Ukuhlolwa kwe-Hemoglobinuria

Ukuhlolwa kwe-Hemoglobinuria ukuhlolwa komchamo okuhlola i-hemoglobin emchameni.

Isampula yomchamo wokubamba ehlanzekile (middleream) iyadingeka. Indlela yokubamba ehlanzekile isetshenziselwa ukuvimbela amagciwane avela endondeni noma esithweni sangasese ekungeneni kusampula yomchamo. Ukuqoqa umchamo wakho, ungathola ikhithi ekhethekile yokubamba ehlanzekile kumhlinzeki wakho wezokunakekelwa kwempilo equkethe isisombululo sokuhlanza nokusula okuyinyumba. Landela imiyalo ngqo ukuze imiphumela inembile.

Akukho ukulungiselela okukhethekile okudingekile kulolu vivinyo. Uma ukuqoqwa kuthathwa kusana, kungadingeka izikhwama ezimbalwa zokuqoqa.

Ukuhlolwa kuhilela ukuchama okuvamile kuphela. Akukho ukungakhululeki.

IHemoglobin iyi-molecule enamathele kumaseli abomvu egazi. IHemoglobin isiza ukuhambisa i-oxygen ne-carbon dioxide emzimbeni.

Amangqamuzana egazi abomvu anesilinganiso sokuphila esiphakathi nezinsuku eziyi-120. Ngemuva kwalesi sikhathi, zihlukaniswa zibe izingxenye ezingenza iseli elibomvu legazi elisha. Lokhu kwephuka kwenzeka ebuchosheni, emnkantsheni, nasesibindi. Uma amangqamuzana abomvu egazi ehla emithanjeni yegazi, izingxenye zawo zihamba ngokukhululeka egazini.

Uma izinga le-hemoglobin egazini likhuphuka kakhulu, i-hemoglobin iqala ukuvela emchameni. Lokhu kubizwa ngokuthi yi-hemoglobinuria.

Lokhu kuhlolwa kungasetshenziselwa ukusiza ukuxilonga izimbangela ze-hemoglobinuria.

Imvamisa, i-hemoglobin ayiveli emchameni.

I-Hemoglobinuria ingaba umphumela wokunye kwalokhu okulandelayo:

• Ukuphazamiseka kwezinso okubizwa nge-acute glomerulonephritis
• Kushe
• Ukuchoboza ukulimala
• I-Hemolytic uremic syndrome (HUS), isifo esenzeka lapho ukutheleleka ohlelweni lokugaya ukudla kuveza izinto ezinobuthi
• Ukutheleleka kwezinso
• Isimila sezinso
• Umalaleveva
• I-paroxysmal nocturnal hemoglobinuria, isifo lapho amangqamuzana abomvu egazi ehla khona ngaphambi kwesikhathi esijwayelekile
• I-Paroxysmal cold hemoglobinuria, isifo lapho amasosha omzimba akhiqiza amasosha omzimba abhubhisa amangqamuzana abomvu egazi
• I-sickle cell anemia
• I-Thalassemia, isifo lapho umzimba wenza khona ifomu elingavamile noma inani elinganele le-hemoglobin
• I-thrombotic thrombocytopenic purpura (TTP)
• Ukusabela kokumpontshelwa
• Isifo sofuba

Umchamo - i-hemoglobin

• Isampula yomchamo

I-Landry DW, iBazari H. Indlela eya esigulini esinesifo so-renal. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 106.

URiley RS, uMcPherson RA. Ukuhlolwa okuyisisekelo komchamo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 28.