Ukuhlolwa kwegazi kwamaprotheni ahlobene ne-Parathyroid

Isivivinyo se-hormone esihlobene ne-parathyroid (PTH-RP) silinganisa izinga le-hormone egazini, elibizwa ngokuthi yi-parathyroid hormone-related protein.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa behlatshwa noma bezwa nje kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kwenziwa ukuthola ukuthi ngabe izinga le-calcium ephezulu yegazi libangelwa yini ukwanda kwamaprotheni ahlobene ne-PTH.

Awekho amaprotheni afana ne-PTH afana (noma amancane) ajwayelekile.

Abesifazane abancelisayo bangaba namanani amaprotheni ahlobene ne-PTH.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga elikhulisiwe lamaprotheni ahlobene ne-PTH anezinga eliphakeme le-calcium egazini ngokuvamile libangelwa umdlavuza.

Amaprotheni ahlobene ne-PTH angakhiqizwa yizinhlobo eziningi zomdlavuza, kufaka phakathi lezo zamaphaphu, isifuba, ikhanda, intamo, isinye, nama-ovari. Cishe kokuthathu kokuthathu kwabantu abanomdlavuza abanesilinganiso esiphakeme se-calcium, izinga eliphezulu lamaprotheni ahlobene ne-PTH ayimbangela. Lesi simo sibizwa ngokuthi yi-humoral hypercalcemia ye-malignancy (HHM) noma i-paraneoplastic hypercalcemia.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-PTHrp; I-peptide ehlobene ne-PTH

I-Bringhurst FR, iDemay MB, iKronenberg HM. AmaHormoni nokuphazamiseka kwesimo semaminerali. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 28.

I-Thakker RV. Izindlala ze-parathyroid, i-hypercalcemia ne-hypocalcemia. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 232.