Ukulungiswa kabusha

-Delile

• I-Risedronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu exhuma umlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwa ngokwemiyalelo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:
• Ngaphambi kokuthatha i-risedronate,
• I-Risedronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yimiphi imiphumela emibi elandelayo, shayela udokotela wakho ngokushesha ngaphambi kokuthi uthathe noma iyiphi i-risedronate:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Amaphilisi e-Risedronate kanye nokubambezeleka kokukhishwa (amaphilisi asebenza isikhathi eside) asetshenziselwa ukuvimbela nokwelapha i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi aphuke kalula) kwabesifazane abathole ukuya esikhathini ('' ushintsho lwempilo, '' ukuphela wezikhathi zokuya esikhathini). Amaphilisi e-Risedronate asetshenziselwa ukwelapha i-osteoporosis emadodeni, nakwabesilisa nabesifazane abathatha i-glucocorticoids (uhlobo lwemithi ye-corticosteroid engadala i-osteoporosis). Amaphilisi e-Risedronate nawo asetshenziselwa ukwelapha isifo sePaget samathambo (isimo lapho amathambo ethambile futhi ebuthakathaka futhi engahle akhubazeke, abuhlungu, noma aphuke kalula). I-Risedronate isekilasini lemithi ebizwa ngama-bisphosphonates. Isebenza ngokuvimbela ukuwohloka kwamathambo nokwandisa ukuminyana kwethambo (ukujiya).

I-Risedronate iza njengethebhulethi kanye nethebhulethi ekhishwe ukubambezeleka ezothathwa ngomlomo. Amaphilisi okukhululwa abambezelekile ngokuvamile athathwa kanye ngesonto ekuseni, ngokushesha nje emva kokudla kwasekuseni. Amaphilisi ngokuvamile athathwa esiswini esingenalutho kanye ngosuku ekuseni, kanye ngesonto ekuseni, kanye ngenyanga njalo ngenyanga, noma kanye ngenyanga njalo ekuseni kabili zilandelana kuye ngesimo sakho nomthamo obekwe udokotela wakho. Uma uthatha i-risedronate kanye ngesonto, kanye ngenyanga, noma kanye ngenyanga ngezinsuku ezi-2 zilandelana, yithathe ngosuku olufanayo njalo ngesonto noma ngenyanga noma izinsuku ezi-2 zilandelana njalo ngenyanga. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-risedronate njengoba nje uqondisiwe. Ungayithathi ngaphezulu noma ngaphansi kwayo noma uyithathe kaningi noma isikhathi eside kunokuyalelwa ngudokotela wakho.

I-Risedronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu exhuma umlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwa ngokwemiyalelo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:

• Kufanele uphuze amaphilisi e-risedronate ngokushesha nje lapho uvuka embhedeni ekuseni nangaphambi kokuba udle noma uphuze noma yini. Kufanele uphuze amaphilisi okwehlisa okwesikhashana e-risedronate ngokushesha ngemuva kokudla kwasekuseni. Ungalokothi uthathe i-risedronate ngesikhathi sokulala noma ngaphambi kokuba uvuke futhi uvuke embhedeni wosuku.
• Gwinya amathebulethi ngengilazi egcwele (amamitha ayi-180 kuye kwayi-240) wamanzi angenalutho ngenkathi uhleli noma umile. Gwinya amathebulethi akhiphe ukubambezeleka okungenani ngama-ounces ama-4 (120 ml) wamanzi angenalutho ngenkathi uhleli noma umile. Ungalokothi uthathe i-risedronate netiye, ikhofi, ujusi, amanzi amaminerali, ubisi, ezinye iziphuzo zobisi, noma yiluphi uketshezi ngaphandle kwamanzi angenalutho.
• Gwinya amathebulethi namaphilisi okukhipha okulibazisekile ephelele. Musa ukuhlukanisa, ukuhlafuna, noma ukuchoboza. Ungamunci amaphilisi noma uwabambe emlonyeni wakho nganoma isiphi isikhathi.
• Ngemuva kokuthatha i-risedronate, ungadli, ungaphuzi, noma uthathe noma imiphi eminye imithi okungenani imizuzu engama-30. Musa ukulala phansi okungenani imizuzu engama-30 ngemuva kokuthatha i-risedronate. Hlala ume uqonde noma ume mpo kuze kudlule okungenani imizuzu engama-30.

