I-polyneuropathy engapheli yokuvuvukala

I-polyneuropathy engapheli yokuvuvukala (CIDP) ukugula okubandakanya ukuvuvukala kwemizwa nokuthukuthela (ukuvuvukala) okuholela ekulahlekelweni amandla noma ukuzwa.

I-CIDP ingenye yezimbangela zokulimazeka kwezinzwa ezingaphandle kobuchopho noma umgogodla (i-peripheral neuropathy). I-Polyneuropathy isho ukuthi kuthinteka izinzwa eziningana. I-CIDP ivame ukuthinta izinhlangothi zombili zomzimba.

I-CIDP idalwa yimpendulo yomzimba engajwayelekile. I-CIDP yenzeka lapho amasosha omzimba ehlasela isembozo se-myelin sezinzwa. Ngalesi sizathu, i-CIDP kucatshangwa ukuthi iyisifo esizimele.

Abahlinzeki bezempilo babheka i-CIDP njengohlobo olungalapheki lwe-Guillain-Barré syndrome.

Izimbangela ezithile ze-CIDP ziyahlukahluka. Ezimweni eziningi, imbangela ayikwazi ukubonwa.

I-CIDP ingavela nezinye izimo, njenge:

• I-hepatitis engapheli
• Isifo sikashukela
• Ukutheleleka ngegciwane Campylobacter jejuni
  
• I-HIV / AIDS
• Ukuphazamiseka kwesistimu yomzimba ngenxa yomdlavuza
• Isifo samathumbu esivuthayo
• Uhlelo lupus erythematosus
• Umdlavuza wohlelo lwe-lymph
• Indlala yegilo eyeqile
• Imiphumela engemihle yemithi yokwelapha umdlavuza noma i-HIV

Izimpawu zifaka noma yikuphi okulandelayo:

• Izinkinga zokuhamba ngenxa yobuthakathaka noma ukungazweli ezinyaweni
• Inkinga yokusebenzisa izingalo nezandla noma imilenze nezinyawo ngenxa yobuthakathaka
• Izinguquko zezinzwa, njengokundikindiki noma ukuncipha kokuzwa, ubuhlungu, ukuvutha, ukuhayiza, noma okunye ukuzwa okungavamile (imvamisa kuthinta izinyawo kuqala, bese izingalo nezandla)

Ezinye izimpawu ezingenzeka nge-CIDP zifaka:

• Ukunyakaza okungajwayelekile noma okungahambisani
• Izinkinga ukuphefumula
• Ukukhathala
• Ukubhonga noma ukushintsha kwezwi noma inkulumo engacacile

Umhlinzeki uzokwenza ukuhlolwa ngokomzimba futhi abuze ngezimpawu, egxile ohlelweni lwezinzwa nemisipha.

Izivivinyo ezinga-odwa zifaka:

• I-Electromyography (EMG) yokuhlola imisipha nezinzwa ezilawula imisipha
• Ukuhlolwa kwemithambo yemithambo ukuhlola ukuthi amasiginali kagesi ashesha kangakanani ukudlula enzwini
• I-nerve biopsy ukususa ucezu oluncane lwe-nerve ukuze luhlolwe
• Thepha umgogodla (ukubhoboza i-lumbar) ukuhlola uketshezi oluzungeze ubuchopho nomgogodla
• Ukuhlolwa kwegazi kungenziwa ukubheka amaprotheni athile abangela ukuhlaselwa kwamasosha omzimba ezinzwa
• Ukuhlolwa kwemisebenzi yamaphaphu ukuhlola ukuthi ukuphefumula kuyathinteka yini

Ngokuya ngesizathu esisolwayo se-CIDP, okunye ukuhlolwa, okufana nama-x-ray, ama-imaging scan, nokuhlolwa kwegazi, kungenziwa.

Umgomo wokwelashwa ukuguqula ukuhlaselwa kwezinzwa. Kwezinye izimo, izinzwa zingaphola futhi umsebenzi wazo ungabuyiselwa. Kwezinye izimo, izinzwa zonakaliswe kabi futhi azikwazi ukuphola, ngakho-ke ukwelashwa kuhloswe ukuvimbela lesi sifo ukuthi singabi sibi kakhulu.

Yikuphi ukwelashwa okunikezwayo kuncike ekutheni zimbi kangakanani izimpawu, phakathi kwezinye izinto. Ukwelashwa okunolaka kakhulu kunikezwa kuphela uma unenkinga yokuhamba, ukuphefumula, noma uma izimpawu zingakuvumeli ukuthi uzinakekele noma usebenze.

Ukwelashwa kungafaka:

• ICorticosteroids ukusiza ukunciphisa ukuvuvukala nokuqeda izimpawu
• Eminye imithi ecindezela amasosha omzimba (kwezinye izimo ezinzima)
• I-Plasmapheresis noma ukushintshaniswa kwe-plasma ukususa amasosha omzimba egazini
• I-immune globulin (IVIg) efakwa ngaphakathi, efaka ukwengeza inani elikhulu lama-antibody ku-plasma yegazi ukunciphisa umphumela wama-antibodies adala inkinga

Umphumela uyehluka. Lesi sifo singaqhubeka isikhathi eside, noma ungahle ube neziqephu zezimpawu eziphindaphindwayo. Ukululama ngokuphelele kungenzeka, kepha ukulahleka unomphela komsebenzi wezinzwa akuvamile.

Izinkinga ze-CIDP zifaka:

• Ubuhlungu
• Ukwehla okungapheli noma ukulahleka kwemizwa ezindaweni zomzimba
• Ubuthakathaka obungapheli noma ukukhubazeka ezindaweni zomzimba
• Ukulimala okuphindiwe noma okungaziwa endaweni yomzimba
• Imiphumela emibi yemithi esetshenziselwa ukwelapha lesi sifo

Shayela umhlinzeki wakho uma ulahlekelwe ukunyakaza noma ukuzwa kunoma iyiphi indawo yomzimba, ikakhulukazi uma izimpawu zakho ziba zimbi kakhulu.

Ukuvuvukala okungapheli okuqeda i-polyradiculoneuropathy; I-Polyneuropathy - ukuvuvukala okungapheli; CIDP; I-polyneuropathy engapheli yokuvuvukala; IGuillain-Barre - i-CIDP

• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo

I-Katirji B. Ukuphazamiseka kwemizwa yangaphakathi. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 107.

USmith G, Nginamahloni ME. I-peripheral neuropathies. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 392.