Ukuhlolwa kwegazi leProlactin

I-prolactin iyi-hormone ekhishwe yindlala ye-pituitary. Ukuhlolwa kweprolactin kukala inani leprolactin egazini.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Iprolactin iyi-hormone ekhishwe yindlala ye-pituitary. I-pituitary iyindlala encane engxenyeni yobuchopho. Ilawula ukulingana komzimba kwamahomoni amaningi.

Iprolactin ivuselela ukukhula kwamabele nokukhiqizwa kobisi kwabesifazane. Awukho umsebenzi ojwayelekile owaziwayo we-prolactin emadodeni.

I-prolactin ivame ukulinganiswa lapho kubhekwa izicubu ze-pituitary nembangela ye:

• Ukukhiqizwa kobisi lwebele olungahlobene nokubeletha (galactorrhea)
• Ukwehla kwe-sex drive (libido) kwabesilisa nabesifazane
• Izinkinga zokwakhiwa emadodeni
• Ayikwazi ukukhulelwa (ukungazali)
• Isikhathi esingajwayelekile noma esingekho sokuya esikhathini (amenorrhea)

Amanani ajwayelekile weprolactin yilawa:

• Abesilisa: ngaphansi kuka-20 ng / mL (425 µg / L)
• Abesifazane abangakhulelwe: ngaphansi kuka-25 ng / mL (25 µg / L)
• Abesifazane abakhulelwe: 80 kuya ku-400 ng / mL (80 kuya ku-400 µg / L)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Abantu abanezimo ezilandelayo bangaba namazinga aphezulu e-prolactin:

• Ukulimala odongeni lwesifuba noma ukucasuka
• Isifo sendawo yobuchopho esibizwa nge-hypothalamus
• Indlala yegilo ayiyenzi ngokwanele i-hormone yegilo (hypothyroidism)
• Isifo sezinso
• I-pituitary tumor eyenza iprolactin (prolactinoma)
• Ezinye izicubu zezifo kanye nezifo endaweni ye-pituitary
• Ukususwa okungajwayelekile kwama-molecule we-prolactin (macroprolactin)

Imithi ethile ingakhuphula nezinga leprolactin, kufaka phakathi:

• Izidambisi
• Ama-butyrophenones
• Ama-Estrogens
• Ama-H2 blocker
• IMethyldopa
• I-Metoclopramide
• Imithi ye-opiate
• Ama-phenothiazines
• Hlanganisa kabusha
• I-Risperidone
• I-Verapamil

Imikhiqizo yensangu nayo ingakhuphula izinga leprolactin.

Uma izinga lakho le-prolactin liphezulu, isivivinyo singaphindwa ekuseni ngakusasa ngemuva kokuzila kwehora eli-8.

Okulandelayo kungakhuphula okwesikhashana amazinga e-prolactin:

• Ukucindezeleka ngokomzwelo noma ngokomzimba (ngezikhathi ezithile)
• Ukudla okuphezulu kwamaprotheni
• Ukukhuthaza kakhulu amabele
• Ukuhlolwa kwamabele kwakamuva
• Ukuzivocavoca kwakamuva

Ukuhunyushwa kokuhlolwa kwegazi okuphezulu ngokungajwayelekile kuyinkimbinkimbi. Ezimweni eziningi, umhlinzeki wakho uzodinga ukukudlulisela ku-endocrinologist, udokotela ogxile ezinkingeni zehomoni.

Kunobungozi obuncane bokuthathwa kwegazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-PRL; Ukuhlolwa kweGalactorrhea - iprolactin; Ukuzala - ukuhlolwa kweprolactin; I-amenorrhea - ukuhlolwa kweprolactin; Ukuvuza kwesifuba - ukuhlolwa kweprolactin; Prolactinoma - ukuhlolwa kweprolactin; Ukuhlolwa kwe-pituitary tumor - iprolactin test

IChernecky CC, iBerger BJ. Iprolactin (iprolactin yomuntu, i-HPRL) - i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. IPhiladelphia, PA: Elsevier Saunders; 2013: 910-911.

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

UKaiser U, Ho K. Pituitary physiology kanye nokuhlolwa kokuxilongwa. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 8.