I-Risedronate ilawula i-osteoporosis kanye nesifo sePaget samathambo kodwa ayizelaphi lezi zimo. I-Risedronate iyasiza ekwelapheni nasekuvimbeleni ukukhumuzeka kwamathambo kuphela uma nje ithathwa njalo. Qhubeka uthathe i-risedronate noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-risedronate ngaphandle kokukhuluma nodokotela wakho, kodwa khuluma nodokotela wakho ngezikhathi ezithile mayelana nokuthi usadinga ukuthatha i-risedronate.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-risedronate futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-risedronate,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-risedronate, noma imuphi omunye umuthi, noma iziphi izithako ezisemaphilisi e-risedronate noma amaphilisi okukhipha okulibazisekile. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: i-angiogenesis inhibitors efana ne-bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), noma sunitinib (Sutent); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Ibu-Tab, Motrin, abanye) kanye ne-naproxen (Aleve, Naprelan, Naprosyn, abanye); i-chemotherapy yomdlavuza; noma i-oral steroids efana ne-dexamethasone, methylprednisolone (Medrol), ne-prednisone (i-Rayos). Uma uphuza amaphilisi okukhipha okulibazisekile, kufanele futhi utshele udokotela wakho uma uthatha i-H₂ i-blocker efana ne-cimetidine, i-famotidine (i-Pepcid), i-nizatidine (i-Axid), ne-ranitidine (i-Zantac) noma i-proton pump inhibitor efana ne-esomeprazole (Nexium, eVimovo), i-lansoprazole (i-Prevacid), i-omeprazole (i-Prilosec, i-Zegerid), i-pantopraz ), kanye ne-rabeprazole (AcipHex). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• kufanele wazi ukuthi u-Actonel no-Atelvia bobabili baqukethe i-risedronate. Awukwazi ukuthatha yomibili le mithi ngasikhathi sinye.
• uma uthatha noma imiphi eminye imishanguzo yomlomo efaka amavithamini, izithasiselo, noma ama-antacids, thatha okungenani imizuzu engama-30 ngemuva kokuthatha i-risedronate.
• utshele udokotela wakho ukuthi uke waba nezinga eliphansi le-calcium egazini lakho noma yiziphi izinkinga nge-esophagus yakho futhi uma ungakwazi ukuhlala uqonde noma ume uqonde okungenani imizuzu engama-30. Udokotela wakho angakutshela ukuthi akufanele uthathe i-risedronate.
• tshela udokotela wakho uma uthola ukwelashwa ngemisebe; uma uke waba nenkinga yokugwinya noma owake wakuthola; isilungulela; izilonda noma ezinye izinkinga ngesisu sakho; i-anemia (isimo lapho amangqamuzana abomvu egazi engalethi umoya-mpilo owenele kuzo zonke izingxenye zomzimba); umdlavuza; noma yiluphi uhlobo lokutheleleka, ikakhulukazi emlonyeni wakho; izinkinga ngomlomo wakho, ngamazinyo, noma ngezinsini; noma isiphi isimo esivimba igazi lakho ekunqandeni ngokujwayelekile; noma isifo samazinyo noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uncelisa. Phinda utshele udokotela wakho uma uhlela ukukhulelwa nganoma yisiphi isikhathi ngokuzayo, ngoba i-risedronate ingahlala emzimbeni wakho iminyaka ngemuva kokuyeka ukuyithatha. Shayela udokotela wakho uma ukhulelwa ngesikhathi noma ngemuva kokwelashwa kwakho nge-risedronate.
• kufanele wazi ukuthi i-risedronate ingadala ubuhlungu obukhulu bethambo, imisipha, noma amalunga. Ungaqala ukuzwa lobu buhlungu kungakapheli izinsuku, izinyanga, noma iminyaka ngemuva kokuqala ukuthatha i-risedronate. Yize lolu hlobo lobuhlungu lungaqala ngemuva kokuthi uthathe i-risedronate isikhathi esithile, kubalulekile ukuthi wena nodokotela wakho nazi ukuthi kungabangelwa yi-risedronate. Shayela udokotela wakho ngokushesha uma uzwa ubuhlungu obukhulu nganoma yisiphi isikhathi ngesikhathi sokwelashwa kwakho nge-risedronate. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-risedronate futhi ubuhlungu bakho bungaphela ngemuva kokuyeka ukuthatha umuthi.
• kufanele wazi ukuthi i-risedronate ingadala i-osteonecrosis yomhlathi (i-ONJ, isimo esibi sethambo lomhlathi), ikakhulukazi uma uhlinzwa noma ukwelashwa ngenkathi uthatha umuthi. Udokotela wamazinyo kufanele ahlole amazinyo akho futhi enze noma yiziphi izindlela zokwelashwa ezidingekayo, kufaka phakathi ukuhlanza noma ukulungisa amazinyo okufakelwa angalungile, ngaphambi kokuba uqale ukuthatha i-risedronate. Qiniseka ukuthi uxubha amazinyo futhi uhlanza umlomo wakho kahle ngenkathi uthatha i-risedronate. Khuluma nodokotela wakho ngaphambi kokuthola noma yikuphi ukwelashwa kwamazinyo ngenkathi uthatha lo muthi.
• khuluma nodokotela wakho ngezinye izinto ongazenza ukuvimbela ukukhumuzeka kwamathambo ekukhuleni noma ekukhuleni. Udokotela wakho mhlawumbe uzokutshela ukuthi ugweme ukubhema nokuphuza utshwala obuningi futhi ulandele uhlelo olujwayelekile lokuzivocavoca umzimba.

