Isebenza Kanjani Le COVID-19's Vaccine Creator Ukwenza Ukuzinakekela Lapho Engawusindisi Umhlaba

-Delile

• Uhambo Lokwakha Umuthi Wokugoma i-COVID-19
• Indlela Engakuthola Ngayo Ukuzinakekela Phakathi Kwezinxushunxushu
• Ngibheke Phambili
• Buyekeza kwe-

Ngiseyintombazanyana, ngangihlale ngikhangwa izitshalo nezilwane. Nganginelukuluku elijulile lokuthi yini eyenza izinto ziphile, ukwakheka kwazo, kanye nesayensi iyonke engemuva kwayo yonke into esizungezile.

Nokho, emuva ngaleso sikhathi, kwakubhekwa njengento engavamile ukuba amantombazane angene kulezo zinhlobo zezinto. Eqinisweni, kwakunezikhathi lapho ngangiwukuphela kwentombazane emakilasini ami esayensi esikoleni esiphakeme. Othisha nabanye abafundi babevame ukubuza ukuthi ngiyabuza yini ngempela Ngangifuna ukufunda lezi zifundo. Kodwa lawo mazwi awazange angifake esigabeni. Uma kukhona, bangikhuthaza ukuthi ngiqhubeke ngenza engikuthandayo - futhi ekugcineni ngithole i-Ph.D yami. kuzakhi zofuzo zamangqamuzana. (Okuhlobene: Kungani i-U.S. Ngokudingekile Edinga Odokotela Abesifazane Abamnyama Abengeziwe)

Ngemuva kokuthweswa iziqu, ngathuthela eSan Diego (lapho ngisekhona nanamuhla eminyakeni engama-20 kamuva) ukuqedela izifundo zami zobudokotela e-University of California. Ngemva kokuqeda izifundo zami zobudokotela, ngaqala ukugxila ekuthuthukisweni komgomo, ekugcineni ngamukela isikhundla e-INOVIO Pharmaceuticals njengososayensi wezinga lokungena. Iya phambili ngokushesha iminyaka engu-14, futhi manje ngiyisekela likamongameli eliphezulu kwezocwaningo nentuthuko enkampanini.

Phakathi naso sonke isikhathi sami ngise-INOVIO, ngithuthukise futhi ngathuthukisa ukulethwa kwezinhlobonhlobo zemigomo, ikakhulukazi izifo ezithathelwanayo ezisafufusa ezibulalayo njenge-Ebola, iZika, ne-HIV. Mina nethimba lami saba ngabokuqala ukuletha umuthi wokugomela i-Lassa fever (isifo esithwalwa yizilwane, esengozini yokubeka impilo engcupheni esikhona ezingxenyeni ezithile zeNtshonalanga Afrika) emtholampilo, futhi sisizile ukuqhubekisela phambili ukuthuthukiswa komuthi wokugoma I-MERS-CoV, uhlobo lwe-coronavirus olubangela i-Middle East Respiratory Syndrome (MERS), eyathelela abantu ababalelwa ku-2,500 futhi yabulala abanye abacishe babe ngama-900 ngo-2012.

Bengilokhu ngihehwa yindlela la magciwane akwazi ngayo ukusidlula. Iso lenyama alikwazi ngisho nokuzibona, kepha ziyakwazi ukudala ukubhujiswa nobuhlungu obungaka. Kimina, ukuqeda lezi zifo kuyinselelo enkulu futhi enomvuzo omkhulu. Kungumnikelo wami omncane ekuqedeni ukuhlupheka kwabantu.

Ukuqeda lezi zifo kuyinselelo enkulu nezuzisa kakhulu. Kungumnikelo wami omncane ekuqedeni ukuhlupheka kwabantu.

UKate Broderick, ph.d.

Lezi zifo zinomthelela omubi kangaka emiphakathini - eminingi yayo etholakala ezingxenyeni ezisathuthuka zomhlaba. Kusukela ngiqala ukuba usosayensi, Umgomo wami bekuwukuqeda lezi zifo, ikakhulukazi lezo ezihlasela abantu ngendlela engafani.

