Ukudlula ngokweqile kwenhliziyo glycoside

Ama-glycosides enhliziyo ayimithi yokwelapha ukwehluleka kwenhliziyo nokushaya kwenhliziyo okuthile okungajwayelekile. Zingelinye lamakilasi amaningana emithi esetshenziselwa ukwelapha inhliziyo nezimo ezihlobene nayo. Le mithi iyimbangela ejwayelekile yobuthi.

Ukudlula ngokweqile kwenhliziyo glycoside kwenzeka lapho othile ethatha okungaphezu kwenani elijwayelekile noma elinconywayo lalo muthi. Lokhu kungaba ngengozi noma ngenhloso.

Ama-glycosides enhliziyo atholakala ezitshalweni eziningana, kufaka phakathi amaqabunga esitshalo se-digitalis (foxglove). Lesi sitshalo singumthombo wokuqala walo muthi. Abantu abadla inani elikhulu lala maqabunga bangaba nezimpawu zokudlula ngokweqile.

Ubuthi besikhathi eside (obungapheli) bungavela kubantu abathatha ama-glycosides enhliziyo nsuku zonke. Lokhu kungenzeka uma othile eba nezinkinga zezinso noma ephelelwa amanzi emzimbeni (ikakhulukazi ezinyangeni ezishisayo zasehlobo). Le nkinga ivame ukwenzeka kubantu abadala.

Lo mbhalo ungowolwazi kuphela. UNGAYisebenzisi ukuphatha noma ukuphatha ukweqisa ngokweqile kwangempela. Uma wena noma umuntu onokweqisa ngokweqile, shayela inombolo yakho ephuthumayo yasendaweni (njenge-911), noma isikhungo sendawo sakho sobuthi singafinyelelwa ngqo ngokushayela ucingo lwasimahla lwe-Poison Help hotline (1-800-222-1222) noma yikuphi e-United States.

I-Cardiac glycoside ikhemikhali elinemiphumela enhliziyweni, esiswini, emathunjini, nakuhlelo lwemizwa. Kuyisithako esisebenzayo emithini eminingi yenhliziyo ehlukene. Kungaba nobuthi uma uthathwe ngobuningi.

Umuthi we-digoxin uqukethe ama-glycosides enhliziyo.

Ngaphandle kwesitshalo se-foxglove, ama-glycosides enhliziyo ayenzeka ngokwemvelo ezitshalweni ezinjengeLily-of-the-Valley ne-oleander, phakathi kwezinye eziningi.

Izimpawu zingase zingacaci, ikakhulukazi kubantu abadala.

Kungenzeka zenzeke ezingxenyeni ezihlukene zomzimba. Labo abane-asterisk ( *) eceleni kwabo bavame ukwenzeka kuphela uma beqisa ngokweqile.

AMEHLO, IZINDLEBE, IKHALA NOMQOLO

• Ukubona okufiphele
• Ama-Halos azungeze izinto (ophuzi, oluhlaza okotshani, omhlophe) *

ISIKHUMBA

• Ukusabela okweqile, kufaka phakathi i-Stevens-Johnson syndrome (ukuqhuma okukhulu kanye nobunzima bokugwinya nokuphefumula)
• Isifuba
• I-Rash

ISisu kanye namathumbu

• Uhudo
• Ukuphelelwa isifiso sokudla *
• Isicanucanu nokuhlanza
• Ubuhlungu besisu

INHLIZIYO NEGAZI

• Ukushaya kwenhliziyo okungajwayelekile (noma ukushaya kwenhliziyo okuhamba kancane)
• Ukushaqeka (umfutho wegazi ophansi ngokweqile)
• Ubuthakathaka

UHLELO LWE-NEERVOUS

• Ukudideka
• Ukudangala
• Ukozela
• Ukuquleka
• Ama-hallucinations *
• Ubuhlungu bekhanda
• Ukukhathazeka noma ubuthakathaka

IMPILO YENGQONDO

• Ukunganaki (ukungakhathaleli lutho)

Funa usizo lwezokwelapha ngokushesha. UNGAMENZI umuntu alahle phansi ngaphandle uma ukulawula ubuthi noma umnakekeli wezempilo ekutshela ukuthi wenze kanjalo.

