Ukujova kwe-Etanercept

-Delile

• Ngaphambi kokusebenzisa umjovo we-etanercept,
• I-Etanercept ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana neminye yale miphumela engemihle elandelayo noma leyo eshiwo ESIGXWAYINI ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole usizo oluphuthumayo lwezokwelapha:

Ukusebenzisa umjovo we-etanercept kunganciphisa ikhono lakho lokulwa nokutheleleka futhi kwandise ubungozi bokuthi uthole ukutheleleka okungathi sína, kufaka phakathi ukutheleleka okunzima ngegciwane, amagciwane noma ukhunta okusakazeka emzimbeni wonke. Lezi zifo zingadinga ukwelashwa esibhedlela futhi zingadala nokufa. Tshela udokotela wakho uma uvame ukuthola noma yiluphi uhlobo lokutheleleka noma uma ucabanga ukuthi ungaba nanoma yiluphi uhlobo lokutheleleka manje. Lokhu kufaka ukutheleleka okuncane (njengokusikeka okuvulekile noma izilonda), izifo ezifika zidlule (njengezilonda ezibandayo) kanye nezifo ezingamahlalakhona ezingapheli. Phinda utshele udokotela wakho uma ngabe uke waba nesifo sikashukela noma unesifo sikashukela, i-human immunodeficiency virus (HIV), uthola i-immunodeficiency syndrome (i-AIDS), noma esinye isimo esithinta amasosha akho omzimba. Kufanele futhi utshele udokotela wakho uma uhlala noma owake wahlala ezindaweni ezinjengezigodi zemifula i-Ohio neMississippi lapho ukutheleleka okunzima kwefungal kuvame kakhulu. Buza udokotela wakho uma ungazi ukuthi ngabe lezi zifo zivamile yini endaweni yangakini. Phinda utshele udokotela wakho uma uphuza imishanguzo eyehlisa ukusebenza kohlelo lomzimba njengokulandelayo: abatacept (Orencia); anakinra (Kineret); i-azathioprine (Imuran); ama-steroids afaka i-dexamethasone, i-methylprednisolone (Medrol), i-prednisolone (i-Prelone) ne-prednisone; noma i-methotrexate (Rheumatrex).

Udokotela wakho uzokuqapha ngezibonakaliso zokutheleleka ngesikhathi nangemva nje kokwelapha kwakho. Uma unezinye zalezi zimpawu ezilandelayo ngaphambi kokuba uqale ukwelashwa kwakho noma uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokwelapha kwakho, shayela udokotela wakho ngokushesha: ubuthakathaka; ukujuluka; ukuphefumula kanzima; Umphimbo obuhlungu; ukukhwehlela; ukukhwehlela amafinyila anegazi; imfiva; ukuncipha komzimba; ukukhathala ngokweqile; isifo sohudo; ubuhlungu besisu; izimpawu ezinjengomkhuhlane; isikhumba esifudumele, esibomvu, noma esibuhlungu; noma ezinye izimpawu zokutheleleka.

Ungahle utheleleke ngesifo sofuba (i-TB, uhlobo lokutheleleka kwamaphaphu) noma i-hepatitis B (uhlobo lwesifo sesibindi) kepha ungenazo izimpawu zesifo. Kulokhu, umjovo we-etanercept ungakhuphula ubungozi bokuthi ukutheleleka kwakho kube kubi kakhulu futhi uzoba nezimpawu. Udokotela wakho uzohlola isikhumba ukuze abone ukuthi unesifo se-TB esingasebenzi yini futhi angahle ahlele ukuhlolwa kwegazi ukubona ukuthi unesifo se-hepatitis B esingasebenzi yini. Uma kunesidingo, udokotela wakho uzokunika umuthi wokwelapha lesi sifo ngaphambi kokuba uqale ukusebenzisa umjovo we-etanercept. Tshela udokotela wakho uma uke waba ne-TB noma wake waba nayo, uma ngabe uhlala ezweni lapho i-TB ijwayelekile khona, noma uma wake waba seduze komuntu one-TB. Uma unezinye zalezi zimpawu ze-TB ezilandelayo, noma uma uba nalezi zimpawu ngesikhathi sokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhwehlela, ukwehla kwesisindo, ukulahleka kwethoni lezicubu, noma umkhuhlane. Phinda ushayele udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu zesifo sokusha kwesibindi kohlobo B noma uma uba nanoma yiziphi zalezi zimpawu ngesikhathi noma ngemuva kokwelashwa kwakho: ukukhathala ngokweqile, ukuphuzi kwesikhumba noma kwamehlo, ukulahlekelwa isifiso sokudla, isicanucanu noma ukuhlanza, izinhlungu zemisipha, umchamo omnyama, ukuhamba kwamathumbu anombala wobumba, umkhuhlane, amakhaza, ubuhlungu besisu, noma ukuqubuka.

