IHodgkin lymphoma

I-Hodgkin lymphoma ingumdlavuza wezicubu ze-lymph. Izicubu zomzimba zitholakala kuma-lymph node, ubende, isibindi, umnkantsha namanye amasayithi.

Isizathu seHodgkin lymphoma asaziwa. I-Hodgkin lymphoma ivame kakhulu kubantu abaneminyaka engu-15 kuya kwengama-35 ubudala kanye neminyaka engama-50 kuya kwengu-70 ubudala. Ukutheleleka kwangaphambilini ngegciwane le-Epstein-Barr (EBV) kucatshangwa ukuthi kunomthelela kwezinye izimo. Abantu abanegciwane lesandulela ngculaza basengozini enkulu uma kuqhathaniswa nabantu abaningi.

Isibonakaliso sokuqala seHodgkin lymphoma imvamisa i-lymph node evuvukile evela ngaphandle kwesizathu esaziwayo. Lesi sifo singasakazeka kuma-lymph node aseduze. Kamuva ingase isabalale iphele, isibindi, umnkantsha, noma ezinye izitho.

Izimpawu zingafaka noma yikuphi okulandelayo:

• Ukuzizwa ngikhathele kakhulu ngaso sonke isikhathi
• Imfiva nokugodola okufika kudlule
• Ukulunywa umzimba wonke okungachazeki
• Ukuphelelwa isifiso sokudla
• Kumanzisa ukujuluka ebusuku
• Ukuvuvukala okungenasici kwama-lymph node entanyeni, emakhwapheni, noma emgodini (izindlala ezivuvukele)
• Ukwehla kwesisindo okungachazeki

Ezinye izimpawu ezingase zivele ngalesi sifo:

• Ukukhwehlela, izinhlungu zesifuba, noma izinkinga zokuphefumula uma kukhona ama-lymph node avuvukile esifubeni
• Ukujuluka okweqile
• Ubuhlungu noma umuzwa wokugcwala ngaphansi kwezimbambo ngenxa yokuvuvukala ubende noma isibindi
• Ubuhlungu kuma-lymph node ngemuva kokuphuza utshwala
• Ukuqhakaza isikhumba noma ukuqhuma

Izimpawu ezibangelwa yiHodgkin lymphoma zingenzeka nezinye izimo. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yezimpawu zakho ezithile.

Umhlinzeki uzokwenza ukuhlolwa ngokomzimba futhi ahlole izindawo zomzimba ezinama-lymph node ukuzwa ukuthi zivuvukile yini.

Lesi sifo sivame ukutholakala ngemuva kwe-biopsy yezicubu ezisolwayo, imvamisa i-lymph node.

Izinqubo ezilandelayo zivame ukwenziwa:

• Ukuhlolwa kwamakhemikhali egazi kufaka phakathi amazinga wamaprotheni, ukuhlolwa kokusebenza kwesibindi, ukuhlolwa kokusebenza kwezinso, kanye nezinga le-uric acid
• I-bone marrow biopsy
• Ukuskena kwe-CT kwesifuba, kwesisu, nesinqe
• Qedela ukubalwa kwegazi (CBC) ukuhlola i-anemia nokubala kwegazi elimhlophe
• Ukuskena kwe-PET

Uma izivivinyo zibonisa ukuthi une-Hodgkin lymphoma, kuzokwenziwa izivivinyo eziningi ukubona ukuthi umdlavuza usabalale kangakanani. Lokhu kubizwa ngokuthi isiteji. Isiteji sisiza ukuqondisa ukwelashwa nokulandelela.

Ukwelashwa kuncike kulokhu okulandelayo:

• Uhlobo lweHodgkin lymphoma (kunezinhlobo ezahlukahlukene zeHodgkin lymphoma)
• Isiteji (lapho isifo sesisabalale khona)
• Iminyaka yakho nezinye izindaba zezokwelapha
• Ezinye izinto, kufaka phakathi ukwehla kwesisindo, ukujuluka ebusuku, nomkhuhlane

Ungathola i-chemotherapy, i-radiation therapy, noma kokubili. Umhlinzeki wakho angakutshela kabanzi mayelana nokwelashwa kwakho okuthile.

