Ukuhlolwa kwegazi kwe-hormone ye-Antidiuretic

Ukuhlolwa kwegazi kwe-Antidiuretic kukala izinga le-hormone elwa namagciwane (ADH) egazini.

Kudingeka isampula yegazi.

Khuluma nomhlinzeki wakho wezokunakekelwa kwezempilo ngemithi yakho ngaphambi kokuhlolwa. Izidakamizwa eziningi zingathinta izinga le-ADH, kufaka phakathi:

• Utshwala
• I-diuretics (amaphilisi wamanzi)
• Imithi yengcindezi yegazi
• I-insulini
• Imithi yokuphazamiseka kwengqondo
• I-Nicotine
• Ukuphuza ama-steroid

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

I-ADH yihomoni ekhiqizwa engxenyeni yobuchopho ebizwa nge-hypothalamus. Ibe seyigcinwa bese idedelwa kwi-pituitary, indlala encane engaphansi kobuchopho. I-ADH isebenza ezinso ukulawula inani lamanzi akhishwe emchameni.

Ukuhlolwa kwegazi kwe-ADH kuyalwa lapho umhlinzeki wakho esola ukuthi unenkinga ethinta izinga lakho le-ADH njenge:

• Ukwanda ketshezi emzimbeni wakho okubangela ukuvuvukala noma ukukhukhumala (i-edema)
• Umchamo owedlulele
• Izinga eliphansi le-sodium (usawoti) egazini lakho
• Ukoma okunamandla noma okungalawuleki

Izifo ezithile zithinta ukukhishwa okujwayelekile kwe-ADH. Izinga legazi le-ADH kumele lihlolwe ukuthola imbangela yalesi sifo. I-ADH ingalinganiswa njengengxenye yokuhlolwa kokuvinjelwa kwamanzi ukuthola imbangela yesifo.

Amanani ajwayelekile we-ADH angaba kusuka ku-1 kuye ku-5 pg / mL (0.9 kuye ku-4.6 pmol / L).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene.Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga eliphakeme kunokujwayelekile lingavela lapho kukhishwa i-ADH eningi kakhulu, kungaba ebuchosheni lapho yenziwa khona, noma kwenye indawo emzimbeni. Lokhu kubizwa nge-syndrome ye-ADH engafanele (SIADH).

Izimbangela ze-SIADH zifaka:

• Ukulimala kobuchopho noma ukuhlukumezeka
• Izicubu zobuchopho
• Ukungalingani kwamanzi ngemuva kokuhlinzwa
• Ukutheleleka ebuchosheni noma esikhunjeni esizungeze ubuchopho
• Ukutheleleka emaphashini
• Imithi ethile, njengezinye izidakamizwa zokubamba, imithi yezinhlungu, kanye ne-anti-depressants
• Umdlavuza omncane wamaphaphu we-carcinoma
• Unhlangothi

Izinga eliphakeme kunokujwayelekile le-ADH lingatholakala kubantu abanesifo senhliziyo, ukwehluleka kwesibindi, noma ezinye izinhlobo zezifo zezinso.

Izinga eliphansi kunokujwayelekile lingaveza:

• Ukulimala kwe-hypothalamus noma i-pituitary gland
• I-Central diabetes insipidus (isimo lapho izinso zingakwazi ukonga amanzi)
• Ukoma ngokweqile (polydipsia)
• Uketshezi oluningi kakhulu emithanjeni yegazi (ivolumu ngokweqile)

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-arginine vasopressin; I-hormone ye-Antidiuretic; I-AVP; IVasopressin

IChernecky CC, iBerger BJ. I-hormone Antidiuretic (ADH) - serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 146.

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

I-Oh MS, i-Briefel G. Ukuhlolwa kokusebenza kwezinso, amanzi, ama-electrolyte, ne-acid-base balance. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 14.