Lungisa lolu lwazi:

• Iminyaka yomuntu, isisindo, nesimo
• Igama lomkhiqizo (namandla, uma kwaziwa)
• Isikhathi sigwinyiwe
• Inani ligwinyiwe

Isikhungo sakho sendawo sokulawula ubuthi singafinyelelwa ngqo ngokushayela inombolo yocingo yamahhala kazwelonke engakhokhelwa (1800-222-1222) kusuka noma yikuphi e-United States. Le nombolo yocingo kazwelonke izokuvumela ukuthi ukhulume nochwepheshe bokufaka ushevu. Bazokunikeza eminye imiyalelo.

Le yisevisi yamahhala futhi eyimfihlo. Zonke izikhungo zokulawula ubuthi e-United States zisebenzisa le nombolo kazwelonke. Kufanele ushaye uma unemibuzo mayelana nobuthi noma ukulawulwa kobuthi. Akudingeki ukuthi kube yisimo esiphuthumayo. Ungashayela nganoma yisiphi isizathu, amahora angama-24 ngosuku, izinsuku eziyi-7 ngeviki.

Thatha isiqukathi uhambe naso uye esibhedlela, uma kungenzeka.

Umhlinzeki uzolinganisa futhi aqaphe izimpawu ezibalulekile zomuntu, kufaka phakathi izinga lokushisa, ukushaya kwenhliziyo, izinga lokuphefumula, nomfutho wegazi.

Ukuhlolwa okungenziwa kufaka phakathi:

• Ukuhlolwa kwegazi nomchamo
• I-x-ray yesifuba
• I-ECG (i-electrocardiogram, noma ukulandelwa kwenhliziyo)

Ukwelashwa kungafaka:

• Uketshezi olungena ngaphakathi (olunikezwa ngomthambo)
• Imithi yokwelapha izimpawu, kufaka phakathi i-antidote (i-reversal agent)
• Amalahle avuliwe
• Ama-laxatives
• I-Pacemaker yenhliziyo yokuphazamiseka kwesigqi senhliziyo esibi
• Ukwesekwa kokuphefumula, kufaka phakathi ithubhu engena emlonyeni emaphashini futhi ixhunywe kumshini wokuphefumula (umshini wokuphefumula)
• I-renal dialysis (umshini wezinso) ezimweni ezinzima

Ukuncipha kokusebenza kwenhliziyo nokuphazamiseka kwesigqi senhliziyo kungadala imiphumela emibi. Ukufa kungenzeka, ikakhulukazi ezinganeni ezincane nakubantu abadala asebekhulile. Abantu abadala banamathuba amaningi okuthi bahlupheke ngezinkinga zobuthi besikhathi eside (obungapheli) be-glycoside yenhliziyo.

Ukweqisa izidakamizwa kwe-Digoxin; Ukweqisa izidakamizwa kwe-Digitoxin; Ukudlula ngokweqile kwe-Lanoxin; Ukweqisa izidakamizwa kwe-Purgoxin; Ukudlula ngokweqile kwe-Allocar; Ukweqisa izidakamizwa Corramedan; Ukudlula ngokweqile kwe-Crystodigin

U-Aronson JK. Ama-glycosides enhliziyo. Ku: Aronson JK, ed. Imiphumela emibi kaMeyler yezidakamizwa. Umhla ka-16. I-Waltham, MA: Elsevier; 2016: 117-157.

UCole JB. Izidakamizwa zenhliziyo. Ku: Walls RM, Hockberger RS, Gausche-Hill M, ama-eds. Imithi Ephuthumayo yaseRosen: Imiqondo kanye Nokuzijwayeza Komtholampilo. Umhlaka 9. IPhiladelphia, PA: Elsevier; 2018: isahluko 147.