I-chemotherapy ephezulu kakhulu inganikezwa lapho iHodgkin lymphoma ibuya ngemuva kokwelashwa noma ingaphenduli ekwelashweni kokuqala. Lokhu kulandelwa ukufakelwa kwe-stem cell esebenzisa amaseli akho ama-stem.

Wena nomhlinzeki wakho ningadinga ukuphatha ezinye izinto ezikhathazayo ngesikhathi sokwelashwa, kufaka phakathi:

• Ukuphatha izilwane ezifuywayo ngesikhathi se-chemotherapy
• Izinkinga zokopha
• Umlomo owomile
• Ukudla amakhalori anele

Unganciphisa ukucindezela kokugula ngokujoyina iqembu lokusekela umdlavuza. Ukwabelana nabanye abanokuhlangenwe nakho okuvamile kungakusiza ungazizwa uwedwa.

IHodgkin lymphoma ingenye yomdlavuza owelaphekayo. Ukwelashwa kungenzeka kakhulu uma kutholakala futhi kwelashwa kusenesikhathi. Ngokungafani neminye imidlavuza, iHodgkin lymphoma nayo iyelapheka kakhulu ngezigaba zayo zokugcina.

Uzodinga ukuba nezivivinyo ezijwayelekile iminyaka ngemuva kokwelashwa kwakho. Lokhu kusiza umhlinzeki wakho ahlole izimpawu zokubuya komdlavuza kanye neminye imiphumela yokwelashwa yesikhathi eside.

Ukwelashwa kweHodgkin lymphoma kungaba nezinkinga. Izinkinga zesikhathi eside zokwelashwa ngamakhemikhali noma ukwelashwa ngemisebe zifaka:

• Izifo zomnkantsha we-Bone (njenge-leukemia)
• Isifo senhliziyo
• Ukungakwazi ukuthola izingane (ukungazali)
• Izinkinga zamaphaphu
• Eminye imidlavuza
• Izinkinga ze-thyroid

Qhubeka ulandela umhlinzeki owaziyo ngokuqapha nokuvimbela lezi zinkinga.

Shayela umhlinzeki wakho uma:

• Unezimpawu zeHodgkin lymphoma
• Une-Hodgkin lymphoma futhi unemiphumela emibi evela ekwelashweni

ILymphoma - iHodgkin; Isifo se-Hodgkin; Umdlavuza - Hodgkin lymphoma

• Ukufakelwa komnkantsha wethambo - ukukhipha
• I-Chemotherapy - yini ongayibuza udokotela wakho
• Imisebe yesifuba - ukukhishwa
• Ukudla ama-calories amaningi lapho ugula - abantu abadala
• Imisebe yomlomo nentamo - ukukhipha
• Ukwelashwa ngemisebe - imibuzo ongayibuza udokotela wakho
• Lapho unesicanucanu nokuhlanza

• Uhlelo lweLymphatic
• Isifo sikaHodgkin - ukubandakanyeka kwesibindi
• I-Lymphoma, ebulalayo - i-CT scan
• Izakhiwo zesistimu yomzimba

UBartlett N, uTriska G. Hodgkin lymphoma. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, abahleli. I-Abeloff’s Clinical Oncology. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2020: isahluko 102.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa kwe-Adult Hodgkin lymphoma (PDQ) - inguqulo yezempilo. www.cancer.gov/types/lymphoma/hp/ultult-hodgkin-treatment-pdq. Kubuyekezwe uJanuwari 22, 2020. Kufinyelelwe ngoFebhuwari 13, 2020.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa kweHodgkin lymphoma ebuntwaneni (PDQ) - inguqulo yezobuchwepheshe yezempilo. www.cancer.gov/types/lymphoma/hp/child-hodgkin- ukwelashwa-pdq. Kubuyekezwe ngoJanuwari 31, 2020. Kufinyelelwe ngoFebhuwari 13, 2020.

Iwebhusayithi ye-National Comprehensive Cancer Network. Imikhombandlela ye-NCCN yokwenza imitholampilo ku-oncology: Hodgkin lymphoma. Inguqulo 1.2020. www.nccn.org/professionals/physician_gls/pdf/hodgkins.pdf. Kubuyekezwe ngoJanuwari 30, 2020. Kufinyelelwe ngoFebhuwari 13, 2020.