Ukukhubazeka okuqhubekayo kwe-supranuclear
I-Progressive supranuclear palsy (PSP) ukuphazamiseka kokuhamba okwenzeka kusukela ekulimaleni kwamanye amangqamuzana emizwa ebuchosheni.
I-PSP yisimo esidala izimpawu ezifana nalezo zesifo i-Parkinson.
Kubandakanya ukonakala kumaseli amaningi obuchopho. Izindawo eziningi zithintekile, kufaka phakathi ingxenye yobuchopho lapho amaseli alawula ukunyakaza kwamehlo atholakala khona. Indawo yobuchopho elawula ukuqina lapho uhamba nayo iyathinteka. Ama-lobes angaphambili obuchopho nawo ayathinteka, okuholela ekuguqulweni kobuntu.
Ayaziwa imbangela yokulimala kwamangqamuzana obuchopho. I-PSP iba yimbi ngokuhamba kwesikhathi.
Abantu abane-PSP bafaka izicubu zobuchopho ezibukeka njengalezo ezitholakala kubantu abanesifo i-Alzheimer. Kukhona ukulahleka kwezicubu ezindaweni eziningi zobuchopho nakwezinye izingxenye zomgogodla.
Lesi sifo sivame ukubonakala kubantu abaneminyaka engaphezu kwengama-60 ubudala, futhi sithande kakhulu emadodeni.
Izimpawu zingafaka noma yikuphi okulandelayo:
- Ukulahlekelwa ibhalansi, ukuwa okuphindaphindiwe
- Ukubambelela phambili lapho uhamba, noma ukuhamba ngokushesha
- Ukushayisa ngezinto noma kubantu
- Izinguquko ekubonakalisweni kobuso
- Ubuso obugcwele ujenga
- Izinkinga zamehlo nezokubuka ezinjengezitshudeni ezihlukene, ubunzima bokuhambisa amehlo (i-supranuclear ophthalmoplegia), ukungalawulwa kwamehlo, izinkinga zokugcina amehlo evulekile
- Kunzima ukugwinya
- Ukudlidliza, umhlathi noma amajezi obuso noma ama-spasms
- Ukuwohloka komqondo okuphakathi kuya kokulingene
- Ubuntu buyashintsha
- Ukuhamba okuhamba kancane noma okuqinile
- Ubunzima bokukhuluma, njengevolumu ephansi yezwi, engakwazi ukusho amagama ngokucacile, inkulumo ephuzayo
- Ukuqina nokunyakaza okuqinile entanyeni, maphakathi nomzimba, izingalo nemilenze
Ukuhlolwa kwesistimu yezinzwa (ukuhlolwa kwe-neurologic) kungakhombisa:
- Ukuwohloka komqondo okuya ngokuya kuba kubi
- Kunzima ukuhamba
- Ukunyakaza kwamehlo okulinganiselwe, ikakhulukazi ukunyuka phezulu naphansi
- Ukubona okujwayelekile, ukuzwa, ukuzwa, nokulawula ukunyakaza
- Ukunyakaza okuqinile nokungahambelani njengaleso seParkinson isifo
Umhlinzeki wezokunakekelwa kwempilo angenza lezi zivivinyo ezilandelayo ukukhipha ezinye izifo:
- I-Magnetic resonance imaging (MRI) ingakhombisa ukuncipha kwe-brainstem (uphawu lwe-hummingbird)
- Ukuskena kwe-PET kobuchopho kuzokhombisa izinguquko ngaphambili kobuchopho
Umgomo wokwelashwa ukulawula izimpawu. Alikho ikhambi elaziwayo le-PSP.
Imithi efana nelevodopa ingazama. Le mithi iphakamisa izinga lekhemikhali yobuchopho ebizwa nge-dopamine. I-Dopamine ibandakanyeka ekulawuleni ukunyakaza. Imithi inganciphisa ezinye izimpawu, njengezitho eziqinile noma ukuhamba kancane isikhashana. Kepha imvamisa ayisebenzi kangako njengesifo seParkinson.
Abantu abaningi abane-PSP ekugcineni bazodinga ukunakekelwa nokuqapha ubusuku nemini njengoba belahlekelwa imisebenzi yobuchopho.
Ukwelashwa kwesinye isikhathi kunganciphisa izimpawu okwesikhashana, kepha isimo sizoba sibi kakhulu. Umsebenzi wobuchopho uzokwehla ngokuhamba kwesikhathi. Ukufa kuvame ukwenzeka eminyakeni emi-5 kuya kwengu-7.
Izidakamizwa ezintsha ziyafundwa ukwelapha lesi simo.
Izinkinga ze-PSP zifaka:
- Ukuqina kwegazi emithanjeni (i-vein thrombosis ejulile) ngenxa yokuhamba okulinganiselwe
- Ukulimala kokuwa
- Ukwehluleka ukulawula umbono
- Ukulahleka kwemisebenzi yobuchopho ngokuhamba kwesikhathi
- I-pneumonia ngenxa yenkinga yokugwinya
- Ukungondleki kahle (ukungondleki)
- Imiphumela emibi evela emithini
Shayela umhlinzeki wakho uma uvame ukuwa, futhi uma unentamo / umzimba oqinile, nezinkinga zokubona.
Futhi, shayela uma othandekayo etholakele ukuthi une-PSP futhi isimo senqabe kakhulu kangangokuba awusakwazi ukunakekela umuntu ekhaya.
Ukwehla komqondo - i-dystonia ye-nuchal; Isifo se-Richardson-Steele-Olszewski; Ukukhubazeka - i-supranuclear eqhubekayo
- Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo
Isifo sikaJankovic J. Parkinson nezinye izinkinga zokuhamba. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 96.
Indlela ka-Ling H. Clinical yokukhubazeka okuqhubekayo kwe-supranuclear. J Mov Ukungezwani. 2016; 9 (1): 3-13. I-PMID: 26828211 pubmed.ncbi.nlm.nih.gov/26828211/.
I-National Institute of Neurological Disorders iwebhusayithi. Ishidi lamaqiniso eliqhubekayo lokukhubazeka kwestranuclear. www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Progressive-Supranuclear-Palsy-Fact-Sheet. Kubuyekezwe ngoMashi 17, 2020. Kufinyelelwe ngo-Agasti 19, 2020.