I-Aprepitant

-Delile

• Ngaphambi kokuthatha i-aprepitant,
• I-Aprepitant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Aprepitant isetshenziswa neminye imithi kubantu abadala nasezinganeni enezinyanga eziyisithupha ubudala nangaphezulu ukuvimbela isicanucanu nokuhlanza okungenzeka ngemuva kokuthola ukwelashwa ngamakhemikhali omdlavuza. Ibuye isetshenziswe neminye imithi kubantu abadala nasezinyangeni ezineminyaka engu-6 nangaphezulu ukuvimbela ukubuyisa isicanucanu nokuhlanza okungenzeka ezinsukwini ezimbalwa ngemuva kokuthola imishanguzo ethile yamakhemikhali. I-Aprepitant ayisetshenziselwa ukwelapha isicanucanu nokuhlanza osunayo. I-Aprepitant isesigabeni semithi ebizwa ngama-antiemetics. Isebenza ngokuvimba isenzo se-neurokinin, into yemvelo ebuchosheni ebangela isicanucanu nokuhlanza.

I-Aprepitant iza njenge-capsule nanjengokumiswa ngomlomo (uketshezi) ukuthatha ngomlomo. Ukuvimbela isicanucanu nokuhlanza okubangelwa i-chemotherapy yomdlavuza, i-aprepitant imvamisa ithathwa kanye ngosuku, noma ngaphandle kokudla, ezinsukwini zokuqala ezimbalwa zokwelashwa komdlavuza wakho womdlavuza. Mhlawumbe uzothatha i-aprepitant 1 ihora ngaphambi kwe-chemotherapy yakho ngezinsuku 1, 2, no-3 zokwelashwa kwakho. Uma ungatholi i-chemotherapy ngezinsuku 2 no-3, khona-ke uzothatha i-aprepitant ngalezo zinsuku ekuseni. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-aprepitant njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Ama-aprepitant capsules eza ngamandla amabili ahlukene. Udokotela wakho angakunika womabili la mandla ongawathatha ngezikhathi ezahlukahlukene. Kufanele uqaphele ukuthatha amandla afanele ngesikhathi esifanele njengokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Ukumiswa ngomlomo kuzolungiswa ngumhlinzeki wakho wezokunakekelwa kwezempilo futhi akunikezwe kumshini wokuhambisa ngomlomo. Gcina okokuhambisa ngomlomo esiqandisini kuze kufike isikhathi sethamo lakho; noma kunjalo, ingagcinwa ekamelweni lokushisa kuze kube amahora amathathu ngaphambi kokuyisebenzisa. Lapho usukulungele ukuyisebenzisa, susa ikepisi kudispenser ngaphambi kokuyifaka emlonyeni wakho ukuze ukhiphe umuthi kancane.

I-Aprepitant isebenza kuphela ukuvimbela isicanucanu nokuhlanza. Shayela udokotela wakho uma usuvele unalezi zimpawu futhi ungaqali ukuthatha i-aprepitant.

Lapho isetshenziselwa ukuvimbela isicanucanu nokuhlanza okubangelwa i-chemotherapy yomdlavuza, i-aprepitant ivame ukusetshenziswa kuphela ezinsukwini ezi-3 zokuqala zemijikelezo yokwelashwa ngamakhemikhali. Ungaqhubeki uphuza i-aprepitant isikhathi eside kunokuyalelwa ngudokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-aprepitant,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-aprepitant, noma imiphi eminye imithi, noma iziphi izithako ezikuma-aprepitant capsules noma ukumiswa ngomlomo. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• ungathathi i-aprepitant uma uthatha i-pimozide (Orap). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-aprepitant uma uthatha lo muthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); ama-antifungal anjenge-itraconazole (i-Onmel, i-Sporanox) ne-ketoconazole; ama-benzodiazepines afana ne-alprazolam (Xanax), i-diazepam (i-Valium), i-midazolam ne-triazolam (i-Halcion); imishanguzo yomdlavuza ngamakhemikhali afana ne-ifosfamide (Ifex), irinotecan (Camptosar), vinblastine, ne-vincristine (Marqibo Kit); i-carbamazepine (i-Equetro, iTegretol, iTeril); i-clarithromycin (i-Biaxin, ku-Prevpac); i-diltiazem (iCardizem, iCartia, iTiazac); I-HIV protease inhibitors efana ne-nelfinavir (i-Viracept) ne-ritonavir (i-Norvir); izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula inzalo, amabala, izindandatho nemijovo); nefazodone; i-steroids yomlomo efana ne-dexamethasone ne-methylprednisolone (Medrol); i-phenytoin (iDilantin, Phenytek); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); ne-troleandomycin (TAO; ayisatholakali e-U.S.). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-aprepitant, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma uthatha noma uthola izindlela zokuvimbela inzalo ze-hormonal (amaphilisi okulawula ukubeletha, amapeshi, izindandatho, okufakelwa, noma imijovo) ngenkathi welashwa nge-aprepitant, kufanele futhi usebenzise enye indlela yokulawula inzalo (i-spermicide, ikhondomu) ukugwema ukukhulelwa ngesikhathi sokwelashwa nge-aprepitant kanye inyanga eyodwa ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ngenkathi uthatha i-aprepitant nangemva kokwelashwa. Uma ukhulelwa ngenkathi uthatha i-aprepitant, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Aprepitant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuthakathaka
• ukukhathala
• isiyezi
• isifo sohudo
• ukuqunjelwa
• igesi
• ubuhlungu besisu
• isilungulela
• isicanucanu
• izinqa
• ukulahlekelwa isifiso sokudla
• ikhanda
• imfiva
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukuxebuka kwesikhumba noma amabhamuza
• ukuphefumula kanzima noma ukugwinya

I-Aprepitant ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amaphilisi ekamelweni lokushisa kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Umthamo wokumiswa ngomlomo olungiselelwe kufanele usetshenziswe kungakapheli amahora angama-72 wokulungiselela; lahla noma yimiphi imithamo engasetshenziswanga ngemuva kwamahora angama-72.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukozela
• ikhanda

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Hlela^®