Parathyroid adenoma

I-parathyroid adenoma iyisilonda esingenomdlavuza (esibi) sezindlala ze-parathyroid. Izindlala ze-parathyroid zitholakala entanyeni, eduze noma ezinamathiselwe ohlangothini olungemuva lwendlala yegilo.

Izindlala ze-parathyroid ezisentanyeni zisiza ukulawula ukusetshenziswa kwe-calcium nokususwa ngumzimba. Benza lokhu ngokukhiqiza i-hormone ye-parathyroid, noma i-PTH. I-PTH isiza ukulawula amazinga e-calcium, i-phosphorus, ne-vitamin D egazini futhi ibalulekile emathanjeni aphilile.

Parathyroid adenomas kuvamile. Iningi le-adenomas ye-parathyroid ayinayo imbangela ekhonjiwe. Kwesinye isikhathi inkinga yezakhi zofuzo iyimbangela. Lokhu kuvame kakhulu uma ukuxilongwa kwenziwa ngenkathi usemncane.

Izimo ezikhuthaza izindlala ze-parathyroid ukuthi zikhule nazo zingadala i-adenoma. Lokhu kufaka phakathi:

• Izinkinga zofuzo
• Ukuthatha i-lithium yezidakamizwa
• Isifo sezinso esingalapheki

Abesifazane abangaphezu kweminyaka yobudala engama-60 basengozini enkulu kakhulu yokuthola lesi simo. Imisebe ekhanda noma entanyeni nayo inyusa ingozi.

Abantu abaningi abanazo izimpawu. Isimo sivame ukutholakala lapho ukuhlolwa kwegazi kwenziwa ngesinye isizathu sezokwelapha.

I-parathyroid adenomas iyimbangela ejwayelekile kakhulu ye-hyperparathyroidism (izindlala ezingasebenzi ngokweqile), okuholela ekukhuleni kwezinga le-calcium yegazi.Izimpawu zingafaka noma yikuphi okulandelayo:

• Ukudideka
• Ukuqunjelwa
• Ukungabi namandla (ukucobeka)
• Ubuhlungu bemisipha
• Ukucanuzela kwenhliziyo noma ukuncipha kwesifiso sokudla
• Ukuchama kaningi ebusuku
• Amathambo abuthakathaka noma ukuphuka

Ukuhlolwa kwegazi kungenziwa ukubheka amazinga we:

• I-PTH
• I-calcium
• I-Phosphorus
• Uvithamini D

Ukuhlolwa komchamo wamahora angama-24 kungenziwa ukubheka ukwanda kwe-calcium emchameni.

Ezinye izivivinyo zifaka:

• Ukuhlolwa kwesisindo samathambo
• I-kidney ultrasound noma i-CT scan (ingakhombisa amatshe ezinso noma ukubalwa)
• Izinso x-ray (zingakhombisa amatshe ezinso)
• I-MRI
• Intamo i-ultrasound
• Ukuskena kwentamo kaSestamibi (ukukhomba indawo ye-parathyroid adenoma)

Ukuhlinzwa kuyindlela yokwelashwa ejwayelekile, futhi kuvame ukwelapha isimo. Kepha, abanye abantu bakhetha kuphela ukuhlolwa njalo nomhlinzeki wabo wezokunakekelwa kwezempilo uma isimo simnene.

Ukusiza ukuthuthukisa lesi simo, umhlinzeki wakho angakucela ukuthi uyeke ukuthatha izithasiselo ze-calcium nevithamini D. Abesifazane asebedlule esikhathini sokuya esikhathini bangafuna ukuxoxa ngokwelashwa nge-estrogen.

Lapho welashwa, umbono ngokuvamile muhle.

I-osteoporosis kanye nengozi eyengeziwe yokwaphuka kwamathambo yiyona nto ekhathazeka kakhulu.

Ezinye izinkinga azijwayelekile kakhulu, kepha zingafaka:

• I-Nephrocalcinosis (i-calcium deposits ezinso enganciphisa ukusebenza kwezinso)
• I-Osteitis fibrosa cystica (ithambile, izindawo ezibuthakathaka emathanjeni)

Izinkinga ezivela ekuhlinzeni zifaka:

• Ukulimala kwethambo elilawula izwi lakho
• Ukulimala kwezindlala ze-parathyroid, ezibangela i-hypoparathyroidism (ukuntuleka kwehomoni eyanele ye-parathyroid) nezinga le-calcium ephansi

Shayela umhlinzeki wakho uma unezimpawu zalesi simo.

Hyperparathyroidism - adenoma parathyroid; Indlala ye-parathyroid esebenzayo - i-parathyroid adenoma

• Izindlala ze-Endocrine
• Nezindlala Parathyroid

Reid LM, Kamani D, Randolph GW. Ukuphathwa kokuphazamiseka kwe-parathyroid. Ku: IFlint PW, uFrancis HW, uHaughey BH, et al, eds. I-Cummings Otolaryngology: Ukuhlinzwa Kwekhanda Nentamo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2021: isahluko 123.

ISilverberg SJ, iBilezikian JP. I-hyperparathyroidism eyinhloko. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 63.

I-Thakker RV. Izindlala ze-parathyroid, i-hypercalcemia, ne-hypocalcemia. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 232.