I-immunofixation - umchamo

I-urine immunofixation isivivinyo sokubheka amaprotheni angajwayelekile emchameni.

Uzodinga ukuhlinzeka ngesampula yomchamo ohlanzekile (we-middleream).

• Hlanza indawo ezungeze lapho umchamo ushiya khona umzimba. Abesilisa noma abafana kufanele basule ikhanda lomthondo. Abesifazane noma amantombazane kufanele bageze indawo ephakathi kwezindebe zesitho sangasese ngamanzi anensipho bese begeza kahle.
• Vumela inani elincane liwele esitsheni sendlu yangasese njengoba uqala ukuchama. Lokhu kusula izinto ezingangcolisa isampula. Cosha umchamo cishe o-1 kuye ku-2 (30 to 60 milliliters) womchamo esitsheni esihlanzekile osinikiwe.
• Susa isitsha ekusakazweni komchamo.
• Nikeza umhlinzeki wezempilo noma umsizi usizo.

Okosana:

• Geza kahle indawo lapho umchamo uphuma khona emzimbeni.
• Vula isikhwama sokuqoqa umchamo (isikhwama sepulasitiki esinephepha lokunamathisela ekugcineni).
• Kwabesilisa, faka wonke umthondo esikhwameni bese unamathisela ukunamathela esikhunjeni.
• Kwabesifazane, beka isikhwama phezu kwama-labia.
• Inabukeni njengenjwayelo phezu kwesikhwama esivikelekile.

Kungathatha ukuzama okungaphezu kokukodwa ukuthola isampula enganeni. Ingane esebenzayo ingahambisa isikhwama, ukuze umchamo ungene enabukeni. Hlola usana kaningi bese ushintsha isikhwama ngemuva kokuqoqwa komchamo. Khipha umchamo esikhwameni ungene esitsheni osinikezwe umhlinzeki wakho.

Hambisa isampuli ebhodini noma kumhlinzeki wakho ngokushesha okukhulu ngemuva kokuthi kwenziwe.

Azikho izinyathelo ezikhethekile ezidingekayo kulolu vivinyo.

Ukuhlolwa kuhilela ukuchama okuvamile kuphela. Akukho ukungakhululeki.

Lokhu kuhlolwa kuvame ukusetshenziselwa ukubheka ukuthi kukhona yini amaprotheni athile abizwa ngokuthi yi-monoclonal immunoglobulins. Lawa maprotheni axhunyaniswe ne-myeloma amaningi ne-Waldenström macroglobulinemia. Ukuhlolwa kwenziwa futhi ngokuhlolwa kwegazi ukubheka i-monoclonal immunoglobulin ku-serum.

Ukungabi nama-immunoglobulin amaningi emchameni kungumphumela ojwayelekile.

Ukuba khona kwamaprotheni we-monoclonal kungakhombisa:

• Umdlavuza othinta amasosha omzimba, njenge-myeloma amaningi noma i-Waldenström macroglobulinemia
• Eminye imidlavuza

I-immunofixation ifana nomchamo we-immunoelectrophoresis, kepha inganikeza imiphumela esheshayo.

UMcPherson RA, uRiley RS, uMassey HD. Ukuhlolwa kwelabhorethri yomsebenzi we-immunoglobulin kanye nokuzivikela kwamahlaya. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 46.

UTreon SP, uCastillo JJ, uHunter ZR, uMerlini G. Waldenström macroglobulinemia / lymphoplasmacytic lymphoma. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 87.