I-Reye syndrome

I-Reye syndrome ilimala ngokuzumayo (acute) ukulimala kobuchopho nezinkinga zokusebenza kwesibindi. Lesi simo asinayo imbangela eyaziwayo.

Lesi sifo senzeke ezinganeni ezinikezwe i-aspirin lapho zinenkukhu noma umkhuhlane. I-Reye syndrome isibe yinto engavamile kakhulu. Lokhu kungenxa yokuthi i-aspirin ayisanconywa ukuthi isetshenziswe njalo ezinganeni.

Akunasizathu esaziwayo seReye syndrome. Kuvame ukubonakala ezinganeni ezineminyaka engu-4 kuye ku-12. Izimo eziningi ezenzeka ngengxibongo isezinganeni ezineminyaka engu-5 kuya kwengu-9.

Izingane ezine-Reye syndrome zigula ngokuzuma okukhulu. I-syndrome ivame ukuqala ngokuhlanza. Ingahlala amahora amaningi. Ukuhlanza kulandelwa masinyane ngokuziphatha okungacasuli nokucasula. Njengoba isimo siba sibi kakhulu, ingane ingase ingakwazi ukuhlala iphapheme futhi iqaphile.

Ezinye izimpawu zeReye syndrome:

• Ukudideka
• Imikhuba emibi
• Ukulahlekelwa ukwazi noma ikhoma
• Izinguquko zengqondo
• Isicanucanu nokuhlanza
• Ukuquleka
• Ukubekwa okungajwayelekile kwezingalo nemilenze (ukuma ngokweqile). Izingalo zelulwa ziqonde futhi ziphendukele emzimbeni, imilenze ibambe iqonde, kuthi izinzwane zikhonjwe phansi

Ezinye izimpawu ezingenzeka ngalesi sifo zifaka:

• Umbono ophindwe kabili
• Ukulahlekelwa ukuzwa
• Ukulahleka kwemisipha noma ukukhubazeka kwezingalo noma imilenze
• Ubunzima bokukhuluma
• Ubuthakathaka ezandleni noma emilenzeni

Ukuhlolwa okulandelayo kungasetshenziselwa ukuxilonga i-Reye syndrome:

• Ukuhlolwa kwamakhemikhali egazi
• Iskena se-Head CT noma se-MRI
• I-biopsy yesibindi
• Ukuhlolwa kokusebenza kwesibindi
• Ukuhlolwa kweSerum ammonia
• Thepha umgogodla

Akukho ukwelashwa okuqondile kwalesi simo. Umhlinzeki wezokunakekelwa kwempilo uzoqapha ingcindezi ebuchosheni, amagesi egazi, kanye ne-acid acid-base balance (pH).

Ukwelashwa kungafaka:

• Ukwesekwa kokuphefumula (umshini wokuphefumula ungadingeka ngesikhathi se-coma ejulile)
• Uketshezi ngo-IV ukuhlinzeka ngama-electrolyte noshukela
• Ama-steroid ukunciphisa ukuvuvukala ebuchosheni

Ukuthi umuntu wenza kahle kangakanani kuncike ebucayi banoma iyiphi ikhoma, kanye nezinye izinto.

Umphumela walabo abasinda kusiqephu esibi ungahle.

Izinkinga zingafaka:

• I-Coma
• Ukulimala kwengqondo okungapheli
• Ukuquleka

Uma kungalashwa, ukuquleka kanye nekhoma kungasongela impilo.

Iya egumbini labezimo eziphuthumayo noma shayela inombolo ephuthumayo yendawo (enjenge-911) ngokushesha uma ingane yakho ine:

• Ukudideka
• Imikhuba emibi
• Olunye ushintsho lwengqondo

Ungalokothi unikeze ingane i-aspirin ngaphandle kokuthi utshelwe ngumhlinzeki wakho.

Lapho ingane kufanele iphuze i-aspirin, qikelela ukunciphisa ingozi yengane yokuthola ukugula okunegciwane, njengomkhuhlane kanye nenkukhu. Gwema i-aspirin emasontweni ambalwa ngemuva kokuthi ingane ithole umuthi wokugoma i-varicella (chickenpox).

Qaphela: Eminye imithi ethengiswayo, njengePepto-Bismol nezinto ezinamafutha we-greengreen nazo ziqukethe ama-aspirin compounds abizwa ngokuthi ama-salicylates. UNGANIKI lezi zingane ezinomkhuhlane noma umkhuhlane.

• Izitho zohlelo lokugaya ukudla

U-Aronson JK. I-Acetylsalicylic acid. Ku: Aronson JK, ed. Imiphumela emibi kaMeyler yezidakamizwa. Umhla ka-16. I-Waltham, MA: I-Elsevier BV ;; 2016: 26-52.

UCherry JD. I-Reye syndrome. Ku: Cherry JD, Harrison GJ, Kaplan SL, Steinbach WJ, Hotez PJ, abahleli. Incwadi kaFeigin neCherry's Pediatric Infectious Diseases. Umhlaka 8. IPhiladelphia, PA: Elsevier; 2019: isahluko 50.

UJohnston MV. I-Encephalopathies. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 616.