Injection ye-Ondansetron

-Delile

• Ngaphambi kokusebenzisa i-ondansetron,
• I-Ondansetron ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma ufune ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo we-Ondansetron usetshenziselwa ukuvikela isicanucanu nokuhlanza okubangelwa umdlavuza ngamakhemikhali nokwelashwa. I-Ondansetron isekilasini lemithi ebizwa nge-serotonin 5-HT₃ abaphikisi be-receptor. Isebenza ngokuvimba isenzo se-serotonin, into yemvelo engadala isicanucanu nokuhlanza.

I-Ondansetron iza njengesisombululo (uketshezi) ukujova ngomjovo (emthanjeni) noma nge-intramuscularly (emsipheni) ngumhlinzeki wezokunakekelwa kwempilo esibhedlela noma emtholampilo. Lapho i-ondansetron isetshenziselwa ukuvimbela isicanucanu nokuhlanza okubangelwa i-chemotherapy, imvamisa inikezwa imizuzu engama-30 ngaphambi kokuqala kwe-chemotherapy. Imithamo eyengeziwe inganikezwa amahora ama-4 ngemuva komthamo wokuqala we-ondansetron namahora ayi-8 ngemuva komthamo wokuqala we-ondansetron, uma kudingeka. Lapho i-ondansetron isetshenziselwa ukuvimbela isicanucanu nokuhlanza okubangelwa ukuhlinzwa, imvamisa inikezwa ngaphambi nje kokuhlinzwa. I-Ondansetron nayo kwesinye isikhathi inikezwa ngemuva kokuhlinzwa ezigulini ezinesicanucanu nokuhlanza futhi ezingazange zithole i-ondansetron ngaphambi kokuhlinzwa.

Lo muthi ungabekelwa okunye ukusetshenziswa. Buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-ondansetron,

• Tshela udokotela kanye nosokhemisi wakho uma uxabana ne-ondansetron, i-alosetron (Lotronex), i-dolasetron (i-Anzemet), i-granisetron (i-Kytril), i-palonosetron (i-Aloxi), noma yimuphi omunye umuthi: noma iziphi izithako zomjovo we-ondansetron. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthola i-apomorphine (Apokyn). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi i-ondansetron uma uthola lo muthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Cordarone, Pacerone); i-azithromycin (iZithromax); imithi ethile yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), noma phenytoin (Dilantin); i-chloroquine (Aralen); i-chlorpromazine; i-citalopram (Celexa); i-clarithromycin (i-Biaxin, ku-Prevpac); isisu (‘amaphilisi amanzi’); i-erythromycin (E.E.S., Erythrocin, abanye); i-fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); flecainide; i-haloperidol (iHaldol); i-lithium (i-Lithobid); imithi yokwelapha i-migraines efana ne-almotriptan (Axert), i-eletriptan (i-Relpax), i-frovatriptan (i-Frova), i-naratriptan (i-Amerge), i-rizatriptan (i-Maxalt), i-sumatriptan (i-Imitrex), ne-zolmitriptan (iZomig); i-methylene eluhlaza okwesibhakabhaka; i-mirtazapine (i-Remeron); i-monoamine oxidase (MAO) inhibitors kufaka phakathi i-isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ne-tranylcypromine (iParnate); moxifloxacin (Avelox); ipentamidine (Nebu-Pent); ipimozide (i-Orap); procainamide; i-quinidine; i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); i-serotonin / norepinephrine reuptake inhibitors ekhethiwe (i-SNRIs) efana ne-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), ne-venlafaxine (Effexor XR); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-escitalopram (Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, e-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-sertraline (i-Zoloft); i-sotalol (iBetapace, iSorine); thioridazine; i-tramadol (i-Conzip, i-Ultram, ku-Ultracet); kanye ne-vandetanib (Caprelsa). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-ondansetron, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo se-QT eside (isimo esandisa ingozi yokuba nokushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzuma), noma olunye uhlobo lokushaya kwenhliziyo okungajwayelekile noma inkinga yesigqi senhliziyo, noma uma uke waba namazinga aphansi we-magnesium noma i-potassium egazini lakho, ukwehluleka kwenhliziyo (HF; isimo lapho inhliziyo ingakwazi ukupompa igazi elanele kwezinye izingxenye zomzimba), noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola i-ondansetron, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla kwakho okujwayelekile.

I-Ondansetron ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukuqunjelwa
• ukozela
• ukuzwa amakhaza noma amakhaza
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza esandleni noma ezinyaweni
• imfiva
• umjovo wesiza somjovo, ubomvu, ukuvuvukala, imfudumalo, noma ukuvutha

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma ufune ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya
• ubuhlungu besifuba
• ukuphelelwa umoya
• isiyezi, ikhanda elikhanyayo, noma ukuquleka
• ukushaya kwenhliziyo okusheshayo, okuhamba kancane noma okungajwayelekile
• ukungaboni kahle noma ukulahleka kombono
• ubumhlophe
• ukuyaluza
• ukusangana (ukubona izinto noma ukuzwa amazwi angekho)
• imfiva
• ukujuluka okweqile
• ukudideka
• isicanucanu, ukuhlanza, noma isifo sohudo
• ukulahleka kokuxhumanisa
• imisipha eqinile noma eshwibayo
• isithuthwane
• ikhoma (ukulahlekelwa ukwazi)

I-Ondansetron ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa le mithi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Lo muthi uzogcinwa esibhedlela noma emtholampilo.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukulahleka okungazelelwe kombono isikhashana
• isiyezi noma ikhanda elikhanyayo
• ukuquleka
• ukuqunjelwa
• ukushaya kwenhliziyo okungajwayelekile

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UZofran^® Ukujova