Kufanele udle ukudla okuningi okunothe nge-calcium nevithamini D ngenkathi uthatha i-risedronate. Udokotela wakho uzokutshela ukuthi yikuphi ukudla okuyimithombo emihle yalezi zinongo nokuthi zingaki izinsizakalo ozidingayo usuku ngalunye. Uma ukuthola kunzima ukudla okwanele kulokhu kudla, tshela udokotela wakho. Uma kunjalo, udokotela wakho angakunikeza noma ancome ukuthi kufakwe isengezo.

Uma uphuthelwa umthamo we-risedronate kanye-nsuku zonke, ungathathi ngokuhamba kosuku. Yeqa umthamo ophuthelwe uthathe umthamo owodwa ekuseni ngakusasa njengenjwayelo.

Uma uphuthelwa umthamo we-risedronate kanye ngesonto, ungayithathi ngokuhamba kosuku. Thatha umthamo owodwa ekuseni ngemuva kokukhumbula. Bese ubuyela ekuthatheni umthamo owodwa kanye ngesonto ngosuku lwakho oluhleliwe njalo.

Uma uphuthelwa umthamo we-risedronate kanye ngenyanga kodwa ukhumbula izinsuku ezingaphezu kwezingu-7 ngaphambi komthamo wakho olandelayo ohleliwe, thatha umthamo ongabanjwanga ekuseni ngemuva kokukhumbula. Uma ukhumbula ngaphansi kwezinsuku eziyi-7 ngaphambi komthamo wakho olandelayo ohleliwe, ungathathi umthamo ongabanjwanga. Esikhundleni salokho, linda kuze kube sekuseni komthamo wakho olandelayo ohleliwe bese uthatha i-risedronate njengokujwayelekile.

