I-Mycophenolate

-Delile

• Ngaphambi kokuthatha i-mycophenolate,
• I-Mycophenolate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ubungozi bokukhubazeka kokuzalwa:

I-Mycophenolate akufanele ithathwe ngabesifazane abakhulelwe noma abangakhulelwa. Kunobungozi obukhulu bokuthi i-mycophenolate izodala ukuphuphuma kwesisu (ukulahleka kokukhulelwa) ezinyangeni ezintathu zokuqala zokukhulelwa noma kuzobangela ukuthi ingane izalwe inokukhubazeka kokuzalwa (izinkinga ezikhona ngesikhathi sokuzalwa).

Akufanele uthathe i-mycophenolate uma ukhulelwe noma ungakhulelwa. Kufanele ube nokuhlolwa kokukhulelwa okungekuhle ngaphambi kokuqala ukwelashwa kwakho nge-mycophenolate, futhi ngemuva kwezinsuku eziyi-8 kuya kwezingu-10, nasezikhundleni ezijwayelekile zokulandelela. Kufanele usebenzise ukulawulwa kokubeletha okwamukelekayo ngenkathi welashwa, futhi amasonto ayisithupha ngemuva kokuyeka ukuthatha i-mycophenolate. Udokotela wakho uzokutshela ukuthi yiziphi izindlela zokulawula ukubeletha ezamukelekayo ongazisebenzisa. I-Mycophenolate inganciphisa ukusebenza kwezindlela zokuvimbela inzalo ngomlomo (amaphilisi okuvimbela inzalo), ngakho-ke kubaluleke kakhulu ukusebenzisa indlela yesibili yokulawula ukuzalwa kanye nalolu hlobo lokuvimbela inzalo.

Uma ungowesilisa onomlingani wesifazane ongakhulelwa, kufanele usebenzise ukulawulwa kokubeletha okwamukelekayo ngenkathi welashwa futhi okungenani izinsuku ezingama-90 ngemuva komthamo wakho wokugcina. Unganikeli isidoda ngesikhathi sokwelashwa kwakho futhi okungenani izinsuku ezingama-90 ngemuva komthamo wakho wokugcina.

Shayela udokotela wakho ngokushesha uma ucabanga ukuthi wena noma umlingani wakho, ukhulelwe noma uphuthelwa ukuya esikhathini.

Ngenxa yokuthi kungenzeka ukuthi umnikelo wakho ungaya kowesifazane ongakhulelwa noma okhulelwe, unganikeli ngegazi ngesikhathi sokwelashwa kwakho futhi okungenani amasonto ayisithupha ngemuva komthamo wakho wokugcina.

Izingozi zezifo ezimbi:

I-Mycophenolate yenza buthakathaka amasosha omzimba futhi inganciphisa ikhono lakho lokulwa nokutheleleka. Geza izandla zakho njalo uvikele abantu abagulayo ngenkathi uthatha lo muthi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukubanda, noma ukukhwehlela; ukulimaza noma ukopha okungavamile; ubuhlungu noma ukushisa ngesikhathi sokuchama; ukuchama njalo; isilonda noma isilonda esibomvu, esifudumele, noma esingapholi; amanzi avela enxebeni lesikhumba; ubuthakathaka jikelele, ukukhathala ngokweqile, noma ukugula; izimpawu '' zomkhuhlane '' noma '' amakhaza ''; ubuhlungu noma ukuvuvukala entanyeni, emgodini, noma emakhwapheni; amabala amhlophe emlonyeni noma emphinjeni; izilonda ezibandayo; amabhamuza; ikhanda noma ubuhlungu bendlebe; noma ezinye izimpawu zokutheleleka.

Ungahle utheleleke ngamagciwane noma amabhaktheriya athile kepha ungabi nazimpawu zokutheleleka. Ukuthatha i-mycophenolate kwandisa ubungozi bokuthi lezi zifo zizokuba nzima kakhulu futhi zidale izimpawu. Tshela udokotela wakho uma unanoma yiluphi uhlobo lokutheleleka, njenge-Hepatitis B noma C, kufaka phakathi ukutheleleka okungabangeli izimpawu.

I-Mycophenolate ingakhuphula ubungozi bokuthi uzoba ne-leukoencephalopathy eqhubekayo (i-PML), ukutheleleka okungajwayelekile kobuchopho okungenakulashwa, ukuvinjelwa, noma ukwelashwa okuvame ukubangela ukufa noma ukukhubazeka okukhulu). Tshela udokotela wakho uma uke waba ne-PML noma wake waba nesinye isimo esithinta amasosha akho omzimba njengegciwane lesandulela ngculazi (i-HIV); wathola i-immunodeficiency syndrome (i-AIDS); i-sarcoidosis (isimo esidala ukuvuvukala emaphashini futhi kwesinye isikhathi kwezinye izingxenye zomzimba); i-leukemia (umdlavuza obangela ukuthi kukhiqizwe amangqamuzana amaningi egazi futhi adedelwe angene egazini); noma i-lymphoma. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuthakathaka ohlangothini olulodwa lomzimba noma emilenzeni; ubunzima noma ukwehluleka ukulawula imisipha yakho; ukudideka noma ubunzima bokucabanga kahle; ukungazinzi; ukulahleka kwememori; kunzima ukukhuluma noma ukuqonda okushiwo abanye; noma ukungabi nentshisekelo noma ukukhathazeka ngemisebenzi ejwayelekile noma izinto ojwayele ukuzikhathalela.

