Ukuhlolwa kweTensilon

Ukuhlolwa kweTensilon kuyindlela yokusiza ukuxilonga i-myasthenia gravis.

Umuthi obizwa nge-Tensilon (obizwa nangokuthi i-edrophonium) noma umuthi we-dummy (i-placebo engasebenzi) unikezwa phakathi nalolu vivinyo. Umhlinzeki wokunakekelwa kwezempilo unikeza umuthi ngomunye wemithambo yakho (ngemithambo yegazi, nge-IV). Unganikezwa nomuthi obizwa nge-atropine ngaphambi kokuthola iTensilon ukuze ungazi ukuthi uthola lo muthi.

Uzocelwa ukuthi wenze ukunyakaza kwemisipha kaninginingi, njengokuwela nokunqamula imilenze yakho noma ukuvuka endaweni yokuhlala esihlalweni. Umhlinzeki uzohlola ukuthi ngabe iTensilon ithuthukisa amandla akho emisipha. Uma unobuthakathaka beso noma imisipha yobuso, umphumela weTensilon kulokhu nawo uzobhekwa.

Ukuhlolwa kungaphindwa futhi ungaba nokunye ukuhlolwa kweTensilon ukusiza ukutshela umehluko phakathi kwe-myasthenia gravis nezinye izimo.

Akukho ukulungiselela okukhethekile okudingeka njalo. Landela imiyalo yomhlinzeki wakho mayelana nokuthi uzilungiselela kanjani.

Uzozwa ukubhoboza okucijile njengoba kufakwa inaliti ye-IV. Isidakamizwa singadala umuzwa wokudonswa yisisu noma umuzwa omncane wokukhuphuka kwenhliziyo, ikakhulukazi uma i-atropine inganikezwa kuqala.

Ukuhlolwa kuyasiza:

• Thola i-myasthenia gravis
• Tshela umehluko phakathi kwe-myasthenia gravis nezinye izimo ezifanayo zobuchopho nezesistimu yezinzwa
• Gada ukwelashwa ngezidakamizwa zomlomo ze-anticholinesterase

Ukuhlolwa kungenziwa futhi ngezimo ezinjenge-Lambert-Eaton syndrome. Lesi yisifo lapho ukuxhumana okuyiphutha phakathi kwezinzwa nemisipha kuholela ebuthakathakeni bemisipha.

Kubantu abaningi abane-myasthenia gravis, ubuthakathaka bemisipha buzothuthuka ngemuva nje kokuthola iTensilon. Ukuthuthuka kuthatha imizuzu embalwa kuphela. Kwezinye izinhlobo ze-myasthenia, iTensilon ingenza ubuthakathaka bube nzima kakhulu.

Lapho lesi sifo siba sibi ngokwanele ukuthi singadinga ukwelashwa (inkinga ye-myasthenic), kuba nokuthuthuka okuncane emandleni emisipha.

Lapho kunokudlula ngokweqile kwe-anticholinesterase (inkinga ye-cholinergic), iTensilon izokwenza umuntu abe buthakathaka nakakhulu.

Umuthi osetshenziswe ngesikhathi sokuhlolwa ungadala imiphumela emibi, kufaka phakathi ukuquleka noma ukwehluleka ukuphefumula. Kungakho ukuhlolwa kwenziwa umhlinzeki esimweni sezokwelapha.

Ukuhlolwa kwe-Myasthenia gravis - tensilon

• Ukukhathala kwemisipha

IChernecky CC, iBerger BJ. Ukuhlolwa kweTensilon - ukuxilonga. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 1057-1058.

ISanders DB, iGuptill JT. Ukuphazamiseka kokudluliswa kwe-neuromuscular. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 109.