Uma uphuthelwa umthamo owodwa noma womabili ezinsukwini ezimbili zilandelana, i-risedronate yanyanga zonke kodwa ukhumbule izinsuku ezingaphezu kwezingu-7 ngaphambi komthamo wakho olandelayo ohleliwe, ungathatha imithamo ephuthelwe. Thatha umthamo wokuqala ongabanjwanga ekuseni ngemuva kokukhumbula futhi uma uphuthelwe yimithamo yomibili, thatha isilinganiso sesibili esilahlekile ekuseni ngemuva kokuthatha owokuqala. Uma ukhumbula ezinsukwini ezingaphansi kwezingu-7 ngaphambi komthamo wakho olandelayo ohleliwe, ungathathi imithamo engaphuthi. Esikhundleni salokho, linda kuze kube sekuseni komthamo wakho olandelayo ohleliwe bese uthatha i-risedronate njengokujwayelekile.

Uma uphuthelwa imithamo ye-risedronate futhi ungazi ukuthi wenzeni, shayela udokotela wakho. Ngaso sonke isikhathi thatha into yokuqala e-risedronate ekuseni. Ungalokothi uthathe umthamo ophindwe kabili ukwenzela okulahlekile, futhi ungalokothi uthathe umthamo ongaphezu kowodwa ngosuku olulodwa.

I-Risedronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukubhoboza
• umlomo owomile
• ubuhlungu besisu
• isifo sohudo
• ukuqunjelwa
• igesi
• ikhanda
• isiyezi
• ubuthakathaka
• amajaqamba omlenze
• ukuhlungu obusemhlane
• kaningi noma ngokuphuthumayo isidingo sokuchama
• ukuchama kabuhlungu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yimiphi imiphumela emibi elandelayo, shayela udokotela wakho ngokushesha ngaphambi kokuthi uthathe noma iyiphi i-risedronate:

• ubunzima bokugwinya noma ubuhlungu lapho ugwinya
• isilungulela esisha noma esiba sibi kakhulu
• ubuhlungu besifuba
• ukulunywa
• ukuqubuka
• isifuba
• amabhamuza esikhunjeni
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuphefumula kanzima
• ukushaqeka
• ukuqina kwemisipha, ukudikiza, noma amajaqamba
• ukuba ndikindiki noma ukuncinza emlonyeni noma ezandleni noma ezinyaweni
• amehlo avuvukile, abomvu, noma abuhlungu
• ukuzwela ekukhanyeni
• izinsini ezibuhlungu noma ezivuvukele
• ukukhululeka kwamazinyo
• ukuba ndikindiki noma ukuzwa okusindayo emhlathini
• ukwelashwa kabi komhlathi
• ubuhlungu obubuhlungu, obuhlungu ezinqulwini, emgodini, noma emathangeni

I-Risedronate ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Ukuthatha imithi ye-bisphosphonate efana ne-risedronate ye-osteoporosis kungakhuphula ubungozi bokuthi uzophula amathambo akho ethanga. Ungabuzwa ubuhlungu okhalweni lwakho, emgodini, noma emathangeni amasonto ambalwa noma izinyanga ngaphambi kokuphuka kwamathambo, futhi ungathola ukuthi elilodwa noma womabili amathambo akho ethanga aphukile yize ungazange uwe noma wehlelwe okunye ukuhlukumezeka.Akujwayelekile ukuthi ithambo lamathanga liphuke kubantu abaphilile, kepha abantu abane-osteoporosis bangalimaza leli thambo noma bengathathi i-risedronate. Khuluma nodokotela wakho ngezingozi zokuthatha i-risedronate.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, nikeza isisulu ingilazi egcwele yobisi bese ushayela isikhungo sendawo sakho sokulawula ubuthi ku-1-800-222-1222. Uma isisulu siwile noma singaphefumuli, shayela abezimo eziphuthumayo zendawo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuba ndikindiki noma ukuncinza emlonyeni noma ezandleni noma ezinyaweni
• ukuphazamiseka kwemisipha, amajaqamba, noma ukugoqana
• isithuthwane

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri noma ithambo lokucabanga ngethambo, tshela udokotela wakho kanye nabasebenzi baselebhu ukuthi uthatha i-risedronate.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Actonel^®
• Atelvia

• Actonel^® ne-Calcium (equkethe i-Calcium, Risedronate)