I-Temozolomide

-Delile

• Ngaphambi kokuthatha i-temozolomide,
• I-Temozolomide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-temozolomide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Temozolomide isetshenziselwa ukwelapha izinhlobo ezithile zezicubu zobuchopho. I-Temozolomide isekilasini lemithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

ITemozolomide iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku kusihlwa ngesikhathi sokulala. Thatha amaphilisi e-temozolomide esiswini esingenalutho ngengilazi yamanzi. Thatha i-temozolomide ngasikhathi sinye nsuku zonke. Kwezinye izinhlobo zamathumba obuchopho, i-temozolomide ithathwa nsuku zonke izinsuku ezingama-42-49. Ngemuva kwalokho, ngemuva kwekhefu lezinsuku ezingama-28, kungathathwa kanye ngosuku izinsuku ezi-5 zilandelana, kulandelwe ikhefu lezinsuku ezingama-23 ngaphambi kokuphinda umjikelezo wesilinganiso olandelayo. Ngokwelashwa kwezinye izinhlobo zamathumba obuchopho, i-temozolomide ithathwa kanye ngosuku izinsuku ezi-5 zilandelana, ilandelwa ikhefu lezinsuku ezingama-23 ngaphambi kokuphinda umjikelezo wesilinganiso olandelayo. Udokotela wakho uzonquma ukuthi kufanele uphinde kangaki imijikelezo yokwelashwa. Isikhathi sokwelashwa sincike ekutheni umzimba wakho usabela kahle kanjani kiso kanye nohlobo lomdlavuza onawo. Thatha i-temozolomide njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Umthamo wakho ogcwele ungaqukatha izinhlobo ezingaphezu kweyodwa nombala wamaphilisi futhi ungaqukethwa ebhodleleni lokudokotela elingaphezu kwelilodwa. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi.

Amaphilisi weTemozolomide angena ngamandla ahlukahlukene ahlukahlukene. Udokotela wakho angafuna ukuthi uthathe inhlanganisela yamaphilisi okwenza umthamo wakho ogcwele. Qiniseka ukuthi uyazi ukuthi uhlobo ngalunye lwe-capsule lubukeka kanjani nokuthi uzothatha kangaki ngalunye. Buza udokotela wakho noma usokhemisi uma unemibuzo.

Uma noma yimaphi ama-capsule ephukile noma evuza, ungawathinti ngezandla zakho futhi uqaphele ukuthi ungaphefumuli impuphu evela kuma-capsules. Kufanele ugqoke amagilavu ​​enjoloba noma e-latex lapho uphatha amaphilisi aphukile noma avuliwe ukuze isikhumba sakho singathintani nampuphu. Uma okuqukethwe kwe-capsule kuthinta isikhumba sakho, geza indawo kahle ngamanzi ngokushesha.

Gwinya wonke amaphilisi; ungazikhiphi, uzihlafune noma uzichoboze.

Ungahlanza ngemuva kokuthatha umuthi. Uma lokhu kwenzeka, yazisa udokotela wakho ngokushesha. Ungathathi omunye umthamo we-temozolomide ngosuku olufanayo.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho we-temozolomide ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi ohlangabezana nayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha i-temozolomide ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-temozolomide,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-temozolomide, i-dacarbazine (i-DTIC-Dome) noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule e-temozolomide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Epitol, Tegretol); co-trimoxazole (Bactrim, Septra); i-phenytoin (iDilantin, Phenytek); i-steroids efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (i-Medrol) ne-prednisone (i-Deltasone); ne-valproic acid (iStavzor, ​​iDepakene).
• tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• kufanele wazi ukuthi i-temozolomide ingaphazamisa ukukhiqizwa kwesidoda emadodeni. Kodwa-ke, akufanele ucabange ukuthi awukwazi ukukhulelisa omunye umuntu. Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthatha i-temozolomide. Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-temozolomide, shayela udokotela wakho. I-Temozolomide ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-temozolomide.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Khuluma nodokotela wakho ngalokho okufanele ukwenze uma uphuthelwa umthamo we-temozolomide. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Temozolomide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• izilonda emlonyeni nasemphinjeni
• ikhanda
• isikhumba esiphaphathekile
• ukungabi namandla
• ukulahlekelwa ibhalansi noma ukuxhumanisa
• ukuquleka
• isiyezi
• ukulahleka kwezinwele
• ukuqwasha
• izinkinga zememori
• izinguquko embonweni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-temozolomide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukopha okungajwayelekile noma ukulinyazwa
• okubomvu noma okumnyama, izitulo zokulinda
• umchamo obomvana, obomvu, noma onsundu
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuqubuka
• ayikwazi ukuhambisa uhlangothi olulodwa lomzimba
• ukuphelelwa umoya
• isithuthwane
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuncipha kokuchama

I-Temozolomide ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-temozolomide.

I-Temozolomide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukopha okungajwayelekile noma ukulinyazwa
• okubomvu noma okumnyama, izitulo zokulinda
• umchamo obomvana, obomvu, noma onsundu
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda ukuhlolwa kwelabhoratri ngaphambi, ngesikhathi, nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-temozolomide nokubheka ukuthi amaseli akho egazi ayathinteka yini kulo muthi.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Temodar^®