Ezinye izingane nentsha ethola umjovo we-etanercept nemithi efanayo yakha umdlavuza onzima noma osongela ukuphila kubandakanya i-lymphoma (umdlavuza oqala kumaseli alwa nokutheleleka). Uma ingane yakho iba nalezi zimpawu phakathi nokwelashwa kwayo, shayela udokotela wayo ngokushesha: ukuncipha kwesisindo okungachazeki; izindlala ezivuvukile entanyeni, ngaphansi kwekhwapha, noma emgodini; noma ukulimaza okulula noma ukopha. Khuluma nodokotela wengane yakho ngezingozi zokufaka umjovo we-etanercept enganeni yakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-etanercept futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-etanercept.

I-Etanercept isetshenziswa yodwa noma neminye imithi yokuqeda izimpawu zezifo ezithile ezizimele (izimo lapho amasosha omzimba ehlasela khona izingxenye ezinempilo zomzimba futhi abangele ubuhlungu, ukuvuvukala nokulimala) kufaka phakathi:

• i-rheumatoid arthritis (isimo lapho umzimba uhlasela khona amalunga ayo, ubangele ubuhlungu, ukuvuvukala, nokulahlekelwa ngumsebenzi) kubantu abadala,
• i-psoriatic arthritis (isimo esidala ubuhlungu bamalunga nokuvuvukala nezikali esikhumbeni) kubantu abadala,
• i-juvenile idiopathic arthritis (i-JIA; isimo esithinta izingane lapho umzimba uhlasela khona amalunga omzimba, ubangele ubuhlungu, ukuvuvukala, ukuphelelwa umsebenzi, nokubambezeleka kokukhula nentuthuko) ezinganeni ezineminyaka emibili ubudala nangaphezulu,
• i-ankylosing spondylitis (isimo lapho umzimba uhlasela khona amalunga omgogodla nezinye izindawo okubangela ubuhlungu nokulimala ngokuhlanganyela),
• i-plaque psoriasis engapheli (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, anezikhala ezindaweni ezithile zomzimba) kubantu abadala nasezinganeni ezineminyaka engu-4 nangaphezulu i-psoriasis yayo enzima kakhulu ukuthi ingalashwa yimithi yokwelapha kuphela.

U-Etanercept usesigabeni semithi ebizwa nge-tumor-necrosis factor (TNF) inhibitors. Isebenza ngokuvimba isenzo se-TNF, into esemzimbeni ebangela ukuvuvukala

Umjovo we-Etanercept uza njengesisombululo (uketshezi) kwisirinji ekhethiwe kanye nedivayisi yomjovo othomathikhi, nanjengempuphu ezohlanganiswa noketshezi olunikeziwe. I-Etanercept ijojowe ngomgogodla (ngaphansi kwesikhumba). Kuvame ukujova kanye ngesonto. Lapho umjovo we-etanercept usetshenziselwa ukwelapha i-plaque psoriasis engapheli, ingajovwa kabili ngesonto ezinyangeni zokuqala ezintathu zokwelashwa bese kuthi kanye ngesonto ngemuva kwezinyanga ezintathu zokuqala. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-etanercept njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Uzothola isilinganiso sakho sokuqala somjovo we-etanercept ehhovisi likadokotela. Ngemuva kwalokho, ungazifaka umuthi ngokwakho ekhaya noma umngane noma isihlobo senze imijovo. Cela udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozokwenza imijovo yokujova i-etanercept. Funda imiyalo ebhaliwe eza nomjovo we-etanercept ngaphambi kokujova umuthi.

