Ukubalwa kwe-RBC

Isibalo se-RBC ukuhlolwa kwegazi okulinganisa ukuthi unamaseli amangaki abomvu (RBCs) onawo.

Ama-RBC aqukethe i-hemoglobin, ethwala umoya-mpilo. Ukuthi izicubu zomzimba wakho zithola umoya-mpilo ongakanani kuncike ekutheni unama-RBC amangaki nokuthi asebenza kahle kangakanani.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Isibalo se-RBC cishe ngaso sonke isikhathi siyingxenye yokuhlolwa okuphelele kokubalwa kwegazi (CBC).

Ukuhlolwa kungasiza ukuxilonga izinhlobo ezahlukene ze-anemia (inani eliphansi lama-RBC) nezinye izimo ezithinta amangqamuzana abomvu egazi.

Ezinye izimo ezingadinga ukubalwa kwe-RBC yilezi:

• Izifo ezilimaza imithambo yegazi yezinso (i-Alport syndrome)
• Umdlavuza wamangqamuzana amhlophe egazi (Waldenström macroglobulinemia)
• Ukuphazamiseka lapho amangqamuzana abomvu egazi ehla ngokushesha kunokujwayelekile (i-paroxysmal nocturnal hemoglobinuria)
• Ukuphazamiseka komnkantsha wamathambo lapho umnkantsha ubuyiselwa khona yizicubu ezibomvu (myelofibrosis)

Amabanga ajwayelekile e-RBC yilezi:

• Owesilisa: amaseli ayisigidi esingu-4.7 kuya kwayi-6.1 nge-microliter ngayinye (amaseli / mcL)
• Owesifazane: amaseli ayisigidi esingu-4.2 kuya kwezi-5.4 / mcL

Amabanga angenhla yizilinganiso ezivamile zemiphumela yalezi zivivinyo. Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinombolo eziphakeme kuneziningi zama-RBCs kungenzeka ngenxa ye:

• Ukubhema ugwayi
• Inkinga ngesakhiwo senhliziyo nomsebenzi okhona lapho kuzalwa (isifo senhliziyo esizelwe)
• Ukwehluleka kohlangothi lwesokudla senhliziyo (cor pulmonale)
• Ukwehla kwamanzi emzimbeni (isibonelo, kusuka kuhudo olunzima)
• Isimila sezinso (i-renal cell carcinoma)
• Izinga le-oxygen ephansi yegazi (hypoxia)
• Ukuqhuma noma ukuqina kwamaphaphu (pulmonary fibrosis)
• Isifo somnkantsha obangela ukwanda okungajwayelekile kuma-RBCs (i-polycythemia vera)

Isibalo sakho se-RBC sizokwenyuka amasonto ambalwa lapho usendaweni ephakeme kakhulu.

Izidakamizwa ezingakhuphula isibalo se-RBC zifaka:

• Ama-Anabolic steroids
• I-Erythropoietin
• I-Gentamicin

Izinombolo ezingaphansi kokujwayelekile zama-RBCs kungenzeka ngenxa ye:

• Ukushoda kwegazi
• Ukopha
• Ukwehluleka komnkantsha wethambo (ngokwesibonelo, kusuka emisebeni, ubuthi, noma isimila)
• Ukushoda kwehomoni ebizwa nge-erythropoietin (ebangelwa yisifo sezinso)
• Ukucekelwa phansi kwe-RBC (hemolysis) ngenxa yokumpontshelwa, ukulimala kwesitsha segazi, noma enye imbangela
• Umdlavuza wegazi
• Ukungondleki
• Umdlavuza womnkantsha obizwa nge-multiple myeloma
• Insimbi encane kakhulu, ithusi, i-folic acid, uvithamini B6, noma uvithamini B12 ekudleni
• Amanzi amaningi kakhulu emzimbeni (ngokweqile)
• Ukukhulelwa

Izidakamizwa ezinganciphisa ukubalwa kwe-RBC zifaka:

• Imithi yokwelashwa ngamakhemikhali
• I-chloramphenicol namanye ama-antibiotics
• AmaHydantoins
• IMethyldopa
• Izidakamizwa ezingezona ukuvuvukala (ama-NSAID)
• I-Quinidine

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukubala kwe-Erythrocyte; Ukubalwa kwamaseli abomvu; I-anemia - isibalo se-RBC

• Ukuhlolwa kwegazi
• Izakhi ezakhiwe zegazi
• Ukuhlolwa komfutho wegazi ophakeme

IChernecky CC, iBerger BJ. Iseli elibomvu (RBC) - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2013: 961-962.

IGallagher PG. Ama-anemia we-hemolytic: ulwelwesi lwegazi elibomvu nokukhubazeka komzimba. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 152.

Little M. Anemia. Ku: Cameron P, Little M, Mitra B, Deasy C, ama-eds. Incwadi Yemithi Ephuthumayo Yabantu Abadala. Umhlaka 5. IPhiladelphia, PA: Elsevier; 2020: isahluko 13.

Kusho i-RT. Sondela kuma-anemias. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 149.