Umlobi: Gregory Harris
Usuku Lokudalwa: 9 Epreli 2021
Ukuvuselela Usuku: 21 Unovemba 2024
Anonim
Oral nanatinostat and valganciclovir for EBV-associated lymphomas
Ividiyo: Oral nanatinostat and valganciclovir for EBV-associated lymphomas

-Delile

IValganciclovir ingehlisa inani lamaseli abomvu egazi, amaseli amhlophe egazi, nama-platelet emzimbeni wakho, okudala izinkinga ezinkulu nezisongela impilo. Tshela udokotela wakho uma ngabe uke waba nenombolo ephansi yamaseli abomvu egazi, amaseli amhlophe egazi, noma ama-platelets; noma ezinye izinkinga zegazi noma zokopha. Tshela udokotela wakho uma uke waba nezinkinga zegazi njengomphumela oseceleni womuthi ofana ne-valganciclovir efana ne-ganciclovir (iCytovene). Futhi, tshela udokotela kanye nosokhemisi wakho uma uthatha noma uphuzile noma iyiphi yale mithi elandelayo: imithi yokwelapha ngamakhemikhali efana ne-doxorubicin (Doxil), i-vinblastine, ne-vincristine; dapsone; i-flucytosine (Ancobon); i-hydroxyurea (iDroxia, iSiklos); ama-immunosuppressants anjenge-cyclosporine (Gengraf, Neoral, Sandimmune) kanye ne-tacrolimus (Prograf); imithi yokwelapha igciwane lesandulela ngculazi (i-HIV) kanye ne-immunodeficiency syndrome (i-AIDS) okubandakanya i-didanosine (Videx) noma i-zidovudine (Retrovir, AZT); ipentamidine (NebuPent, Pentam); i-trimethoprim / sulfamethoxazole (Bactrim, Septra); noma uma uthola noma uthola ukwelashwa ngemisebe (i-X-ray). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukukhathala ngokweqile; ubuthakathaka; isikhumba esiphaphathekile; isiyezi; ukudideka; ukushaya kwenhliziyo okusheshayo; ubunzima bokulala noma ukulala; ukuphelelwa umoya; ukopha okungavamile noma ukulimaza; noma umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka.


IValganciclovir ingalimaza umbungu. Ungathathi i-valganciclovir uma ukhulelwe noma uhlela ukukhulelwa. Uma ungowesifazane, kuzodingeka uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nezinsuku ezingama-30 ngemuva komthamo wakho wokugcina. Uma ungowesilisa futhi umlingani wakho angakhulelwa, kufanele usebenzise ikhondomu ngenkathi uthatha lo muthi nezinsuku ezingama-90 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho uma unemibuzo mayelana nokulawulwa kokuzalwa. Uma ukhulelwa ngenkathi uthatha i-valganciclovir, shayela udokotela wakho ngokushesha.

IValganciclovir inganciphisa okwesikhashana noma unomphela ukuzala kwabesilisa nabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha i-valganciclovir.

Izilwane zaselabhorethri ezinikezwe i-valganciclovir zaba nomdlavuza. Akwaziwa ukuthi i-valganciclovir inyusa ingozi yomdlavuza kubantu.

Gcina konke ukubonana nodokotela wakho, udokotela wamehlo, kanye nelabhorethri. Odokotela bakho banga-oda izivivinyo zamehlo ezivamile nokuhlolwa okuthile ukuze uhlole impendulo yomzimba wakho ku-valganciclovir.


Khuluma nodokotela wakho ngezingozi zokuthatha i-valganciclovir.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi wesiguli bese uyifunda ngokucophelela ngaphambi kokuba uqale ukusebenzisa le mithi futhi isikhathi ngasinye lapho ugcwaliswa khona.

IValganciclovir isetshenziselwa ukwelapha i-cytomegalovirus (CMV) retinitis (ukutheleleka kwamehlo okungadala ubumpumputhe) kubantu abathole i-immunodeficiency syndrome (i-AIDS). IValganciclovir ibuye isetshenziselwe ukuvikela isifo se-cytomegalovirus (CMV) kubantu abathole ukufakelwa kwenhliziyo, izinso, noma izinso-pancreas futhi abasethubeni lokuthola isifo se-CMV. UValganciclovir usesigabeni semithi ebizwa ngama-antivirals. Isebenza ngokuvimbela ukusabalala kwesifo se-CMV noma ukunciphisa ukukhula kwe-CMV.

IValganciclovir iza njengethebhulethi nanjengesisombululo somlomo (uketshezi) ukuthatha ngomlomo. Imvamisa kuthathwa ngokudla kanye noma kabili ngosuku. Ukukusiza ukuthi ukhumbule ukuthatha i-valganciclovir, yithathe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-valganciclovir njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.


