinto); ukungabi nemizwa ngengane; izinguquko zokudla; ubuhlungu nezinhlungu; ukuzizwa unecala, ungelutho, noma ungenathemba; ukucasuka; ukuthola ubunzima bokugxila; noma ukucabanga ngokuzilimaza noma ingane konke kuyizimpawu ze-PPD, kusho u-Osborne. (Futhi, ungaphuthelwa yilezi zimpawu eziyisithupha ezicashile zalesi simo.) Uma uhlangabezana nanoma iyiphi yalezi, thinta isisekelo nodokotela wakho ngokushesha okukhulu ngoba ulwelwesi lwesiliva! -Osborne uthi i-PPD iphendula kahle ekwelashweni. Kukhona futhi nePostpartum Support International Branch kuwo wonke amazwe kulabo abafuna izinketho ezingeziwe.

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