Izinhlobo zokwelashwa kwamahomoni

Ukwelashwa kweHormone (HT) kusebenzisa ihomoni eyodwa noma amaningi ukwelapha izimpawu zokunqamuka kokuya esikhathini. I-HT isebenzisa i-estrogen, i-progestin (uhlobo lwe-progesterone), noma kokubili. Kwesinye isikhathi i-testosterone nayo iyangezwa.

Izimpawu zokunqamuka kokuya esikhathini zihlanganisa:

• Ukushisa okushisayo
• Ukujuluka ebusuku
• Izinkinga zokulala
• Ukoma kwesitho sangasese sowesifazane
• Ukukhathazeka
• Ukuzithokozisa
• Intshisekelo encane kwezocansi

Ngemuva kokunqamuka kokuya esikhathini, umzimba wakho uyeka ukwenza i-estrogen ne-progesterone. I-HT ingaphatha izimpawu zokunqamuka kokuya esikhathini ezikukhathazayo.

I-HT inezingozi ezithile. Kungakhuphula ubungozi bakho:

• Amahlule egazi
• Umdlavuza webele
• Isifo senhliziyo
• Unhlangothi
• Amatshe amatshe amade

Ngaphandle kwalokhu kukhathazeka, kwabesifazane abaningi, i-HT yindlela ephephile yokwelapha izimpawu zokunqamuka kokuya esikhathini.

Njengamanje, ochwepheshe akucaci ukuthi kufanele uthathe i-HT isikhathi esingakanani. Amanye amaqembu ochwepheshe asikisela ukuthi ungathatha i-HT yezimpawu zokunqamuka kokuya esikhathini isikhathi eside uma singekho isizathu sezokwelapha sokuyeka umuthi. Kwabesifazane abaningi, amanani aphansi we-HT angenela ukulawula izimpawu eziyinkinga. Ukweqiwa okuphansi kwe-HT kuvame ukuba nemiphumela engemihle embalwa. Lezi yizo zonke izingqinamba okufanele uxoxe ngazo nomhlinzeki wakho wezokunakekelwa kwempilo.

I-HT iza ngezindlela ezahlukahlukene. Ungahle udinge ukuzama izinhlobo ezahlukahlukene ngaphambi kokuthola okukusebenzela kangcono.

I-Estrogen iza:

• Isifutho sekhala
• Amaphilisi noma amaphilisi, athathwe ngomlomo
• Ijeli lesikhumba
• Amachashazi esikhumba, asetshenziswa ethangeni noma esiswini
• Okhilimu besitho sangasese sowesifazane noma amaphilisi esitho sangasese sowesifazane ukusiza ukoma nobuhlungu ngokuya ocansini
• Indandatho yesitho sangasese sowesifazane

Iningi labesifazane abathatha i-estrogen futhi abasenaso isibeletho sabo nabo badinga ukuthatha iprogestin. Ukuthatha womabili ama-hormone ndawonye kwehlisa ingozi yomdlavuza we-endometrial (uterine). Abesifazane abakhishwe isibeletho abakwazi ukuthola umdlavuza we-endometrial. Ngakho-ke, kunconywa i-estrogen kuphela.

Iprogesterone noma i-progestin ingena:

• Amaphilisi
• Izikhumba zezikhumba
• Ukhilimu wesitho sangasese sowesifazane
• Amakhandlela wesitho sangasese sowesifazane
• Idivayisi ye-intrauterine noma uhlelo lwe-intrauterine

Uhlobo lwe-HT oludonswa udokotela wakho lungaxhomeka ekutheni unaziphi izimpawu zokunqamuka kokuya esikhathini. Isibonelo, amaphilisi noma amabala angalapha ukujuluka ebusuku. Amasongo esitho sangasese sowesifazane, okhilimu, noma amaphilisi asiza ukuqeda ukoma kwesitho sangasese sowesifazane.

Xoxa ngezinzuzo nezingozi ze-HT nomhlinzeki wakho.

Lapho uthatha i-estrogen ne-progesterone ndawonye, ​​udokotela wakho angase asikisele elinye lamashejuli alandelayo:

Ukwelashwa kwe-cyclic hormone kuvame ukunconywa lapho uqala ukuya esikhathini.

