I-Neurosarcoidosis

I-Neurosarcoidosis iyinkinga ye-sarcoidosis, lapho ukuvuvukala kwenzeka khona ebuchosheni, emgogodleni nakwezinye izindawo zesistimu yezinzwa.

I-Sarcoidosis yisifo esingelapheki esithinta izingxenye eziningi zomzimba, ikakhulu amaphaphu. Kubantu abambalwa, lesi sifo sihilela ingxenye ethile yesimiso sezinzwa. Lokhu kubizwa nge-neurosarcoidosis.

I-Neurosarcoidosis ingathinta noma iyiphi ingxenye yesistimu yezinzwa. Ngokuphazima kweso, ubuthakathaka bobuso (ukukhubazeka kobuso noma ukwehla kobuso) uphawu oluvamile lwezinzwa olubandakanya izinzwa zemisipha yobuso. Noma iyiphi enye inzwa esokhakhayini ingathinteka, kufaka phakathi leyo esweni nalabo abalawula ukunambitheka, ukuhogela, noma ukuzwa.

Intambo yomgogodla ingenye ingxenye yohlelo lwezinzwa i-sarcoidosis engayithinta. Abantu bangaba nobuthakathaka ezingalweni nasemilenzeni, nobunzima bokuhamba noma ukulawula umchamo noma amathumbu abo. Kwezinye izimo, umgogodla uthinteka kakhulu kangangokuthi yomibili imilenze ikhubazekile.

Isimo singathinta nezingxenye zobuchopho ezibandakanyekile ekulawuleni imisebenzi eminingi yomzimba, njengokushisa, ukulala nezimpendulo zokuxineka.

Ubuthakathaka bemisipha noma ukulahleka kwezinzwa kungenzeka ngokubandakanyeka kwemizwa yezinzwa. Ezinye izindawo zobuchopho, kufaka phakathi i-pituitary gland esezansi kobuchopho, noma umgogodla nawo ungabandakanyeka.

Ukubandakanywa kwendlala ye-pituitary kungadala:

• Izinguquko ezikhathini zokuya esikhathini
• Ukukhathala ngokweqile noma ukukhathala
• Ukoma ngokweqile
• Ukukhishwa okuphezulu komchamo

Izimpawu ziyahlukahluka. Noma iyiphi ingxenye yesistimu yezinzwa ingathinteka. Ukubandakanywa kobuchopho noma izinzwa ze-cranial kungadala:

• Ukudideka, ukudideka
• Ukwehla kokuzwa
• Ukuwohloka komqondo
• Isiyezi, i-vertigo, noma imizwa engavamile yokuhamba
• Ukubona kabili noma ezinye izinkinga zombono, kufaka phakathi ukungaboni
• Ukukhubazeka ebusweni (ubuthakathaka, ukulenga)
• Ubuhlungu bekhanda
• Ukulahlekelwa iphunga
• Ukulahleka komuzwa wokunambitha, ukunambitheka okungavamile
• Ukuphazamiseka kwengqondo
• Ukuquleka
• Ukukhubazeka kwenkulumo

Ukubandakanyeka kwemisipha eyodwa noma ngaphezulu yomngcele kungaholela ku:

• Imizwa engavamile kunoma iyiphi ingxenye yomzimba
• Ukulahleka kokuhamba kwanoma iyiphi ingxenye yomzimba
• Ukulahlekelwa umuzwa kunoma iyiphi ingxenye yomzimba
• Ubuthakathaka banoma yisiphi isitho somzimba

Ukuhlolwa kungakhombisa izinkinga ngomzwa owodwa noma ngaphezulu.

Umlando we-sarcoidosis olandelwa yizimpawu ezihlobene nemizwa uphakamisa kakhulu i-neurosarcoidosis. Kodwa-ke, izimpawu zalesi simo zingalingisa okunye ukuphazamiseka kwezokwelapha, kufaka phakathi i-insipidus yesifo sikashukela, i-hypopituitarism, i-optic neuritis, i-meningitis, kanye nezicubu ezithile. Kwesinye isikhathi, uhlelo lwezinzwa lungathinteka ngaphambi kokuba umuntu aziwe ukuthi une-sarcoidosis, noma ngaphandle kokuthinta amaphaphu noma ezinye izitho nhlobo.