Izitsha zomjovo we-etanercept zingaqukatha imithi eyanele yedosi engaphezu kweyodwa. Uma kunemithi eyanele esele esitsheni somthamo ophelele, beka isitsha esiqandisini ngokushesha okukhulu, kodwa kungakapheli amahora ama-4 ngemuva kokukuxuba. Ungagcina umgqomo womjovo we-etanercept kuze kube yizinsuku eziyi-14 ngemuva kokukuxuba uma kukhona imithi eyanele esele yomthamo ophelele. Kodwa-ke, akufanele uhlanganise okuqukethwe izigaxa ezimbili noma ngaphezulu zomjovo we-etanercept ukwenza umthamo ophelele. Akufanele futhi uhlanganise neminye imishanguzo ngomjovo we-etanercept.

Uma umuthi wakho uza ngesirinji ekhethiwe noma ngedivayisi yokujova ezenzekelayo, sebenzisa isirinji ngayinye noma idivaysi kanye kuphela bese ujova sonke isixazululo esirinji noma edivayisini. Noma ngabe kusekhona isixazululo esisele esirinji noma edivayisini, ungasisebenzisi futhi. Lahla izinaliti, imijovo, namadivayisi esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Uma usebenzisa isirinji ekhethiwe, umshini wokujova othomathikhi, noma isitsha esifakwe esiqandisini, beka isirinji, idivaysi, noma isitsha endaweni eyisicaba bese uyivumela ifudumele ekamelweni lokushisa imizuzu eyi-15-30 ngaphambi kokuba ulungele jove umuthi. Ungazami ukufudumeza umuthi ngokuwufudumeza ngemicrowave, uwubeke emanzini ashisayo, noma ngenye indlela.

Unganyakazisi isirinji, umshini wokujova othomathikhi, noma isitsha esine-etanercept. Qaphela ukuthi ungaphonsi ucingo endaweni eqinile ngoba lokhu kungalimaza ucingo, isipetu noma inaliti.

Njalo bheka isixazululo se-etanercept ngaphambi kokusijova. Hlola ukuthi usuku lokuphelelwa yisikhathi aludlulanga nokuthi uketshezi lucacile futhi alunambala. Lolu ketshezi lungaqukatha izinhlayiya ezincane ezimhlophe, kodwa akufanele lube nezinhlayiya ezinkulu noma ezinemibala. Ungasebenzisi isirinji noma ipeni lokufaka imithamo uma iqhekekile noma yephukile, uma iphelelwe yisikhathi, noma uma uketshezi luguqubele noma luqukethe izinhlayiya ezinkulu noma ezinemibala.

Indawo enhle yokujova umjovo we-etanercept ingaphambili lamathanga akho aphakathi. Ungafaka futhi umuthi esiswini sakho esingezansi ngaphansi kwenkaba yakho, ngaphandle kwendawo engama-intshi amabili (amasentimitha ama-5) ezungeze inkaba yakho. Uma omunye umuntu ekujova, lowo muntu angajova umuthi ezingalweni zakho ezingaphezulu. Uma i-etanercept ijojowe ezingalweni noma esiswini esingenhla, isikhumba kuleyo ndawo kufanele silulwe ukuze sakhe indawo eqinile yomjovo. Khetha indawo ehlukile yomjovo ngamunye. Musa ukujova endaweni lapho isikhumba sithambile, silimele, sibomvu, siqinile, noma lapho kunezibazi noma izimpawu zokwelula. Uma une-psoriasis, musa ukujova esikhunjeni esibomvu, esiwugqinsi, esikhuphukile noma esine-scaly.

