Ukuhlolwa komchamo we-5-HIAA

I-5-HIAA isivivinyo somchamo esikala inani le-5-hydroxyindoleacetic acid (5-HIAA). I-5-HIAA ingumkhiqizo wokuwohloka wehomoni ebizwa nge-serotonin.

Lokhu kuhlolwa kusitshela ukuthi umzimba ukhiqiza okungakanani u-5-HIAA. Futhi kuyindlela yokukala ukuthi ingakanani i-serotonin esemzimbeni.

Kudingeka isampula yamahora angama-24. Uzodinga ukuqoqa umchamo wakho ngaphezu kwamahora angama-24 esitsheni esihlinzekwe ilebhu. Umhlinzeki wakho wezempilo uzokutshela ukuthi ungakwenza kanjani lokhu. Landela imiyalo ngqo.

Umhlinzeki wakho uzokuyalela, uma kunesidingo, ukuthi uyeke ukuthatha imishanguzo engaphazamisa ukuhlolwa.

Imithi engakhuphula izilinganiso ze-5-HIAA ifaka i-acetaminophen (Tylenol), i-acetanilide, i-phenacetin, i-glyceryl guaiacolate (etholakala kumasiraphu amaningi wokukhwehlela), i-methocarbamol, ne-reserpine.

Imithi enganciphisa izilinganiso ze-5-HIAA ifaka i-heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines, kanye ne-tricyclic antidepressants.

Uzotshelwa ukuthi ungadli ukudla okuthile izinsuku ezintathu ngaphambi kokuhlolwa. Ukudla okungaphazamisa izilinganiso ze-5-HIAA kufaka phakathi ama-plums, uphayinaphu, ubhanana, isitshalo seqanda, utamatisi, ukwatapheya nama-walnuts.

Isivivinyo sihilela ukuchama okujwayelekile kuphela, futhi akukho ukungaphatheki kahle.

Lokhu kuhlolwa kukala izinga le-5-HIAA emchameni. Kuvame ukwenziwa ukuthola izimila ezithile kumgudu wokugaya ukudla (izicubu ze-carcinoid) nokulandela isimo somuntu.

Ukuhlolwa komchamo kungasetshenziselwa ukuxilonga isifo esibizwa nge-systemic mastocytosis kanye nezinye izicubu zehomoni.

Ububanzi obujwayelekile bungu-2 kuye ku-9 mg / 24h (10.4 kuye ku-46.8 µmol / 24h).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Imiphumela engajwayelekile ingabangelwa:

• Izimila zohlelo lwe-endocrine noma izicubu ze-carcinoid
• Ukwanda kwamaseli omzimba abizwa ngama-mast cells ezithweni eziningana (systemic mastocytosis)

Azikho izingozi ngalokhu kuhlolwa.

I-HIAA; 5-hydroxyindole acetic acid; I-Serotonin metabolite

IChernecky CC, iBerger BJ. H. Ku: Chernecky CC, Berger BJ, abahleli. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. IPhiladelphia, PA: Elsevier Saunders; 2013: 660-661.

I-Wolin EM, iJensen RT. Izimila ze-Neuroendocrine. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 219.