Isikhathi esithile se-thromboplastin (PTT)

Isikhathi esinqunyelwe se-thromboplastin (PTT) ukuhlolwa kwegazi okubheka ukuthi kuthatha isikhathi esingakanani ukuthi igazi ligcinwe. Kungasiza ukusho uma unenkinga yokopha noma uma igazi lakho lingagundeki kahle.

Ukuhlolwa kwegazi okuhlobene nesikhathi se-prothrombin (PT).

Kudingeka isampula yegazi. Uma uthatha noma yimiphi imithi yokuncipha kwegazi, uzobhekelwa izimpawu zokopha.

Umhlinzeki wakho wezokunakekelwa kwempilo angakutshela ukuthi uyeke ukuthatha imishanguzo okwesikhashana engathinta imiphumela yokuhlolwa. Qiniseka ukuthi utshela umhlinzeki wakho ngayo yonke imithi oyiphuzayo. Phinda utshele umhlinzeki wakho nganoma yimaphi amakhambi owathathayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Ungasidinga lesi sivivinyo uma unezinkinga zokopha noma igazi lakho lingagodoli kahle. Lapho wopha, uchungechunge lwezenzo ezibandakanya amaprotheni amaningi ahlukahlukene (izinto ezijiyisayo) zenzeka emzimbeni osiza ihlule legazi. Lokhu kubizwa ngokuthi yi-coagulation cascade. Ukuhlolwa kwe-PTT kubheka amanye amaprotheni noma izinto ezithintekayo kule nqubo futhi kukala amandla abo okusiza ukujiya kwegazi.

Ukuhlolwa kungasetshenziswa futhi ukuqapha iziguli ezithatha i-heparin, i-blood thinner.

Ukuhlolwa kwe-PTT kuvame ukwenziwa nezinye izivivinyo, njenge-prothrombin test.

Ngokuvamile, ukujiya kufanele kwenzeke kungakapheli imizuzwana engama-25 kuye kwengama-35. Uma umuntu ethatha izinciphisi zegazi, ukujiya kwegazi kuthatha izikhathi eziphindwe kabili kuya kwezingu-2 ubude.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalebhu ahlukile. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Umphumela we-PTT ongajwayelekile (omude kakhulu) nawo ungadalwa yi:

• Izinkinga zokopha, iqembu lezimo lapho kunenkinga khona ngenqubo yokuvala igazi emzimbeni
• Ukuphazamiseka lapho amaprotheni alawula ukujiya kwegazi eba ngaphezulu kokusebenzayo (kusatshalaliswa i-intravascular coagulation)
• Isifo sesibindi
• Kunzima ukumunca izakhamzimba ekudleni (malabsorption)
• Izinga eliphansi likavithamini K

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukubhoboza okuningi ukuthola imithambo
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Lokhu kuhlolwa kuvame ukwenziwa kubantu abangaba nezinkinga zokopha. Ingozi yabo yokopha iphakeme kancane kunaleyo yabantu abangenazo izinkinga zokopha.

I-APTT; PTT; Isikhathi se-thromboplastin esenziwe sasebenza

• I-vein thrombosis ejulile - ukukhipha

IChernecky CC, iBerger BJ. Isivivinyo sokufaka esikhundleni se-thromboplastin esetshenzisiwe esinqunyiwe Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 101-103.

I-Ortel TL. Ukwelashwa kwe-Antithrombotic. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 42.