I-Mycophenolate ingakhuphula ingozi yokuba nezinhlobo ezithile zomdlavuza, kufaka phakathi i-lymphoma (uhlobo lomdlavuza olukhula ohlelweni lwe-lymph) nomdlavuza wesikhumba. Tshela udokotela wakho uma wena noma omunye emndenini wakho unomdlavuza wesikhumba noma owake waba nawo. Gwema ukuchayeka ngokungadingekile noma isikhathi eside elangeni langempela nelokufakelwa (imibhede yokushuka, izibani zelanga) kanye nokwelashwa okulula futhi ugqoke izingubo zokuzivikela, izibuko zelanga, kanye nesikrini (eline-SPF factor engu-30 noma ngaphezulu). Lokhu kuzosiza ukunciphisa ingozi yokuba nomdlavuza wesikhumba. Shayela udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo: ubuhlungu noma ukuvuvukala entanyeni, emgodini, noma emakhwapheni; isilonda esisha noma iqhubu; ushintsho kusayizi noma kumbala wemvukuzane; isilonda esinsundu noma esimnyama sesikhumba (esibuhlungu) esinemiphetho engalingani noma ingxenye eyodwa yesilonda engafani nenye; izinguquko zesikhumba; izilonda ezingapholi; umkhuhlane ongachazeki; ukukhathala okungapheli; noma ukunciphisa umzimba.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-mycophenolate futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) http://www.fda.gov/Drugs ukuthola uMhlahlandlela Wezokwelapha.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-mycophenolate.

Khuluma nodokotela wakho ngezingozi zokuthatha i-mycophenolate.

I-Mycophenolate (CellCept) isetshenziswa neminye imithi yokusiza ukuvimbela ukwenqatshwa kwesitho somzimba (ukuhlaselwa kwesitho esifakelwe amasosha omzimba womuntu othola isitho) kubantu abadala abathole ukufakelwa kwenhliziyo nesibindi nakubantu abadala nezingane izinyanga ezintathu ubudala nangaphezulu abathole ukufakelwa izinso. I-Mycophenolate (Myfortic) isetshenziswa neminye imithi yokusiza ukuvimbela umzimba ekwenqabeni ukufakelwa izinso. IMycophenolate isekilasini lemithi ebizwa ngama-immunosuppressive agents. Isebenza ngokwenza buthakathaka amasosha omzimba ngakho ngeke ihlasele futhi yenqabe isitho esitshalwe kabusha.

I-Mycophenolate iza njenge-capsule, ithebhulethi, ukukhishwa okulibazisekile (kukhipha umuthi emathunjini), kanye nokumiswa (uketshezi) ukuthatha ngomlomo. Imvamisa kuthathwa kabili ngosuku esiswini esingenalutho (ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla noma ukuphuza, ngaphandle kokuthi udokotela wakho akutshele ngenye indlela). Thatha i-mycophenolate cishe ngezikhathi ezifanayo nsuku zonke, bese uzama ukubeka imithamo yakho cishe amahora angama-12 ahlukene. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-mycophenolate njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Imithi ekwithebhulethi ekhishwe ukubambezeleka (i-Myfortic) imuncwa ngokuhlukile ngumzimba kunemithi ekulengiswa, ithebhulethi kanye ne-capsule (CellCept). Le mikhiqizo ayikwazi ukufakwa esikhundleni somunye nomunye. Ngaso sonke isikhathi uma ugcwaliswa ngudokotela, qiniseka ukuthi uwutholile umkhiqizo ofanele. Uma ucabanga ukuthi uthole umuthi ongafanele, khuluma nodokotela wakho nosokhemisi ngokushesha.

Gwinya amathebulethi, amaphilisi akhiphe ukubambezeleka, namaphilisi aphelele; ungawahlukanisi, ungawahlafune noma uwagxoze. Musa ukuvula amaphilisi.

Ungahlanganisi ukumiswa kwe-mycophenolate neminye imithi.

Qaphela ukuthi ungachithi ukumiswa noma ukukusakaza esikhunjeni sakho. Uma uthola ukumiswa esikhunjeni sakho, geza indawo kahle ngensipho namanzi. Uma uthola ukumiswa emehlweni akho, hlambulula ngamanzi alula. Sebenzisa amathawula wephepha emanzi ukusula noma yikuphi uketshezi oluchithekile.

I-Mycophenolate isiza ukuvimbela ukwenqatshwa kokufakelwa komzimba uma nje uthatha umuthi. Qhubeka uthathe i-mycophenolate noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-mycophenolate ngaphandle kokukhuluma nodokotela wakho.

