Ukuhlolwa kwehomoni yokukhula

Ukuhlolwa kwe-hormone yokukhula kukala inani le-hormone yokukhula egazini.

Indlala ye-pituitary yenza i-hormone yokukhula, ebangela ukuthi ingane ikhule. Le ndlala itholakala ezansi kobuchopho.

Kudingeka isampula yegazi.

Umhlinzeki wakho wezokunakekelwa kwempilo angakunika imiyalelo ekhethekile mayelana nokuthi yini ongayidla noma ongayidli ngaphambi kokuhlolwa.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Le hormone ingahlolwa uma ngabe iphethini yokukhula komuntu ingajwayelekile noma uma kusolwa esinye isimo.

• I-hormone yokukhula eningi kakhulu (GH) ingadala amaphethini wokukhula ngokungajwayelekile. Kubantu abadala, lokhu kubizwa nge-acromegaly. Ezinganeni, kubizwa ngokuthi yi-gigantism.
• I-hormone yokukhula encane kakhulu ingadala ukukhula kancane noma okucaba kokukhula ezinganeni. Kubantu abadala, kwesinye isikhathi kungadala ushintsho emandleni, emisipheni, emazingeni e-cholesterol, nasemandleni amathambo.

Ukuhlolwa kwe-GH kungasetshenziswa futhi ukuqapha impendulo ekwelashweni kwe-acromegaly.

Ububanzi obujwayelekile bezinga le-GH ngokuvamile:

• Kwabesilisa abadala - ama-nanograms angu-0,4 kuya kwayi-10 ngemililitha (ng / ml), noma ama-picomoles ayi-18 kuye kwangama-44 ngelitha ngalinye (pmol / L)
• Kwabesifazane abadala - 1 kuya ku-14 ng / mL, noma u-44 kuye ku-616 pmol / L
• Ezinganeni - 10 kuya ku-50 ng / mL, noma ku-440 kuya ku-2200 pmol / L

I-GH ikhishwa ngama-pulses. Usayizi nobude be-pulses buyehluka ngesikhathi sosuku, ubudala, nobulili. Kungakho izilinganiso ze-GH ezingahleliwe zivame ukuba lusizo. Izinga eliphakeme lingajwayelekile uma igazi likhishwe ngesikhathi sokushaya. Izinga eliphansi lingajwayelekile uma igazi likhishwe ngasekupheleni kwenhliziyo. I-GH ilusizo kakhulu lapho ilinganiswa njengengxenye yokuhlolwa kokukhuthaza noma ukucindezela.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga eliphakeme le-GH lingakhombisa:

• I-GH eningi kakhulu kubantu abadala, ibizwa nge-acromegaly. (Kwenziwa ukuhlolwa okukhethekile ukuqinisekisa lokhu kutholakala kwesifo.)
• Ukukhula okungajwayelekile ngenxa ye-GH eyeqile ebuntwaneni, ebizwa nge-gigantism. (Kwenziwa ukuhlolwa okukhethekile ukuqinisekisa lokhu kutholakala kwesifo.)
• Ukumelana ne-GH.
• Isimila sesibeletho.

Izinga eliphansi le-GH lingakhombisa:

• Ukukhula kancane kuqashelwe ebuntwaneni noma ebuntwaneni, kubangelwa amazinga aphansi e-GH. (Kwenziwa ukuhlolwa okukhethekile ukuqinisekisa lokhu kutholakala kwesifo.)
• I-Hypopituitarism (umsebenzi ophansi wendlala ye-pituitary).

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa kwe-GH

• Ukukhula kwe-hormone stimulation test - uchungechunge

U-Ali O. Hyperpituitarism, ubude obude, kanye nama-syndromes akhule ngokweqile. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 576.

IChernecky CC, iBerger BJ. I-hormone yokukhula (i-somatotropin, i-GH) ne-hormone ekhulula ama-hormone (GHRH) - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. IPhiladelphia, PA: Elsevier Saunders; 2013: 599-600.

ICooke DW, iDivall SA, uRadovick S. Ukukhula okujwayelekile nokungajwayelekile ezinganeni. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 25.