Umjovo we-Etanercept ungasiza ukulawula isimo sakho kepha ngeke uselaphe. Qhubeka nokusebenzisa umjovo we-etanercept noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa i-etanercept ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-etanercept,

• Tshela udokotela wakho kanye nosokhemisi uma ngabe uxabana ne-etanercept noma eminye imithi. Uma uzosebenzisa isirinji oyikhethile noma umshini wokujova othomathikhi, tshela udokotela wakho uma wena noma umuntu ozokujolela umuthi wena uzwelana nenjoloba noma i-latex.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO, imishanguzo yesifo sikashukela, kanye ne-cyclophosphamide (Cytoxan). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke wahlaselwa yisifo sokuwa noma wake waquleka; isifo esithinta isistimu yakho yezinzwa, njenge-multiple sclerosis (MS; ukulahleka kokuxhumanisa, ubuthakathaka, nokuba ndikindiki ngenxa yokulimala kwezinzwa); transverse myelitis (ukuvuvukala komgogodla okungadala ukuzwa okungavamile, ukulahlekelwa umuzwa, noma ukulahlekelwa amandla okuhambisa umzimba ongezansi); i-optic neuritis (ukuvuvukala kwemizwa ethumela imiyalezo isuka esweni iye ebuchosheni); izinkinga zokopha; isifo sesibindi, noma ukwehluleka kwenhliziyo.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-etanercept, shayela udokotela wakho. Uma usebenzisa umjovo we-etanercept ngesikhathi ukhulelwe, qiniseka ukuthi ukhuluma nodokotela wengane yakho ngalokhu ngemuva kokuzalwa kwengane yakho. Ingane yakho ingadinga ukuthola imigomo ethile sekwedlule isikhathi kunokujwayelekile.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-etanercept.
• awunayo imigomo ngesikhathi sokwelashwa kwakho nge-etanercept ngaphandle kokukhuluma nodokotela wakho. Uma ingane yakho izokwelashwa ngomjovo we-etanercept, khuluma nodokotela wayo ngemigomo okufanele inikezwe ngaphambi kokuqala kokwelashwa. Uma kungenzeka, ingane yakho kufanele inikezwe yonke imigomo edingekayo ezinganeni ezineminyaka yakhe ngaphambi kokuqala ukwelashwa.
• uma uchayeka ku-chickenpox ngenkathi usebenzisa i-etanercept, shayela udokotela wakho ngokushesha.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Jova umthamo ophuthelwe ngokushesha nje lapho uwukhumbula. Uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka nesimiso sakho sokulinganisa esivamile. Musa ukujova umthamo ophindwe kabili ukwenzela okulahlekile.

I-Etanercept ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ububomvu, ukulunywa, ubuhlungu, noma ukuvuvukala endaweni yomjovo
• ikhanda
• isicanucanu
• ukuhlanza
• isilungulela
• ubuhlungu besisu
• ubuthakathaka
• ukukhwehlela

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana neminye yale miphumela engemihle elandelayo noma leyo eshiwo ESIGXWAYINI ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole usizo oluphuthumayo lwezokwelapha:

• isithuthwane
• ukulinyazwa
• ukopha
• isikhumba esiphaphathekile
• isikhumba esiqhumayo
• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuphefumula kanzima noma ukugwinya
• ukuqubuka ebusweni nasezingalweni okuba kubi kakhulu elangeni
• ukuba ndikindiki noma ukuhayiza
• izinkinga zokubona
• ubuthakathaka ezandleni noma emilenzeni
• isiyezi
• okubomvu, amabala anezikhala noma amaqhuqhuva agcwaliswa ubomvu esikhunjeni

Abantu abadala abathola umjovo we-etanercept mhlawumbe basengozini enkulu yokuthola i-lymphoma, i-leukemia (umdlavuza oqala kumaseli amhlophe egazi), umdlavuza wesikhumba, nezinye izinhlobo zomdlavuza kunabantu abadala abangawutholi lo muthi. Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-etanercept.

Umjovo we-Etanercept ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina umjovo we-etanercept esiqandisini kepha ungafrizi. Gcina izitsha, imijovo ekhethiwe, noma okokujova emabhokisini abo okuqala ukuzivikela ekukhanyeni. Uma uxube i-vial ye-etanercept powder noketshezi olunikeziwe, ungagcina isixazululo esiqandisini izinsuku ezifika kwezili-14.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-etanercept.

Ngaphambi kokwenza noma yiluphi uvivinyo lwe-laboratory, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi usebenzisa i-etanercept.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Umhlanganisi^®