I-insulin Glargine (imvelaphi ye-rDNA) Injection

-Delile

• Ngaphambi kokusebenzisa i-insulin glargine,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• I-insulin glargine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• I-insulini glargine overdose ingenzeka uma usebenzisa i-insulin glargine ngokweqile noma uma usebenzisa inani elifanele le-insulin glargine kodwa udle okuncane kunokujwayelekile noma uvivinye umzimba kunokujwayelekile. I-insulin glargine overdose ingadala i-hypoglycemia. Uma unezimpawu ze-hypoglycemia, landela imiyalo kadokotela wakho yokuthi yini okufanele uyenze uma uba ne-hypoglycemia. Ezinye izimpawu zokudlula ngokweqile:

I-insulin glargine isetshenziselwa ukwelapha isifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini). Ibuye isetshenziselwe ukwelapha abantu abanesifo sikashukela sohlobo lwe-2 (isimo lapho umzimba ungasebenzisi i-insulin ngokwejwayelekile futhi, ngakho-ke, awukwazi ukulawula inani likashukela egazini) abadinga i-insulin ukulawula isifo sikashukela. Kubantu abanesifo sikashukela sohlobo 1, i-insulin glargine kufanele isetshenziswe nolunye uhlobo lwe-insulin (i-insulin esebenza okwesikhashana). Kubantu abanesifo sikashukela sohlobo 2, i-insulin glargine nayo ingasetshenziswa nolunye uhlobo lwe-insulin noma ngemithi yomlomo yesifo sikashukela. I-insulin glargine yinguqulo esebenza isikhathi eside, eyenziwe ngumuntu ye-insulin yomuntu. I-insulin glargine isebenza ngokufaka esikhundleni se-insulin evame ukukhiqizwa ngumzimba nangokusiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. Iphinde ime isibindi ekukhiqizeni ushukela owengeziwe.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-insulini glargine iza njengesisombululo (uketshezi) ukujova ngomgogodla (ngaphansi kwesikhumba). Kujova kanye ngosuku. Kufanele usebenzise i-insulin glargine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-insulin glargine njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Ungalokothi usebenzise i-insulin glargine uma unezimpawu ze-hypoglycemia (ushukela ophansi wegazi) noma uma uhlolisise ushukela wegazi lakho wakuthola kuphansi.

I-insulin glargine ilawula isifo sikashukela kepha ayiselaphi. Qhubeka nokusebenzisa i-insulin glargine noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa i-insulin glargine ngaphandle kokukhuluma nodokotela wakho. Ungashintsheli kolunye uhlobo noma uhlobo lwe-insulin noma ushintshe umthamo wanoma yiluphi uhlobo lwe-insulin oyisebenzisayo ngaphandle kokukhuluma nodokotela wakho. Njalo hlola ilebula le-insulin ukuze uqiniseke ukuthi uthola uhlobo olulungile lwe-insulin ekhemisi.

I-insulini glargine iza ngezimbiza nasezibayeni zokufaka okuqukethe ama-cartridges emithi. Qiniseka ukuthi uyazi ukuthi uluhlobo luni lwesitsha i-insulin glargine yakho engenayo nokuthi iziphi ezinye izinto, njengezinaliti, imijovo, noma izibaya, ozodinga ukujova umuthi wakho.

Uma i-insulin glargine yakho ifika ezimbizeni, kuzodingeka usebenzise imijovo ukujova umthamo wakho. Cela udokotela wakho noma usokhemisi ukuthi akubonise ukuthi ungayifaka kanjani i-insulin glargine usebenzisa isipontsho. Buza udokotela noma usokhemisi wakho uma unemibuzo ngohlobo lomjovo okufanele uwusebenzise.

Uma i-insulin glargine yakho iza ezibayeni, qiniseka ukuthi ufunda futhi uqonde iziyalezo zomkhiqizi. Cela udokotela wakho noma usokhemisi ukuthi akubonise ukuthi uyisebenzisa kanjani ipeni. Landela izinkomba ngokucophelela, futhi njalo wenze ukuhlolwa kokuphepha ngaphambi kokusetshenziswa.

Ungalokothi usebenzise izinaliti noma imijovo futhi ungalokothi wabelane ngezinaliti, imijovo noma izibaya. Uma usebenzisa ipeni le-insulin, hlala njalo ngenaliti ngemuva nje kokujova umthamo wakho. Lahla izinaliti nemijovo esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Musa ukuxuba i-insulin glargine futhi ungahlanganisi i-insulin glargine nanoma yiluphi olunye uhlobo lwe-insulin.

Ungajova i-insulin glargine engalweni, ethangeni noma esiswini. Ungalokothi ufake i-insulin glargine emthanjeni noma emisipheni. Shintsha (jikelezisa) indawo yokujova ngaphakathi kwendawo ekhethiwe ngomthamo ngamunye; zama ukugwema ukujova isiza esifanayo kaningi ngaphezu kwesisodwa njalo emavikini ayi-1 kuye kwayi-2.