I-Mycophenolate ibuye isetshenziselwe ukwelapha isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukuncipha komzimba nomkhuhlane). Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-mycophenolate,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-mycophenolate, mycophenolic acid, noma imuphi omunye umuthi, noma iziphi izithako kumkhiqizo we-mycophenolate noma i-mycophenolic acid owuthathayo. Uma uthatha uketshezi lwe-mycophenolate, tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-aspartame noma i-sorbitol. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amalahle acushiwe; i-acyclovir (iZovirax); ama-antibiotic athile afana ne-amoxicillin ne-clavulanic acid (Augmentin), i-ciprofloxacin (Cipro) ,, ne-sulfamethoxazole / trimethoprim (Bactrim); i-azathioprine (Azasan, Imuran); cholestyramine (Prevalite); i-ganciclovir (iCytovene, iValcyte); eminye imithi ecindezela amasosha omzimba; isavuconazonium (Cresemba); ama-probenecid (i-Probalan); ama-proton pump inhibitors afana ne-lansoprazole (Dexilant, Prevacid) ne-pantoprazole (Protonix); i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, i-Rifater); telmisartan (Micardis, eTwynsta); i-valacyclovir (iValtrex); kanye ne-valganciclovir (Valcyte). Phinda utshele udokotela wakho uma uthatha inhlanganisela ye-norfloxacin (Noroxin) ne-metronidazole (Flagyl). Eminye imithi eminingi ingase futhi ihlanganyele ne-mycophenolate, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu. Futhi qiniseka ukuthi utshela udokotela wakho uma uyeka ukuthatha noma yimiphi imithi yakho. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha i-sevelamer (Renagel, Renvela), noma ama-antacids aqukethe i-magnesium noma i-aluminium, thatha amahora amabili ngemuva kokuthatha i-mycophenolate.
• Tshela udokotela wakho uma uke waba nesifo i-Lesch-Nyhan syndrome noma i-Kelley-Seegmiller syndrome (izifo ezuzwe njengefa ezibanga amazinga aphezulu ento ethile egazini, ubuhlungu bamalunga, nezinkinga ngokunyakaza nokuziphatha); i-anemia (inani eliphansi kunejwayelekile lamaseli abomvu egazi); i-neutropenia (ngaphansi kwenani elijwayelekile lamaseli amhlophe egazi); izilonda noma yisiphi isifo esithinta isisu sakho, amathumbu, noma uhlelo lokugaya ukudla; noma yiluphi uhlobo lomdlavuza; noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma uncelisa.
• kufanele wazi ukuthi i-mycophenolate ingakwenza ukozele, udideke, unesiyezi, unekhanda elincane, noma kubangele ukuzamazama okungalawuleki kwengxenye yomzimba. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho. Buza udokotela wakho ukuthi kufanele uthole umuthi wokugomela umkhuhlane ngaphambi noma ngesikhathi sokwelashwa kwakho ngoba ukuthatha i-mycophenolate kungandisa ingozi yokutheleleka.
• uma une-phenylketonuria (i-PKU, isimo esizuzwe njengefa lapho kufanele kulandelwe ukudla okhethekile ukuvimbela ukubola kwengqondo), kufanele wazi ukuthi ukumiswa kwe-mycophenolate kuqukethe i-aspartame, umthombo we-phenylalanine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uthatha ithebhulethi ye-mycophenolate, i-capsule, noma ukumiswa (i-Cellcept) thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula. Kodwa-ke, uma umthamo olandelayo ungaphansi kwamahora ama-2, yeqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Uma uthatha ithebhulethi yokukhishwa ye-mycophenolate ebambezelekile (i-Myfortic) thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Mycophenolate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• ubuhlungu besisu noma ukuvuvukala
• isicanucanu
• ukuhlanza
• ubunzima bokulala noma ukulala
• ubuhlungu, ikakhulukazi emuva, imisipha, noma amalunga
• ikhanda
• igesi
• ukubhoboza, ukuhayiza, noma umuzwa ovuthayo esikhumbeni
• ukuqina kwemisipha noma ubuthakathaka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isifo sohudo, ubuhlungu besisu obukhulu ngokuzumayo
• ukuvuvukala kwezandla, izingalo, izinyawo, amaqakala, noma imilenze engezansi
• ukuphefumula kanzima
• ubuhlungu besifuba
• ukuqubuka
• ukulunywa
• ukushaya kwenhliziyo okusheshayo
• isiyezi
• ukuquleka
• ukungabi namandla
• isikhumba esiphaphathekile
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza okunegazi
• hlanza okubukeka njengezizathu zekhofi
• igazi emchameni
• ukuphuzi kwesikhumba noma kwamehlo

I-Mycophenolate ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ukumiswa kwe-Mycophenolate nakho kungagcinwa esiqandisini. Ungafaki ukumiswa kwe-mycophenolate. Lahla noma yikuphi ukumiswa okungasetshenziswanga kwe-mycophenolate ngemuva kwezinsuku ezingama-60.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ubuhlungu besisu
• isicanucanu
• ukuhlanza
• isilungulela
• isifo sohudo
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukukhwehlela nezinye izimpawu zokutheleleka

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• CellCept^®
• I-Myfortic^®