Uhambo Lokwakha Umuthi Wokugoma i-COVID-19

Ngizohlala ngikhumbula ngimi ekhishini lami ngoDisemba 31, 2019, ngiphuza inkomishi yetiye, lapho ngiqala ukuzwa nge-COVID-19. Ngokushesha, ngangazi ukuthi yinto iqembu lami e-INOVIO elingasiza ekubhekaneni ne-ASAP.

Ngaphambilini, sasike sasebenza ekwakheni umshini ongafaka ukulandelana kofuzo lwanoma yiliphi igciwane futhi udale umklamo walo wokugoma. Lapho sesithole imininingwane yezofuzo mayelana negciwane ebesilidinga eziphathimandleni, singakhiqiza umuthi wokugoma othuthukiswe ngokuphelele (okuyisisekelo sombono womuthi wokugoma) walelo gciwane esikhathini esingaphansi kwamahora amathathu.

Imithi eminingi yokugoma isebenza ngokujova uhlobo olubuthakathaka lwegciwane noma amagciwane emzimbeni wakho. Lokhu kuthatha isikhathi - iminyaka, ezimweni eziningi. Kepha imithi yokugoma esekwe ku-DNA efana neyethu isebenzisa ingxenye yekhodi yezakhi zofuzo ukusiza ukukhuthaza ukuphendula komzimba. (Ngakho-ke, inqubo yokudala eshesha ngokungavamile.)

Yiqiniso, kwezinye izimo, kungathatha ngisho Okuningi isikhathi sokudiliza ukulandelana kofuzo. Kepha nge-COVID, abacwaningi baseShayina bakwazile ukukhulula idatha yokulandelana kofuzo ngesikhathi sokuqopha, okusho ukuthi iqembu lami - nabanye emhlabeni jikelele - lingaqala ukudala abazogomela ngokushesha okukhulu.

Kimina nethimba lami, lo mzuzu ubuyingqophamlando yegazi, umjuluko, izinyembezi, neminyaka esiyibeke ekwakheni ubuchwepheshe obungasisiza silwe negciwane elinjenge-COVID.

Ngaphansi kwezimo ezijwayelekile, isinyathelo esilandelayo kuzoba ukufaka umuthi wokugoma ohlelweni lokugunyaza okulandelanayo - inqubo ngokuvamile edinga isikhathi (ngokuvamile iminyaka) ebesingenaso. Uma sizokuhoxisa lokhu, kuzofanele sisebenze ngokungakhathali. Futhi yilokho kanye esikwenzile.

Kwakuyinqubo ekhandlayo. Mina nethimba lami sichithe amahora angaphezu kwangu-17 ngosuku ebhodini sizama ukufaka umgomo wethu esigabeni sesivivinyo somtholampilo. Uma sithatha ikhefu, kwakuwukulala nokudla. Ukusho ukuthi sikhathele kungukubukela phansi, kepha besazi ukuthi ukuphazamiseka kungokwesikhashana nokuthi inhloso yethu ibinkulu kakhulu kunathi. Yilokho okusenze saqhubeka.

Lokhu kwaqhubeka izinsuku ezingama-83, ngemuva kwalokho umshini wethu wakha ukwakhiwa komuthi wokugoma futhi sawusebenzisa ukwelapha isiguli sethu sokuqala, okwaba yimpumelelo enkulu.

Kuze kube manje, umuthi wethu wokugoma usuqede Isigaba I sokuhlolwa komtholampilo futhi njengamanje useSigabeni sesi-2 sokuhlolwa. Siyethemba ukuthi sizongena ku-Phase 3 ngesinye isikhathi kulo nyaka. Yilapho-ke esizothola khona ukuthi umjovo wethu wokuvikela umuthi uvikela i-COVID nokuthi kungakanani. (Okuhlobene: Konke Odinga Ukukwazi Mayelana Nemiphumela emibi ye-COVID-19 Vaccine Side)

