I-amyloidosis eyifa

I-hereditary amyloidosis yisimo lapho kufakwa khona amaprotheni angavamile (abizwa ngama-amyloid) cishe kuzo zonke izicubu zomzimba. Idiphozi enobungozi ivame ukwakheka enhliziyweni, ezinso, nasezinhlelweni zezinzwa. Lawa maprotheni abeka imali kulimaza izicubu futhi aphazamise nokuthi izitho zisebenza kanjani.

I-hereditary amyloidosis idluliselwa kusuka kubazali iye ezinganeni zabo (ezuzwe njengefa). Izakhi zofuzo nazo zingadlala indima ku-amyloidosis eyinhloko.

Ezinye izinhlobo ze-amyloidosis azizuzwa njengefa. Kubandakanya:

• Uhlelo lweSenile: lubonwa kubantu abadala kunama-70
• Okuzenzakalelayo: kwenzeka ngaphandle kwesizathu esaziwayo
• Okwesibili: imiphumela yezifo ezinjengomdlavuza wamaseli egazi (myeloma)

Izimo ezithile zifaka:

• I-amyloidosis yenhliziyo
• I-cerebral amyloidosis
• I-amyloidosis yesibili yesistimu

Ukwelashwa kokuthuthukisa ukusebenza kwezitho ezilimele kuzosiza ukukhulula ezinye izimpawu ze-amyloidosis yefa. Ukufakelwa kwesibindi kungasiza ukunciphisa ukwakhiwa kwamaprotheni ayingozi e-amyloid. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nokwelashwa.

I-Amyloidosis - ifa; I-amyloidosis ejwayelekile

• I-Amyloidosis yeminwe

UBudd RC, uSeldin DC. I-Amyloidosis. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, abahleli. Incwadi kaKelley noFirestein yeRheumatology. Umhlaka 10. IPhiladelphia, PA: Elsevier; I-2017: isahluko 116.

UGertz MA. I-Amyloidosis. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 179.

I-Hawkins PN. I-Amyloidosis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, abahleli. I-Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2019: isahluko 177.