Njalo bheka i-insulin glargine yakho ngaphambi kokuyijova. Kufanele icace futhi ingenambala. Ungayisebenzisi i-insulin glargine yakho uma inemibala, inamafu, noma iqukethe izinhlayiya eziqinile, noma uma usuku lokuphelelwa yisikhathi ebhodleleni seludlulile.

Ungayisebenzisi i-insulin glargine kwiphampu yangaphandle ye-insulin.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-insulin glargine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-insulin (Humulin, Novolin, abanye), noma iziphi izithako ze-insulin glargine, noma omunye umuthi. Buza usokhemisi wakho noma hlola imininingwane yesiguli somkhiqizi ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyiphuzayo. Qinisekisa ukusho noma yikuphi kokulandelayo: i-albuterol (i-Accuneb, i-Proair, i-Proventil, abanye); imishanguzo kadokotela neyokungabhalisi equkethe utshwala; i-angiotensin-converting enzyme inhibitors (i-ACE inhibitors) efana ne-benazepril (iLotensin, eLotrel), i-captopril, i-enalapril (i-Epaned, i-Vasotec, ngesi-Vaseretic), i-fosinopril, i-lisinopril (ePrinzide, e-Zestoretic), moexipril, i-perindopalia i-quinapril (i-Accupril, nge-Accuretic, ngesi-Quinaretic), i-ramipril (i-Altace), ne-trandolapril (i-Mavik, eTarka); ama-angiotensin receptor blockers (ama-ARB) afana ne-azilsartan (Edarbi, e-Edarbyclor), amakhandlela (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), telmisartan Micard eMicardis HCT, eTwynsta), i-valsartan (iDiovan, eDiovan HCT, e-Exforge); i-antipsychotic efana ne-clozapine (Clozaril, Fazaclo, Versacloz) ne-olanzapine (iZyprexa, e-Symbyax); ama-beta-blocker anjenge-atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kanye nepropranolol (Hemangeol, Inderal LA, Innopran XL); imithi ethile yokwehlisa i-cholesterol efana ne-fenofibrate (Antara, Lipofen, Triglide), gemfibrozil (Lopid), ne-niacin (Niacor, Niaspan); clonidine (Catapres, Catapres-TTS, Kapvay, eClorpres, abanye); i-danazol; i-disopyramide (iNorpace); isisu (‘amaphilisi amanzi’); ama-estrogens; i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, ku-Symbyax); i-glucagon; i-guanethidine (ayitholakali e-U.S.); Ama-HIV protease inhibitors afaka i-atazanavir (Reyataz), indinavir (Crixivan), lopinavir (eKaletra), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra, e-Viekira Pak), ne-saquinavir (i-Invirase); ukwelashwa okubuyisela ama-hormone (amaphilisi okulawula ukubeletha, amabala, izindandatho, imijovo, noma okufakelwa); i-isoniazid (iLaniazid, eRifamate, eRifater); i-lithium (i-Lithobid); imithi yesifuba somoya nemikhuhlane; imithi yokugula ngengqondo kanye nesicanucanu; i-monoamine oxidase (MAO) inhibitors kufaka phakathi i-isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ne-tranylcypromine (iParnate); i-octreotide (iSandostatin); izinto zokuvimbela inzalo ngomlomo (amaphilisi okuvimbela inzalo); imithi yomlomo yesifo sikashukela efana ne-pioglitazone (Actos, e-Actoplus Met, e-Oseni, abanye) kanye ne-rosiglitazone (Avandia); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); ipentamidine (NebuPent, Pentam); i-pentoxifylline (Pentoxil); i-pramlintide (Symlin); i-propoxyphene (ayitholakali e-U.S.); qamba kabusha; ubuhlungu be-salicylate buqeda njenge-aspirin, i-choline magnesium trisalicylate, i-choline salicylate, i-diflunisal, i-magnesium salicylate (i-Doan's, abanye), ne-salsalate; somatropin (Genotropin, Humatrope, Nutropin, Serostim, abanye); i-sulfa antibiotic; i-terbutaline; nemithi yegilo. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nomonakalo wezinzwa obangelwa yisifo sikashukela, ukwehluleka kwenhliziyo, amazinga aphansi egazi e-potassium; noma yiziphi ezinye izimo zezokwelapha, kufaka phakathi inhliziyo, isibindi noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-insulin glargine, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-insulin glargine.
• utshwala bungadala ushintsho kushukela wegazi. Buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi usebenzisa i-insulin glargine.
• buza udokotela wakho ukuthi wenzeni uma ugula, uba nengcindezi engajwayelekile, noma ushintsha indlela odla ngayo, ukuzivocavoca umzimba noma uhlelo lomsebenzi. Lezi zinguquko zingathinta ushukela wegazi lakho nenani le-insulin oyodinga.
• buza udokotela wakho ukuthi kufanele uhlole kaningi kangakanani ushukela wegazi lakho. Yazi ukuthi i-hypoglycemia ingathinta ikhono lakho lokwenza imisebenzi efana nokushayela bese ubuza udokotela wakho ukuthi udinga ukuhlola ushukela wegazi ngaphambi kokushayela noma ukusebenzisa imishini.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Kubalulekile ukudla ukudla okunempilo nokudla cishe inani elifanayo lokudla cishe ngezikhathi ezifanayo usuku ngalunye. Ukweqa noma ukubambezela ukudla noma ukushintsha inani noma uhlobo lokudla okudlayo kungadala izinkinga ngokulawulwa kukashukela egazini lakho.

