Aminoaciduria

I-Aminoaciduria inani elingajwayelekile lama-amino acid emchameni. Ama-amino acid ayizakhi zokwakha amaprotheni emzimbeni.

Isampula yomchamo wokubamba ehlanzekile iyadingeka. Lokhu kuvame ukwenziwa ehhovisi lomhlinzeki wakho wezempilo noma emtholampilo wezempilo.

Isikhathi esiningi, awudingi ukuthatha izinyathelo ezikhethekile ngaphambi kwalolu vivinyo. Qiniseka ukuthi umhlinzeki wakho uyazi yonke imithi osanda kuyisebenzisa. Uma lokhu kuhlolwa kwenziwa enganeni esencelisayo, qiniseka ukuthi umhlinzeki uyazi ukuthi imiphi imithi umama ongumhlengikazi ayiphuzayo.

Ukuhlolwa kuhilela ukuchama okuvamile kuphela.

Lokhu kuhlolwa kwenziwa ukukala amazinga e-amino acid emchameni. Kunezinhlobo eziningi zama-amino acid. Kujwayelekile ukuthi ezinye zohlobo ngalunye zitholakale emchameni. Amazinga akhuphukile ama-amino acid ngamanye angaba uphawu lwenkinga nge-metabolism.

Inani elithile likalwa nge-mmol / mol creatinine. Amanani angezansi amelela amabanga ajwayelekile kumchamo wamahora angama-24 wabantu abadala.

U-Alanine: 9 kuya ku-98

I-Arginine: 0 kuye ku-8

I-Asparagine: 10 kuye ku-65

I-Aspartic acid: 5 kuye ku-50

ICitrulline: 1 kuye ku-22

ICystine: 2 kuye ku-12

I-Glutamic acid: 0 kuya ku-21

IGlutamine: 11 kuye ku-42

IGlycine: 17 kuya ku-146

I-Histidine: 49 kuya ku-413

Isoleucine: 30 kuya ku-186

ILeucine: 1 kuye ku-9

ILysine: 2 kuya ku-16

I-Methionine: 2 kuya ku-53

I-Ornithine: 1 kuye ku-5

I-Phenylalanine: 1 kuye ku-5

Iproline: 3 kuye ku-13

I-Serine: 0 kuye ku-9

I-Taurine: 18 kuya ku-89

I-Threonine: 13 kuya ku-587

I-Tyrosine: 3 kuya ku-14

UValine: 3 kuya ku-36

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izibonelo ezingenhla zibonisa izilinganiso ezivamile zemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Ukwenyuka okuphelele komchamo ama-amino acid kungenzeka ngenxa ye:

• I-Alkaptonuria
• Isifo seCanavan
• I-cystinosis
• UCystathioninuria
• Ukungabekezelelani kwe-Fructose
• IGalactosemia
• Isifo seHartnup
• I-Homocystinuria
• Hyperammonemia
• Hyperparathyroidism
• Isifo somchamo wamaple syrup
• I-Methylmalonic acidemia
• I-myeloma eminingi
• Ukushoda kwe-Ornithine transcarbamylase
• I-Osteomalacia
• I-Propionic acidemia
• Ama-Rickets
• Uhlobo lwe-Tyrosinemia 1
• Uhlobo lwe-Tyrosinemia 2
• I-hepatitis yegciwane
• Isifo sikaWilson

Ukuhlola izinsana zamazinga akhuphukile ama-amino acid kungasiza ekutholeni izinkinga nge-metabolism. Ukwelashwa kwasekuqaleni kwalezi zimo kungavimbela izinkinga ngokuzayo.

Ama-amino acid - umchamo; Umchamo wama-amino acid

• Isampula yomchamo
• Ukuhlolwa komchamo we-Aminoaciduria

UDJ wezokudla. Ama-amino acid, ama-peptide, namaprotheni. Ku: Rifai N, ed. I-Tietz Textbook ye-Clinical Chemistry kanye ne-Molecular Diagnostics. Umhlaka 6. ISt Louis, MO: Elsevier; 2018: isahluko 28.

IKliegman RM, iSt. Geme JW, iBlum NJ, i-Shah SS, iTasker RC, iWilson KM. Amaphutha ku-metabolism yama-amino acid. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahl. 103.

URiley RS, uMcPherson RA. Ukuhlolwa okuyisisekelo komchamo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 28.