Ukuhlolwa kwegazi kwe-erythrocyte ye-Fetal-womama

Ukuhlolwa kokusatshalaliswa kwe-erythrocyte fetus-maternal kusetshenziselwa ukukala inani lamaseli abomvu engane engakazalwa egazini lowesifazane okhulelwe.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekile kulolu vivinyo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Ukungahambelani kwe-Rh yisimo esenzeka lapho uhlobo lwegazi likamama liyi-Rh-negative (Rh-) kanti uhlobo lwegazi lomntwana wakhe ongakazalwa luyi-Rh-positive (Rh +). Uma umama eyi-Rh +, noma uma bobabili abazali be-Rh-, asikho isizathu sokukhathazeka ngokungahambisani kwe-Rh.

Uma igazi lengane liyi-Rh + futhi lingena egazini likamama le-Rh, umzimba wakhe uzokhiqiza amasosha omzimba. La masosha omzimba angabuyela emuva ku-placenta futhi alimaze amangqamuzana egazi abomvu engane asakhulayo. Lokhu kungadala i-anemia emnene kuya kokubi enganeni engakazalwa.

Lokhu kuhlolwa kunquma inani legazi eliye lashintshaniswa phakathi kukamama nombungu. Bonke abesifazane abakhulelwe abane-Rh kufanele bathole lokhu kuhlolwa uma bephuma noma besengozini yokopha ngesikhathi sokukhulelwa.

Kumuntu wesifazane igazi lakhe elingu-Rh lingahambelani nosana lwakhe, lokhu kuhlolwa kusiza ekutholeni ukuthi i-Rh immune globulin (RhoGAM) okufanele ayithole kangakanani ukuvimbela umzimba wakhe ekukhiqizeni amaprotheni angajwayelekile ahlasela umntwana ongakazalwa ekukhulelweni okuzayo.

Ngenani elijwayelekile, awekho noma ambalwa amangqamuzana omntwana asesegazini likamama. Umthamo ojwayelekile weRhoGAM wanele kuleli cala.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Emiphumeleni yokuhlolwa engajwayelekile, igazi elivela enganeni engakazalwa liyavuza ekujikelezeni kwegazi likanina. Lapho amangqamuzana engane eningi eba khona, i-Rh globulin yokuvikela umzimba kakhudlwana umama okumelwe ayithole.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ibala laseKleihauer-Betke; Ukugeleza kwe-cytometry - ukusatshalaliswa kwe-erythrocyte fetus-maternal; Ukungahambelani kwe-Rh - ukusatshalaliswa kwe-erythrocyte

IChernecky CC, iBerger BJ. I-Betke-Kleihauer stain (i-fetal hemoglobin stain, i-Kleihauer-Betke stain, KB) - ukuxilonga. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelebhu kanye Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 193-194.

Ukupholisa uL, Downs T.I-Immunohematology. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 35.

Moise KJ. I-red cell alloimunization. Ku: Landon MB, Galan HL, Jauniaux ERM, et al, ama-eds. Ama-Obstetrics kaGabbe: Ukukhulelwa Okujwayelekile Nenkinga. Umhlaka 8. IPhiladelphia, PA: Elsevier; 2021: isahluko 40.