Ukuhlolwa kuka-H pylori

I-Helicobacter pylori (H pylori) ibhaktheriya (igciwane) elibhekele iningi lesisu (esiswini) kanye nezilonda ze-duodenal nezimo eziningi zokuvuvukala kwesisu (i-gastritis engapheli).

Kunezindlela eziningana ongazihlolela zona H pylori ukutheleleka.

Ukuhlolwa Kokuphefumula (I-Carbon Isotope-urea Breath Test, noma i-UBT)

• Kuze kube amasonto ama-2 ngaphambi kokuhlolwa, udinga ukuyeka ukuthatha ama-antibiotic, imithi ye-bismuth efana ne-Pepto-Bismol, ne-proton pump inhibitors (PPIs).
• Ngesikhathi sokuhlolwa, ugwinya into ekhethekile ene-urea. I-Urea ingumkhiqizo odoti owenziwa ngumzimba njengoba wephula amaprotheni. I-urea esetshenziswe esivivinyweni yenziwe ngemisebe engeyona ingozi.
• Uma H pylori akhona, amabhaktheriya aguqula i-urea ibe yi-carbon dioxide, etholwa futhi iqoshwe ekuphefumuleni kwakho okuphefumulayo ngemuva kwemizuzu eyi-10.
• Lokhu kuhlolwa kungakhomba cishe bonke abantu abaye H pylori. Ingasetshenziswa futhi ukubheka ukuthi ukutheleleka kuselashwe ngokuphelele yini.

Ukuhlolwa Kwegazi

• Ukuhlolwa kwegazi kusetshenziselwa ukukala ama-antibody ku- H pylori. Ama-antibody amaprotheni enziwa amasosha omzimba womzimba lapho ethola izinto eziyingozi njengamagciwane.
• Ukuhlolwa kwegazi kwe- H pylori ungasho kuphela uma umzimba wakho unakho H pylori amasosha omzimba. Ayikwazi ukusho ukuthi unesifo esikhona manje noma ukuthi usunesikhathi esingakanani unaso. Lokhu kungenxa yokuthi ukuhlolwa kungaba ne-positive iminyaka, noma ngabe ukutheleleka kuyelapheka. Ngenxa yalokhu, ukuhlolwa kwegazi akukwazi ukusetshenziselwa ukubona ukuthi ngabe ukutheleleka kuphulukisiwe yini ngemuva kokwelashwa.

Ukuhlolwa kwe-Stool

• Ukuhlolwa kwendle kungathola imikhondo ye- H pylori endleni.
• Lokhu kuhlola kungasetshenziselwa ukuxilonga ukutheleleka nokuqinisekisa ukuthi selaphekile ngemuva kokwelashwa.

Isidumbu

• Isampula lezicubu, elibizwa ngokuthi yi-biopsy, lithathwa ulwelwesi lwesisu. Le yindlela enembile kunazo zonke yokutshela uma une- H pylori ukutheleleka.
• Ukususa isampula lezicubu, unenqubo ebizwa nge-endoscopy. Inqubo yenziwa esibhedlela noma esikhungweni sokugula.
• Imvamisa, i-biopsy yenziwa uma i-endoscopy iyadingeka kwezinye izizathu. Izizathu zifaka ukuxilonga isilonda, ukwelapha ukopha, noma ukuqiniseka ukuthi awukho umdlavuza.

Ukuhlola kuvame ukwenziwa ukuxilonga H pylori ukutheleleka:

• Uma njengamanje unesilonda esiswini noma se-duodenal
• Ukube ubunesisu noma isilonda esisesiswini esikhathini esidlule, futhi awuzange uhlolwe H pylori
• Ngemuva kokwelashwa kwe- H pylori ukutheleleka, ukuqinisekisa ukuthi awekho amabhaktheriya

Ukuhlola kungenziwa futhi uma udinga ukuthatha ibuprofen yesikhathi eside noma eminye imithi ye-NSAID. Umhlinzeki wakho wezokunakekelwa kwempilo angakutshela okuningi.

Ukuhlolwa kungabuye kunconyelwe isimo esibizwa nge-dyspepsia (indigestion). Lokhu ukungakhululeki okuphezulu kwesisu. Izimpawu zifaka phakathi umuzwa wokugcwala noma ukushisa, ukushisa, noma ubuhlungu endaweni ephakathi kwenkaba nengxenye engezansi yesifuba sesifuba ngesikhathi sokudla noma ngemuva kokudla. Ukuhlolela i- H pylori ngaphandle kwe-endoscopy kuvame ukwenziwa kuphela uma ukungakhululeki kusha, umuntu usemncane kuno-55, futhi azikho ezinye izimpawu.

Imiphumela ejwayelekile isho ukuthi alukho uphawu lokuthi une H pylori ukutheleleka.

Imiphumela engajwayelekile isho ukuthi une- H pylori ukutheleleka. Umhlinzeki wakho uzoxoxa nawe ngokwelashwa.

Isifo se-Peptic ulcer - H pylori; I-PUD - H pylori

Ikhava ye-TL, iBlaser MJ. I-Helicobacter pylori nezinye izinhlobo ze-Helicobacter esiswini. Ku: Bennett JE, Dolin R, Blaser MJ, ama-eds. Mandell, Douglas, kanye neBennett's Principles and Practice of Infectious Diseases. Umhlaka 9. IPhiladelphia, PA: Elsevier; 2020: isahluko 217.

UMorgan DR, uCrowe SE. Ukutheleleka kwe-Heliobacter pylori. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 51.

USiddiqi HA, uSalwen MJ, uShaikh MF, uBowne WB. Ukuxilongwa kwelabhoratri kokuphazamiseka kwamathumbu kanye ne-pancreatic. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 22.