Ukuhlolwa kwegazi kwe-Alanine transaminase (ALT)

Ukuhlolwa kwegazi kwe-alanine transaminase (ALT) kukala izinga le-enzyme ALT egazini.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-ALT iyi-enzyme etholakala ezingeni eliphakeme esibindini. I-enzyme yiprotheni edala ushintsho oluthile lwamakhemikhali emzimbeni.

Ukulimala kwesibindi kubangela ukukhishwa kwe-ALT egazini.

Lokhu kuhlolwa kwenziwa ikakhulukazi nezinye izivivinyo (njenge-AST, ALP, ne-bilirubin) ukuthola nokuqapha izifo zesibindi.

Ububanzi obujwayelekile bungu-4 kuye ku-36 U / L.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola amasampula ahlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga le-ALT elandisiwe ngokuvamile liwuphawu lwesifo sesibindi. Isifo sesibindi sinamathuba amaningi kakhulu lapho amazinga ezinto ezihlolwe ngezinye izivivinyo zegazi lesibindi nawo enyukile.

Izinga le-ALT elandisiwe lingahle libangelwe ngenxa yalokhu okulandelayo:

• Ukuqubuka kwesibindi (i-cirrhosis)
• Ukufa kwezicubu zesibindi
• Isibindi sokuvuvukala esivuthayo (hepatitis)
• Insimbi eningi kakhulu emzimbeni (hemochromatosis)
• Amafutha amaningi kakhulu esibindi (isibindi esinamafutha)
• Ukuntuleka kokugeleza kwegazi kuye esibindini (isibindi ischemia)
• Isimila sesibindi noma umdlavuza
• Ukusetshenziswa kwezidakamizwa ezinobuthi esibindini
• I-Mononucleosis ("mono")
• Amapancreas avuvukile futhi avuvukile (pancreatitis)

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-Hematoma (ukuqoqa igazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-SGPT; I-serum glutamate pyruvate transaminase; I-Alanine transaminase; U-Alanine aminotransferase

IChernecky CC, iBerger BJ. I-Alanine aminotransferase (ALT, alanine transaminase, SGPT) - i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 109-110.

UPincus MR, u-Tierno PM, uGleeson E, uBowne WB, uBluth MH. Ukuhlolwa kokusebenza kwesibindi. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 21.

IPratt DS. I-chemistry yesibindi nokuhlolwa kokusebenza. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 73.