I-MIBG scintiscan

I-MIBG scintiscan uhlobo lokuhlolwa kwe-imaging. Isebenzisa into enemisebe (ebizwa ngokuthi i-tracer). Isithwebuli sithola noma siqinisekise ubukhona be-pheochromocytoma ne-neuroblastoma. Lezi yizinhlobo zamathumba ezithinta izicubu zemizwa.

I-radioisotope (MIBG, iodine-131-meta-iodobenzylguanidine, noma iodine-123-meta-iodobenzylguanidine) ijojowe emthanjeni. Le nhlanganisela inamathela kumaseli athile wesimila.

Uzoba nokuskena kamuva ngalolo suku noma ngosuku olulandelayo. Kule ngxenye yesivivinyo, ulala etafuleni ngaphansi kwengalo yesithwebuli. Isisu sakho siskeniwe. Ungadinga ukubuyela ukuskena okuphindaphindiwe izinsuku ezi-1 kuye kwezi-3. Ukuskena ngakunye kuthatha amahora awu-1 kuya kwangu-2.

Ngaphambi noma ngesikhathi sokuhlolwa, unganikezwa ingxube ye-iodine. Lokhu kuvimbela indlala yakho yegilo ekungeniseni i-radioisotope eningi kakhulu.

Uzodinga ukusayina ifomu lokuvuma unolwazi. Uzocelwa ukuthi ugqoke ingubo yasesibhedlela noma izingubo ezingakulungele. Uzodinga ukususa ubucwebe noma izinto zensimbi ngaphambi kokuskena ngakunye. Izidakamizwa eziningi ziphazamisa isivivinyo. Buza umhlinzeki wakho wezokunakekelwa kwempilo ukuthi imiphi imithi yakho ejwayelekile ongayidinga ukuyeka ukuyiphuza ngaphambi kokuhlolwa.

Uzozwa inaliti ebukhali lapho okokusebenza kujovwa. Itafula lingabanda noma libe nzima. Kufanele ulale unganyakazi ngesikhathi sokuskena.

Lokhu kuhlolwa kwenziwa ukusiza ukuxilonga i-pheochromocytoma. Kwenziwa lapho ukuskena kwe-CT esiswini noma ukuskena kwe-MRI esiswini kunganikezi impendulo eqondile. Ibuye isetshenziselwe ukusiza ukuxilonga i-neuroblastoma futhi ingasetshenziselwa izicubu ze-carcinoid.

Azikho izimpawu zesimila.

Imiphumela engajwayelekile ingakhombisa:

• Pheochromocytoma
• Ama-endocrine neoplasia amaningi (AMADODA) II
• Isimila se-carcinoid
• I-Neuroblastoma

Kukhona ukuvezwa kwemisebe evela kwi-radioisotope. Imisebe evela kule radioisotope iphakeme kuneminye eminingi. Ungadinga ukuthatha izinyathelo zokuqapha ezengeziwe ezinsukwini ezimbalwa ngemuva kokuhlolwa. Umhlinzeki wakho uzokutshela ukuthi yiziphi izinyathelo okufanele uzenze.

Ngaphambi noma ngesikhathi sokuhlolwa, unganikezwa isisombululo se-iodine. Lokhu kuzogcina indlala yakho yegilo ingamunci iodine eningi. Imvamisa abantu bathatha i-potassium iodide usuku olungu-1 ngaphambi kwezinsuku eziyisithupha ngemuva. Lokhu kuvimbela i-thyroid ekuthatheni i-MIBG.

Lokhu kuhlolwa AKUFANELE kwenziwe kwabesifazane abakhulelwe. Imisebe ingadala ingozi enganeni engakazalwa.

Ukucabanga kwe-adrenal medullary; I-Meta-iodobenzylguanidine scintiscan; I-Pheochromocytoma - MIBG; I-Neuroblastoma - MIBG; I-Carcinoid MIBG

• Umjovo we-MIBG

UBleeker G, Tytgat GAM, Adam JA, et al. I-123I-MIBG scintigraphy kanye ne-18F-FDG-PET imaging yokuthola i-neuroblastoma. Isikhungo sedatha yeCochrane Rev. 2015; (9): CDC009263. I-PMID: 26417712 pubmed.ncbi.nlm.nih.gov/26417712/.

ICohen DL, iFishbein L.Umfutho wegazi ophezulu wesibili: i-pheochromocytoma ne-paraganglioma. Ku: Bakris GL, Sorrentino MJ, ama-eds. Umfutho wegazi ophezulu: Umngane Wezifo Zenhliziyo zeBraunwald. 3rd ed. IPhiladelphia, PA: Elsevier; 2018: isahluko 15.

Izicubu ze-Oberg K. Neuroendocrine kanye nokuphazamiseka okuhlobene. KuMelmed S, Auchus RJ, Goldfine AB, Koenig RJ, et al. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 45.

Yeh MW, uLivhits MJ, uDuh Q-Y. Izindlala ze-adrenal. Ku: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. ISabiston Incwadi Yokuhlinzwa. Umhla ka-20. IPhiladelphia, PA: Elsevier; 2017: isahluko 39.