Ukuhlolwa kwegazi akusizi kakhulu ekutholeni isimo. Ukubhoboza i-lumbar kungakhombisa izimpawu zokuvuvukala. Amazinga akhuphukile we-enzyme eguqula i-angiotensin angatholakala egazini noma ku-cerebrospinal fluid (CSF). Kodwa-ke, lokhu akusikho ukuhlolwa okuthembekile kokuxilonga.

I-MRI yobuchopho ingasiza. I-x-ray yesifuba ivame ukuveza izimpawu ze-sarcoidosis yamaphaphu. I-biopsy yemithambo yezicubu zemizwa ethintekile iqinisekisa lesi sifo.

Alikho ikhambi elaziwayo le-sarcoidosis. Ukwelashwa kunikezwa uma izimpawu zinzima noma ziba zimbi kakhulu. Inhloso yokwelashwa ukunciphisa izimpawu.

Ama-Corticosteroids anjenge-prednisone anqunyelwe ukunciphisa ukuvuvukala. Zivame ukunikezwa kuze kube yilapho izimpawu ziba ngcono noma zihamba. Ungahle udinge ukuthatha imithi izinyanga, noma ngisho neminyaka.

Eminye imishanguzo ingafaka ukufaka esikhundleni se-hormone nemithi ecindezela amasosha omzimba.

Uma unenkinga yokuba ndikindiki, ubuthakathaka, ukubona noma ukuzwa, noma ezinye izinkinga ngenxa yokulimala kwemizwa ekhanda, ungadinga ukwelashwa ngokomzimba, izinsimbi, udondolo, isihambahamba noma isihlalo esinamasondo.

Ukuphazamiseka kwengqondo noma ukuwohloka komqondo kungadinga imishanguzo yokudangala, ukungenelela kwezokuphepha, kanye nosizo ngokunakekelwa.

Amanye amacala ahamba ngokwawo ezinyangeni ezine kuya kweziyisithupha. Abanye bayaqhubeka nokuqhubeka impilo yomuntu wonke. I-Neurosarcoidosis ingadala ukukhubazeka unomphela futhi, kwezinye izimo, nokufa.

Izinkinga ziyahlukahluka kuye ngokuthi iyiphi ingxenye yesistimu yezinzwa ebandakanyekayo nokuthi uphendula kanjani ekwelashweni. Kancane kancane ukwanda noma ukulahlekelwa unomphela komsebenzi wezinzwa kungenzeka. Ezimweni ezingavamile, i-brainstem ingabandakanyeka. Lokhu kusongela impilo.

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma une-sarcoidosis futhi noma yiziphi izimpawu zemizwa zenzeka.

Iya egumbini labezimo eziphuthumayo noma ushayele inombolo ephuthumayo yendawo (enjenge-911) uma ulahlekelwe ngokungazelelwe ukuzwa, ukunyakaza, noma ukusebenza komzimba.

Ukwelashwa okunamandla kwe-sarcoidosis kuvala impendulo engafanele yomzimba womzimba ngaphambi kokuba izinzwa zakho zonakaliswe. Lokhu kunganciphisa ithuba lokuthi kwenzeke izimpawu zezinzwa.

I-Sarcoidosis - uhlelo lwezinzwa

• I-Sarcoid, isigaba I - i-x-ray yesifuba
• I-Sarcoid, isigaba II - i-x-ray yesifuba
• I-Sarcoid, isigaba IV - i-x-ray yesifuba

Iannuzzi MC. I-Sarcoidosis. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 95.

Ibitoye RT, Wilkins A, Ukuthethisa NJ. I-Neurosarcoidosis: indlela yokwelashwa yokuxilonga nokuphatha. UJ Neurol. 2017; 264 (5): 1023-1028. I-PMID: 27878437 www.ncbi.nlm.nih.gov/pubmed/27878437.

UJosephson SA, u-Aminoff MJ. Izinkinga ze-neurological zesifo se-systemic: abantu abadala. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 58.

UKrumholz A, uStern BJ. I-Sarcoidosis yesistimu yezinzwa. Ku: Aminoff MJ, Josephson SW, ama-eds. I-Neurology ne-General Medicine ka-Aminoff. Umhlaka 5. I-Waltham, MA: I-Elsevier Academic Press; 2014: isahluko 49.

UTavee JO, uStern BJ. I-Neurosarcoidosis. Umtholampilo Chest Med. 2015; 36 (4): 643-656. I-PMID: 26593139 www.ncbi.nlm.nih.gov/pubmed/26593139.