Indlela Engakuthola Ngayo Ukuzinakekela Phakathi Kwezinxushunxushu

Yize kungakanani okusepuletini lami nganoma yisiphi isikhathi (ngingumama wababili ngaphezu kokuba ngusosayensi!), Ngikwenza iphuzu ukudweba isikhathi esithile ukuze nginakekele impilo yami engokwenyama nengokwengqondo. Njengoba i-INOVIO isebenza nabantu abavela kuwo wonke umhlaba, usuku lwami luvame ukuqala ekuseni kakhulu - ngo-4 ekuseni, ukuze kube ngqo. Ngemuva kokusebenza amahora ambalwa, ngichitha imizuzu engama-20 kuye kwengama-30 ngenza i-Yoga no-Adriene ukusiza ukuzinza nokuzikhathaza ngaphambi kokuba ngivuse izingane bese kuqala i-mayhem. (Okuhlobene: Imiphumela Engaba Khona Yezempilo Yengqondo ye-COVID-19 Odinga Ukwazi Ngayo)

Njengoba sengikhulile, ngiye ngabona ukuthi uma ungazinakekeli, ukugcina isimiso esimatasa njengesami akusimeme. Ngaphezu kwe-yoga, kulo nyaka ngihlakulele uthando lwangaphandle, ngakho-ke ngivame ukuhamba amabanga amade nezinja zami ezimbili zokuhlenga. Kwesinye isikhathi ngike ngicindezele naseseshini ebhayisikilini lami lokuzivocavoca ukuze ngithole i-cardio ene-low-intensity. (Okuhlobene: Izinzuzo Zengqondo Nezomzimba Zokusebenza Kwangaphandle)

Ekhaya, mina nomyeni wami sizama ukupheka yonke into kusuka ekuqaleni. Singabantu abadla imifino kuphela, ngakho-ke sizama ukubeka ukudla okunothile okunomsoco emizimbeni yethu nsuku zonke. (Okuhlobene: Izifundo Ezimangalisa Kakhulu Engizifunde Ekuhambeni Kwabadli Bemifino Inyanga)

Ngibheke Phambili

Yize bekuyinselelo kulo nyaka odlule, nawo ube nomvuzo ngendlela emangalisayo. Ngayo yonke imisebenzi esesiyenzile selokhu kwaqala ubhadane, angikwazi ukukutshela ukuthi zingaki izikhathi lapho abantu babelane khona ukuthi kukhuthaza kanjani ukubona owesifazane ehola umzamo onjengalona. Ngizizwe ngihloniphekile futhi ngiziqhenya ngokuthi ngiyakwazi ukuthonya abantu ukuthi balandele indlela yesayensi - ikakhulukazi abesifazane nabantu abavela ezizindeni ezihlukene. (Okuhlobene: Lo Microbiologist Wavusa Umnyakazo Wokubona Ososayensi Abamnyama Ensimini Yakhe)

Ngeshwa, i-STEM iseyindlela ebuswa ngabesilisa. Ngisho nango-2021, ngamaphesenti angama-27 kuphela ochwepheshe be-STEM abangabesifazane. Ngicabanga ukuthi siqonde ohlangothini olufanele, kepha inqubekela phambili ihamba kancane. Ngiyethemba ukuthi ngesikhathi indodakazi yami iya ekolishi, uma ikhetha le ndlela, kuzoba nokumelwa okuqinile kwabesifazane ku-STEM. Singabakule ndawo.

Kubo bonke abasebenzi bezempilo, abasebenza phambili, nabazali, nazi izeluleko zami zokuzinakekela: Ngeke ukwazi ukwenza okudingayo ngokusemandleni akho ngaphandle kokuthi uzinakekele. Njengabesifazane, imvamisa sibeka konke nawo wonke umuntu ngaphambi kwethu, okungaba okutusekayo, kepha kuza thina.

Njengabesifazane, imvamisa sibeka konke nawo wonke umuntu ngaphambi kwethu, okungaba okutusekayo, kepha kuza thina.

Kate Broderick, Ph.d.

Yiqiniso, ukuzinakekela kubonakala kuhlukile kuwo wonke umuntu. Kodwa ukuthatha leyo mizuzu engama-30 yokuthula nsuku zonke ukuze ugcine impilo yakho yengqondo isesimweni - kungaba yindlela yokuzivocavoca, isikhathi sangaphandle, ukuzindla, noma ukugeza okude okushisayo - kubaluleke kakhulu empumelelweni.

Buyekeza kwe-