Ngaphambi kokuba uqale ukusebenzisa i-insulin glargine, cela udokotela wakho ukuthi enzeni uma ukhohlwa ukusebenzisa umthamo noma uma ngephutha usebenzisa umthamo owengeziwe. Bhala lezi zinkomba phansi ukuze ukwazi ukubheka kuzo ngokuhamba kwesikhathi.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-insulin glargine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ububomvu, ukuvuvukala, ubuhlungu, noma ukulunywa endaweni yokujova
• izinguquko ekuzizweleni kwesikhumba sakho, ukuqina kwesikhumba (ukwakha amafutha), noma ukucindezeleka okuncane esikhunjeni (ukonakala kwamafutha)
• umkhuhlane, ukukhwehlela, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka, isifuba, noma ukulunywa emzimbeni wonke
• isifuba
• ukuphefumula kanzima noma ukugwinya
• ishayela ngokushesha
• ukujuluka
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
• ukushaqeka
• ubuthakathaka
• amajaqamba
• ukushaya kwenhliziyo okungavamile
• ukuzuza kwesisindo ngokungazelelwe
• ukuvuvukala kwamaqakala noma izinyawo
• ukuphelelwa umoya
• umbono uyashintsha

I-insulin glargine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Gcina le mithi esitsheni efike ingena futhi ingafinyeleleki ezinganeni. Gcina izimbiza ze-insulin ezingavuliwe nezibaya esiqandisini. Ungalokothi uvumele i-insulin glargine iqhwa; ungasebenzisi i-insulin glargine efriziwe yancibilika. I-insulin glargine engavulwa efrijini ingagcinwa kuze kube usuku oluboniswe kwilebula lenkampani.

Uma isiqandisi singatholakali (ngokwesibonelo, uma useholidini), gcina izitsha noma amapeni ekamelweni lokushisa futhi ungahlali elangeni eliqondile nasekushiseni okukhulu. Izitsha noma izibaya ezingenafriji zingasetshenziswa zingakapheli izinsuku ezingama-28; ngemuva kwalesosikhathi kufanele zilahlwe. Izimbiza ezivuliwe zingagcinwa izinsuku ezingama-28 ekamelweni lokushisa noma esiqandisini. Izibaya ezivuliwe kufanele zigcinwe ekamelweni lokushisa futhi zingasetshenziswa kuze kube yizinsuku ezingama-28 ngemuva kokusetshenziswa kokuqala. Lahla noma iyiphi i-insulini evezwe ukushisa noma amakhaza amakhulu.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

I-insulini glargine overdose ingenzeka uma usebenzisa i-insulin glargine ngokweqile noma uma usebenzisa inani elifanele le-insulin glargine kodwa udle okuncane kunokujwayelekile noma uvivinye umzimba kunokujwayelekile. I-insulin glargine overdose ingadala i-hypoglycemia. Uma unezimpawu ze-hypoglycemia, landela imiyalo kadokotela wakho yokuthi yini okufanele uyenze uma uba ne-hypoglycemia. Ezinye izimpawu zokudlula ngokweqile:

• ukulahlekelwa ukwazi
• isithuthwane

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Ushukela wegazi kanye ne-hemoglobin eglycosylated (HbA1c) kufanele ihlolwe njalo ukuthola impendulo yakho ku-insulin glargine. Udokotela wakho uzokutshela nokuthi ungayihlola kanjani impendulo yakho kulo muthi ngokulinganisa amazinga kashukela egazini lakho ekhaya. Landela le miyalo ngokucophelela.

Kufanele njalo ufake isongo lokuhlonza isifo sikashukela ukuze uqiniseke ukuthi uthola ukwelashwa okufanele esimeni esiphuthumayo.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Basaglar^®
• I-Lantus^®
• Toujeo^®
• Soliqua^® (njengomkhiqizo ohlanganisiwe oqukethe i-Insulin Glargine neLixisenatide),