Izingane zingathatha amaphilisi noma isisombululo somlomo; noma kunjalo, abantu abadala kufanele kuphela thatha amaphilisi.

Isixazululo somlomo sizolungiswa ngusokhemisi wakho futhi bazokunikeza nensimbi yokukala umthamo wakho. Sebenzisa kuphela idivayisi yokulinganisa oyinikezwe ukukala isixazululo sakho.

Nyakazisa isisombululo somlomo ngaphambi kokusetshenziswa ngakunye.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune, ungawaphuli noma uwagaye.

Qaphela lapho uphatha amaphilisi e-valganciclovir noma isisombululo somlomo. Ungavumeli isikhumba sakho, amehlo, umlomo, noma ikhala ukuthi kuhlangane namaphilisi e-valganciclovir aphukile noma achotshoziwe noma isisombululo somlomo. Uma ukuthintana okunjalo kwenzeka, geza isikhumba sakho kahle ngensipho namanzi noma ugeze amehlo akho kahle ngamanzi alula.

IValganciclovir iyasiza ukulawula i-CMV kepha ayiyelaphi. Ungayeki ukuthatha i-valganciclovir ngaphandle kokukhuluma nodokotela wakho. Ukuyeka ukuthatha i-valganciclovir maduze kungadala ukuthi inani le-CMV egazini lakho lenyuke noma igciwane lingazweli kulo muthi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-valganciclovir,

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-valganciclovir, ganciclovir (Cytovene), noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-valganciclovir noma kwisisombululo somlomo. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SEXWAYISO nakokulandelayo: i-amphotericin B (i-Abelcet, i-Ambisome); imipenem-cilastatin (Primaxin); i-mycophenolate mofetil (CellCept); kanye ne-probenecid. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • Tshela udokotela wakho uma uke waba nezimo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO noma eminye yale mibandela elandelayo: isifo sezinso noma sesibindi, noma uma welashwa nge-hemodialysis (umshini okhethekile osusa imfucuza egazini).
  • tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-valganciclovir. Khuluma nodokotela wakho mayelana nokuthi ungaqala nini ukuncelisa ngokuphepha ngemuva kokuyeka ukuthatha i-valganciclovir.
  • uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-valganciclovir.
  • kufanele wazi ukuthi i-valganciclovir ingakwenza ukozele, ube nesiyezi, ungazinzi, udideke, ungaqapheli kakhulu, noma ubangele ukuqumba. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.

Phuza uketshezi oluningi ngenkathi uthatha i-valganciclovir.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Bese uthatha umthamo olandelayo ngesikhathi esijwayelekile esihleliwe. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IValganciclovir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • isifo sohudo
  • isicanucanu
  • ukuhlanza
  • ubuhlungu, ubumnene, noma ukuvuvukala kwesisu
  • ubuhlungu beso
  • ukuqunjelwa
  • ikhanda
  • ukuncipha komzimba
  • iqolo, ukuhlangana, noma ubuhlungu bemisipha
  • izilonda zomlomo
  • ukudana
  • ukukhathazeka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

  • ukubona amachashazi, ukukhanya, noma ikhethini elimnyama phezu kwakho konke
  • ukuncipha kokuchama
  • igazi emchameni
  • izinkinga zokubona
  • ukuvuvukala kwezandla, izingalo, izinyawo, amaqakala, noma imilenze engezansi
  • isifuba
  • ukuqubuka
  • ukulunywa
  • ukuphuzi kwesikhumba noma kwamehlo; ukulahlekelwa ukudla; umchamo omnyama; kanye / noma ukunyakaza kwamathumbu anombala okhanyayo
  • ukunyakaza okungahlosile noma ukunyakazisa
  • ukuba ndikindiki, ubuhlungu, ukushiswa, noma ukushosheka ezandleni noma ezinyaweni
  • isithuthwane

IValganciclovir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amaphilisi ekamelweni lokushisa kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Gcina isisombululo somlomo esiqandisini izinsuku ezifika kwezingama-49 ku-2-8 ° C; ungafrizi.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

  • isisu esibuhlungu
  • ukuhlanza
  • ubuhlungu besisu
  • isifo sohudo
  • ukuxhawula izandla ongeke ukwazi ukuzilawula
  • isithuthwane
  • ukuncipha kokuchama
  • umchamo onegazi
  • umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka
  • ukukhathala ngokweqile
  • isikhumba esiphaphathekile
  • ukuphuzi kwesikhumba noma kwamehlo
  • isiyezi
  • ukushaya kwenhliziyo okusheshayo
  • ubuthakathaka
  • ukopha okungajwayelekile noma ukulinyazwa

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Ungavumeli ukunikezelwa kwe-valganciclovir yakho kuphele. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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