I-Proton pump inhibitors

Ama-Proton pump inhibitors (ama-PPIs) yimithi esebenza ngokunciphisa inani le-asidi esiswini elenziwa yizindlala kulwelwesi lwesisu sakho.

I-Proton pump inhibitors isetshenziselwa:

• Yehlisa izimpawu ze-acid reflux, noma isifo se-reflux se-gastroesophageal (GERD). Lesi yisimo lapho ukudla noma uketshezi kukhuphuka kusuka esiswini kuya emungeni (ithubhu lisuka emlonyeni liye esiswini).
• Phatha isilonda esiswini noma esiswini (esiswini).
• Phatha ukulimala komphimbo ongezansi obangelwa yi-acid reflux.

Kunamagama amaningi nemikhiqizo yama-PPIs. Iningi lisebenza ngokulinganayo. Imiphumela emibi ingahluka kuye ngezidakamizwa.

• I-Omeprazole (Prilosec), nayo iyatholakala ngaphezulu kwe-the-counter (ngaphandle kwemithi kadokotela)
• I-Esomeprazole (Nexium), nayo iyatholakala ngaphezulu kwe-the-counter (ngaphandle kwemithi kadokotela)
• I-Lansoprazole (Prevacid), nayo iyatholakala ngaphezulu kwe-counter (ngaphandle kwemithi kadokotela)
• I-Rabeprazole (AcipHex)
• I-Pantoprazole (Protonix)
• I-Dexlansoprazole (Dexilant)
• I-Zegerid (i-omeprazole ene-sodium bicarbonate), nayo iyatholakala ngaphezulu kwe-counter (ngaphandle kwencwadi kadokotela)

Ama-PPI athathwa ngomlomo. Atholakala njengamaphilisi noma amaphilisi. Imvamisa, le mithi ithathwa imizuzu engama-30 ngaphambi kokudla kokuqala kosuku.

Ungathenga amanye ama-PPIs esitolo ngaphandle kwencwadi kadokotela. Khuluma nomhlinzeki wakho wezempilo uma uthola ukuthi kufanele uphuze le mithi ezinsukwini eziningi. Abanye abantu abane-acid reflux bangadinga ukuthatha ama-PPIs nsuku zonke. Abanye bangalawula izimpawu nge-PPI nsuku zonke.

Uma une-ulcer peptic, udokotela wakho angakunikeza ama-PPIs kanye neminye imithi emi-2 noma emi-3 kuze kube amasonto amabili. Noma umhlinzeki wakho angakucela ukuthi uthathe le mithi amasonto ayi-8.

Uma umhlinzeki wakho ekuchazela le mithi:

• Thatha yonke imithi yakho njengoba utshelwe.
• Zama ukuwathatha ngasikhathi sinye usuku ngalunye.
• UNGAYEKISI ukuthatha imishanguzo yakho ngaphandle kokukhuluma nomhlinzeki wakho kuqala. Landela umhlinzeki wakho njalo.
• Hlela kusengaphambili ukuze ungaphelelwa yimithi. Qiniseka ukuthi unokwanele nawe lapho usohambweni.

Imiphumela emibi evela kuma-PPIs ayivamile. Ungahle uphathwe yikhanda, uhudo, ukuqunjelwa, isicanucanu, noma ukulunywa. Buza umhlinzeki wakho mayelana nokukhathazeka okungenzeka kusetshenziswe isikhathi eside, njengokungenwa yizifo kanye nokuphuka kwethambo.

Uma uncelisa noma ukhulelwe, khuluma nomhlinzeki wakho wezempilo ngaphambi kokuthatha le mithi.

Tshela udokotela wakho uma usebenzisa neminye imithi. Ama-PPI angashintsha indlela izidakamizwa ezithile ezisebenza ngayo, kufaka phakathi eminye imithi elwa nokuquleka kanye nezinciphisi zegazi ezifana ne-warfarin noma i-clopidogrel (i-Plavix).

Shayela umhlinzeki wakho uma:

• Unemiphumela engemihle evela kule mithi
• Unezinye izimpawu ezingavamile
• Izimpawu zakho azithuthuki

Ama-PPI

U-Aronson JK. I-Proton pump inhibitors. Ku: Aronson JK, ed. Imiphumela emibi kaMeyler yezidakamizwa. Umhla ka-16. UWalthman, MA: Elsevier; 2016: 1040-1045.

Katz PO, Gerson LB, Vela MF. Imihlahlandlela yokuxilongwa nokuphathwa kwesifo se-reflux se-gastroesophageal. NginguJ Gastroenterol. 2013; 108 (3): 308-328. I-PMID: 23419381 www.ncbi.nlm.nih.gov/pubmed/23419381.

IKuipers EJ, uBlaser MJ. Isifo se-acid peptic. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 139.

URichter JE, uFriedenberg FK. Isifo se-reflux se-gastroesophageal. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 44.