• Uphuza i-estrogen njengephilisi noma uyisebenzise ngendlela ye-patch izinsuku ezingama-25.
• I-Progestin ingezwa phakathi kwezinsuku eziyi-10 no-14.
• Usebenzisa i-estrogen ne-progestin ndawonye isikhathi esisele sezinsuku ezingama-25.
• Awuthathi noma yimaphi ama-hormone izinsuku ezi-3 kuye kwezi-5.
• Ungahle ube nokopha njalo ngenyanga nge-cyclic therapy.

Ukwelashwa okuhlanganisiwe yilapho uthatha khona i-estrogen ne-progestin ndawonye nsuku zonke.

• Ungahle ube nokopha okungavamile lapho uqala noma ushintshela kule shejuli ye-HT.
• Iningi labesifazane liyeka ukopha kungakapheli unyaka.

Udokotela wakho angakunikeza eminye imithi uma unezimpawu ezinzima noma unengozi enkulu yokwelashwa kwamathambo. Isibonelo, futhi ungathatha i-testosterone, i-hormone yesilisa, ukwenza ngcono idrayivu yakho yezocansi.

I-HT ingaba nemiphumela emibi, kufaka phakathi:

• Ukuqhakaza
• Ubuhlungu besifuba
• Ukuphathwa ikhanda
• Ukushintsha kwemizwelo
• Isicanucanu
• Ukugcinwa kwamanzi
• Ukopha okungafanele

Tshela udokotela wakho uma ubona imiphumela emibi. Ukushintsha umthamo noma uhlobo lwe-HT oluthathayo kungasiza ekunciphiseni le miphumela emibi. Ungashintshi umthamo wakho noma uyeke ukuthatha i-HT ngaphambi kokukhuluma nodokotela wakho.

Uma wopha esithweni sangasese sowesifazane noma ezinye izimpawu ezingavamile ngesikhathi se-HT, shayela udokotela wakho.

Qiniseka ukuthi uqhubeka nokubona udokotela wakho ukuze akuhlole njalo lapho uthatha i-HT.

Izinhlobo ze-HRT; Ukwelashwa kwe-Estrogen esikhundleni - izinhlobo; Izinhlobo ze-ERT zokwelashwa kwamahomoni; Ukwelashwa esikhundleni seHormone - izinhlobo; Ukunqamuka kokuya esikhathini - izinhlobo zokwelashwa kwamahomoni; Izinhlobo ze-HT; Izinhlobo ze-Menopausal hormone

Umbono wekomidi le-ACOG cha. 565: Ukwelashwa kweHormone nesifo senhliziyo. Isikhubekiso seGynecol. 2013; 121 (6): 1407-1410. I-PMID: 23812486 pubmed.ncbi.nlm.nih.gov/23812486/.

UCosman F, de Beur SJ, LeBoff MS, et al. Umhlahlandlela womtholampilo wokuvimbela nokwelashwa kwe-osteoporosis. Osteoporos Int. 2014; 25 (10): 2359-2381. I-PMID: 25182228 pubmed.ncbi.nlm.nih.gov/25182228/.

de Villiers TJ, Hall JE, Pinkerton JV, et al. Isitatimende esibuyekeziwe sokuvumelana komhlaba wonke mayelana nokwelashwa kwe-menopausal hormone. Isimo sezulu. 2016; 19 (4): 313-315. I-PMID: 27322027 pubmed.ncbi.nlm.nih.gov/27322027/.

Lobo RA. Ukunqamuka kokuya esikhathini nokunakekelwa kowesifazane ovuthiwe: i-endocrinology, imiphumela yokushoda kwe-estrogen, imiphumela yokwelashwa kwamahomoni, nezinye izindlela zokwelashwa. Ku: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. I-Gynecology ephelele. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2017: isahluko 14.

IMagowan BA, Owen P, Thomson A. Ukwelashwa kokunqamuka kokuya esikhathini kanye ne-hormone. Ku: Magowan BA, Owen P, Thomson A, eds. I-Clinical Obstetrics ne-Gynecology. Umhla wesi-4. Elsevier; 2019: isahluko 9.

UStuenkel CA, uDavis SR, uGompel A, et al. Ukwelashwa kwezimpawu zokunqamuka kokuya esikhathini: umhlahlandlela wokuziphatha we-Endocrine Society. UJ Clin Endocrinol Metab. 2015; 100 (11): 3975-4011. I-PMID: 26444994 pubmed.ncbi.nlm.nih.gov/26444994/.

• Ukwelashwa Okubuyisela IHormone
• Ukunqamuka kokuya esikhathini