I-Hydroxychloroquine

-Delile

• Ngaphambi kokuthatha i-hydroxychloroquine,
• I-Hydroxychloroquine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Hydroxychloroquine ifundelwe ukwelashwa nokuvimbela isifo se-coronavirus 2019 (COVID-19).

I-FDA ivume Ukugunyazwa Kokusetshenziswa Okuphuthumayo (i-EUA) ngoMashi 28, 2020 ukuvumela ukusatshalaliswa kwe-hydroxychloroquine ukwelapha abantu abadala nentsha enesisindo okungenani samakhilogremu ayi-50 futhi angobani ungeniswe esibhedlela nge-COVID-19, kepha abangakwazi ukubamba iqhaza ocwaningweni lomtholampilo. Kodwa-ke, i-FDA yakukhansela lokhu ngoJuni 15, 2020 ngoba izifundo zokwelashwa zabonisa ukuthi i-hydroxychloroquine ayinakwenzeka ukuthi isebenze ekwelapheni i-COVID-19 kulezi ziguli neminye imiphumela emibi, njengokushaya kwenhliziyo okungajwayelekile, kwabikwa.

I-FDA kanye neNational Institutes of Health (NIH) bathi i-hydroxychloroquine kufanele ithathwe KUPHELA ukuze yelashwe i-COVID-19 ngaphansi kokuqondisa kukadokotela ocwaningweni lomtholampilo. Ungathengi lo muthi online ngaphandle kwemithi kadokotela. Uma uhlangabezana nokushaya kwenhliziyo okungajwayelekile, isiyezi, noma ukuquleka ngenkathi uthatha i-hydroxychloroquine, shayela u-911 ukuthola ukwelashwa okuphuthumayo. Uma uneminye imiphumela emibi, qiniseka ukuthi utshela udokotela wakho.

I-Hydroxychloroquine isetshenziselwa ukuvimbela nokwelapha ukuhlaselwa okunamandla kukamalaleveva. Ibuye isetshenziselwe ukwelapha i-discoid lupus erythematosus (i-DLE; isimo esingalapheki sokuvuvukala kwesikhumba) noma i-systemic lupus erythematosus (i-SLE; isimo esingelapheki sokuvuvukala komzimba) kanye nesifo samathambo kwiziguli ezinezimpawu zazo ezingathuthukile nezinye izindlela zokwelapha. I-Hydroxychloroquine isesigabeni semithi ebizwa ngama-antimalarials. Isebenza ngokubulala izinto ezibanga umalaleveva. I-Hydroxychloroquine ingasebenza ekwelapheni i-rheumatoid arthritis kanye ne-systemic lupus erythematosus ngokunciphisa ukusebenza kwamasosha omzimba.

I-Hydroxychloroquine iza njengethebhulethi yokuphuza ngomlomo. Uma ungumuntu omdala futhi uthatha i-hydroxychloroquine ukuvikela umalaleveva, isilinganiso esisodwa sithathwa kanye ngesonto ngosuku olufanayo lwesonto ngalinye. Uzoqala ukwelashwa amasonto ayi-1 kuya kwayi-2 ngaphambi kokuya endaweni lapho kuvame khona umalaleveva bese uqhubeka ngesikhathi sakho kuleyo ndawo kanye nasemavikini amane ubuyile. Uma ungumuntu omdala futhi uthatha i-hydroxychloroquine ukwelapha umalaleveva, umthamo wokuqala uvame ukuthathwa zisuka nje, ulandelwe ngomunye umthamo amahora ayisithupha kuya kwayisi-8 kamuva bese kuba nemithamo eyengeziwe osukwini ngalunye kulezi ezimbili ezilandelayo. Ngokuvikela noma ukwelashwa kukamalaleveva ezinganeni nasezinganeni, inani le-hydroxychloroquine lincike esisindweni sengane. Udokotela wakho uzobala le mali bese ekutshela ukuthi ingane yakho kufanele ithole malini i-hydroxychloroquine.

Uma uthatha i-hydroxychloroquine ukwelapha i-lupus erythematosus (DLE noma i-SLE), imvamisa iphuzwa kanye noma kabili ngosuku. Uma uthatha i-hydroxychloroquine ukwelapha isifo samathambo, imvamisa iphuzwa kanye noma kabili ngosuku.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Amaphilisi e-Hydroxychloroquine angaphuzwa ngengilazi yobisi noma ngesidlo ukunciphisa isicanucanu.

Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-hydroxychloroquine njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uthatha i-hydroxychloroquine yezimpawu zesifo samathambo, izimpawu zakho kufanele zithuthuke kungakapheli izinyanga eziyisithupha. Uma izimpawu zakho ze-rheumatoid arthritis zingathuthuki, noma uma ziba zimbi kakhulu, yeka ukuthatha lesi sidakamizwa futhi ushayele udokotela wakho. Lapho nje wena nodokotela wakho seninesiqiniseko sokuthi umuthi uyakusebenzela, ungayeki ukuthatha i-hydroxychloroquine ngaphandle kokukhuluma nodokotela wakho. Izimpawu zesifo samathambo zizobuya uma uyeka ukuthatha i-hydroxychloroquine.

I-Hydroxychloroquine isetshenziswa ngezikhathi ezithile ukwelapha i-porphyria cutanea tarda. Khuluma nodokotela wakho ngezingozi ezingenzeka zokusebenzisa lesi sidakamizwa ngesimo sakho.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-hydroxychloroquine,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-hydroxychloroquine, i-chloroquine, i-primaquine, i-quinine, noma enye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho i-acetaminophen (iTylenol, abanye); i-azithromycin (iZithromax); i-cimetidine (Tagamet); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-digoxin (i-Lanoxin), i-insulin nemithi yomlomo yesifo sikashukela; imishanguzo yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), noma i-valproic acid (Depakene); imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Pacerone); i-methotrexate (Trexall, Xatmep); moxifloxacin (Avelox); i-praziquantel (i-Biltricide); kanye ne-tamoxifen (Nolvadex). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-hydroxychloroquine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• uma uthatha ama-antacids, thatha amahora amane ngaphambi noma ngemuva kwamahora amane ngemuva kwe-hydroxychloroquine. Uma uthatha i-ampicillin, yithathe okungenani amahora ama-2 ngaphambi noma amahora amabili ngemuva kwe-hydroxychloroquine.
• Tshela udokotela wakho uma uke waba nesifo sesibindi, isifo senhliziyo, isikhawu se-QT eside (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe), ukushaya kwenhliziyo okungajwayelekile, izinga eliphansi le-magnesium noma i-potassium ku igazi lakho, i-psoriasis, i-porphyria noma okunye ukuphazamiseka kwegazi, ukushoda kwe-G-6-PD (isifo segazi esizuzwe njengefa), i-dermatitis (ukuvuvukala kwesikhumba), ukuquleka, izinkinga zokubona, isifo sikashukela, izinkinga zezinso, noma uma uphuza utshwala obuningi.
• Tshela udokotela wakho uma ngabe uke waba nezinguquko zombono ngenkathi uthatha i-hydroxychloroquine, i-chloroquine (Aralen), noma i-primaquine.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-hydroxychloroquine, shayela udokotela wakho.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Hydroxychloroquine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isiyezi
• ukulahlekelwa isifiso sokudla
• isicanucanu
• isifo sohudo
• ubuhlungu besisu
• ukuhlanza
• ukuqubuka

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

• ubunzima bokufunda noma ukubona (amagama, izinhlamvu, noma izingxenye zezinto ezingekho)
• ukuzwela ekukhanyeni
• ukungaboni kahle
• izinguquko embonweni
• ukubona ukukhanya okukhanyayo noma izintambo
• kunzima ukuzwa
• kukhala ezindlebeni
• ubuthakathaka bemisipha
• ukopha okungajwayelekile noma ukulinyazwa
• amakhandlela noma ukulahleka kwezinwele
• ukushintsha kwemizwelo noma kwengqondo
• ukushaya kwenhliziyo okungajwayelekile
• ukozela
• ukudlikizela
• kwehle ukwazi noma ukulahlekelwa ukwazi
• ucabanga ngokuzilimaza noma ukuzibulala

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ikhanda
• ukozela
• ukuphazamiseka okubukwayo
• ukudlikizela
• ukushaya kwenhliziyo okungajwayelekile

Izingane zingazwela kakhulu ekweqeni ngokweqile, ngakho-ke gcina umuthi lapho izingane zingafinyeleli kuwo. Izingane akufanele zithathe i-hydroxychloroquine ukwelashwa kwesikhathi eside.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda ezinye izivivinyo zelebhu kanye nama-electrocardiograms (EKG, isivivinyo sokuqapha izinga lokushaya kwenhliziyo yakho nesigqi) ukuhlola impendulo yakho ku-hydroxychloroquine.

Uma uthatha i-hydroxychloroquine isikhathi eside, udokotela wakho uzoncoma izivivinyo zamehlo njalo. Kubaluleke kakhulu ukuthi ugcine lezi zikhundla. I-Hydroxychloroquine ingadala izinkinga ezinkulu zokubona. Uma uhlangabezana nanoma yiziphi izinguquko embonweni, yeka ukuthatha i-hydroxychloroquine bese ushayela udokotela wakho ngokushesha.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Plaquenil^®