I-hyperaldosteronism eyinhloko neyesibili

I-Hyperaldosteronism yisifo lapho i-adrenal gland ikhipha i-hormone aldosterone eningi kakhulu egazini.

I-Hyperaldosteronism ingaba eyinhloko noma yesibili.

I-hyperaldosteronism eyinhloko ingenxa yenkinga yezindlala ze-adrenal uqobo, ezibangela ukuthi zikhulule i-aldosterone eningi kakhulu.

Ngokuphambene nalokho, nge-hyperaldosteronism yesibili, inkinga kwenye indawo emzimbeni ibangela ukuthi izindlala ze-adrenal zikhulule i-aldosterone eningi kakhulu. Lezi zinkinga zingaba ngezakhi zofuzo, ukudla, noma ukugula okwenhliziyo, isibindi, izinso, noma umfutho wegazi ophakeme.

Izimo eziningi ze-hyperaldosteronism eyinhloko zibangelwa isimila esingenasifo (esibi) se-adrenal gland. Lesi simo sithinta kakhulu abantu abaneminyaka engama-30 kuya kwengama-50 ubudala futhi siyimbangela ejwayelekile yomfutho wegazi ophezulu eminyakeni yobudala obuphakathi.

I-hyperaldosteronism eyinhloko neyesibili inezimpawu ezivamile, kufaka phakathi:

• Umfutho wegazi ophezulu
• Izinga eliphansi le-potassium egazini
• Ukuzizwa ngikhathele ngaso sonke isikhathi
• Ubuhlungu bekhanda
• Ubuthakathaka bemisipha
• Ubudikadika

Umhlinzeki wezokunakekelwa kwempilo uzokwenza ukuhlolwa komzimba abuze ngezimpawu zakho.

Ukuhlolwa okungahle kuhlolwe ukuthi kuhlolwe i-hyperaldosteronism kufaka:

• Iskena se-CT esiswini
• ECG
• Izinga le-aldosterone yegazi
• Umsebenzi we-renin wegazi
• Izinga le-potassium yegazi
• I-aldosterone e-Urinary
• Izinso ultrasound

Inqubo yokufaka i-catheter emithanjeni yezindlala ze-adrenal ingadinga ukwenziwa. Lokhu kusiza ukubheka ukuthi yiziphi izindlala ezimbili ze-adrenal ezenza i-aldosterone eningi kakhulu. Lokhu kuhlolwa kubalulekile ngoba abantu abaningi banezicubu ezincane ezinobungozi kuzindlala ze-adrenal ezingakhiphi noma yimaphi ama-hormone. Ukuthembela kuphela ku-CT scan kungaholela ekususweni kwendlala engafanele ye-adrenal.

I-hyperaldosteronism eyinhloko ebangelwa i-adrenal gland tumor ivame ukwelashwa ngokuhlinzwa. Ngezinye izikhathi kungelashwa ngemithi. Ukususa isimila se-adrenal kungalawula izimpawu. Ngisho nangemva kokuhlinzwa, abanye abantu basenomfutho wegazi ophezulu futhi badinga ukuthatha imithi. Kepha imvamisa, inani lemithi noma imithamo lingehliswa.

Ukunciphisa ukusetshenziswa kasawoti nokuphuza umuthi kungalawula izimpawu ngaphandle kokuhlinzwa. Imithi yokwelapha i-hyperaldosteronism ifaka:

• Izidakamizwa ezivimba isenzo se-aldosterone
• Ama-diuretics (amaphilisi amanzi), asiza ukuphatha ukwanda ketshezi emzimbeni

I-hyperaldosteronism yesibili iphathwa ngemithi (njengoba kuchaziwe ngenhla) futhi inciphisa nokudla kukasawoti. Ukuhlinzwa akuvamisile ukusetshenziswa.

Umbono we-hyperaldosteronism eyinhloko muhle ngokuxilongwa nokwelashwa kwasekuqaleni.

Umbono we-hyperaldosteronism yesibili uncike embangela yalesi simo.

I-hyperaldosteronism eyinhloko ingadala umfutho wegazi ophakeme kakhulu, ongalimaza izitho eziningi, kufaka phakathi amehlo, izinso, inhliziyo nobuchopho.

Izinkinga zokwakhiwa kanye ne-gynecomastia (amabele akhulisiwe emadodeni) angenzeka ngokusetshenziswa kwemithi isikhathi eside ukuvimba umphumela we-hyperaldosteronism.

Shayela i-aphoyintimenti nomhlinzeki wakho uma uba nezimpawu ze-hyperaldosteronism.

Isifo se-Conn; I-Mineralocorticoid ngokweqile

• Izindlala ze-Endocrine
• Uketshezi lwe-adrenal gland secretion

UCarey RM, uPadia SH. Ukuphazamiseka ngokweqile kwe-mineralocorticoid kanye nomfutho wegazi ophezulu. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 108.

UNieman LK. I-adrenal cortex. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 214.