I-Rotigotine Transdermal Patch

-Delile

• Ukufaka isichibi, landela lezi zinyathelo:
• Ngaphambi kokusebenzisa isichibi se-rotigotine,
• I-Rotigotine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

Ama-Rotigotine transdermal patches asetshenziselwa ukwelapha izimpawu nezimpawu zesifo sikaParkinson's (PD; ukuphazamiseka kwesistimu yezinzwa okubangela ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela) kufaka phakathi ukuzamazama kwezingxenye zomzimba, ukuqina, ukunyakaza okuhamba kancane, nezinkinga ngebhalansi. Ama-Rotigotine transdermal patches nawo asetshenziselwa ukwelapha imilenze engazinzi (i-RLS noma i-Ekbom syndrome; isimo esidala ukungakhululeki emilenzeni kanye nesifiso esinamandla sokuhambisa imilenze, ikakhulukazi ebusuku nalapho uhleli noma ulele phansi). I-Rotigotine isekilasini lemithi ebizwa ngama-dopamine agonists. Isebenza ngokusebenza esikhundleni se-dopamine, into yemvelo ekhiqizwa ebuchosheni edingekayo ukulawula ukunyakaza.

I-Transdermal rotigotine iza njengesichibi esizosebenza esikhunjeni. Ngokuvamile kufakwa kanye ngosuku. Faka isichibi se-rotigotine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-rotigotine njengoba nje kuqondisiwe.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-rotigotine futhi akhuphule kancane umthamo wakho, hhayi kaningi ngesonto.

IRotigotine ilawula izimpawu zesifo sikaParkinson nesifo semilenze esingenakuphumula kodwa ayizelaphi. Kungathatha amasonto ambalwa ngaphambi kokuba uzwe inzuzo ephelele ye-rotigotine. Qhubeka nokusebenzisa ama-rotigotine patches noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa ama-rotigotine transdermal patches ngaphandle kokukhuluma nodokotela wakho. Uma ngokungazelelwe uyeka ukusebenzisa ama-rotigotine patches, ungahle ube nomkhuhlane, ukuqina kwemisipha, ushintshe ukwazi, noma ezinye izimpawu. Udokotela wakho mhlawumbe uzokwehlisa umthamo wakho kancane kancane.

Faka isichibi endaweni esiswini, ethangeni, enqulwini, ohlangothini (ohlangothini lomzimba phakathi kwezimbambo nokhalo), ihlombe, noma ingalo engaphezulu. Indawo yesikhumba kufanele ihlanzeke, yomile futhi iphilile. Ungafaki isichibi esikhunjeni esinamafutha, esibomvu, esicasukile noma esilimele. Ungasebenzisi okhilimu, ama-lotion, amafutha okugcoba, uwoyela, noma izimpushana endaweni yesikhumba lapho kuzobekwa khona isichibi. Ungasifaki isichibi emaphethweni esikhumba nasezindaweni zesikhumba ezingaba ngaphansi kwebhande noma zigcotshwe izingubo eziqinile. Uma isichibi sizosetshenziswa endaweni enoboya, gunda indawo okungenani izinsuku ezintathu ngaphambi kokufaka isichibi. Khetha indawo ehlukile yesikhumba usuku ngalunye njengokushintsha kusuka ohlangothini lwesokudla uye kwesobunxele noma ngokuhamba emzimbeni ongaphezulu uye emzimbeni ongezansi. Ungasifaki isichibi se-rotigotine endaweni efanayo yesikhumba kaningi kaningi ezinsukwini eziyi-14.

Ngenkathi ugqoke isichibi, gcina indawo ikude neminye imithombo yokushisa njengamaphakethe okushisa, izingubo zokulala zikagesi nemibhede yamanzi efudumele; noma ilanga eliqondile. Ungagezi ngamanzi ashisayo noma usebenzise i-sauna.

Qaphela ukuthi ungakhiphi isichibi ngesikhathi sokugeza noma somzimba. Uma imiphetho ye-patch lift, sebenzisa i-tape ye-bandage ukuyivikela kabusha esikhumbeni. Uma i-patch iwa, faka isichibi esisha endaweni ehlukile esikhunjeni sakho usuku lonke. Ngosuku olulandelayo, susa leso sichibi bese usebenzisa isichibi esisha ngesikhathi esijwayelekile.

Uma indawo yesikhumba ebimbozwe yisiqeshana icasuka noma iba namaqubu, ungayivezi le ndawo ekukhanyeni kwelanga kuze kuphole isikhumba. Ukuvezwa kwale ndawo elangeni kungadala ushintsho kumbala wesikhumba sakho.

Ungasiki noma ulimaze isichibi se-rotigotine.

Ukufaka isichibi, landela lezi zinyathelo:

1. Bamba izinhlangothi ezimbili zesikhwama bese uyahlukana.
2. Susa isichibi esikhwameni. Faka isichibi ngokushesha ngemuva kokukususa esikhwameni esivikelayo.
3. Bamba isichibi ngezandla zombili, ne-liner evikelayo ngaphezulu.
4. Gobisa imiphetho yesiqeshana kude nawe ukuze ukusika okumise okwe-S ku-liner kuvuleke.
5. Susa ikhasi elilodwa le-liner evikelayo. Ungayithinti indawo enamathele ngoba umuthi ungavela eminweni yakho.
6. Faka isigamu esinamathelayo se-patch endaweni ehlanzekile yesikhumba bese ususa i-liner esele.
7. Cindezela i-patch ngokuqinile ngentende yesandla sakho amasekhondi angama-30. Zungeza imiphetho ngeminwe yakho ukuze ucindezele esikhunjeni. Qiniseka ukuthi isichibi siyisicaba maqondana nesikhumba (akumele kube khona izigaxa noma amafolda esiqeshini).
8. Ngemuva kokufaka isichibi esisha, qiniseka ukuthi ususa isichibi osukwini lwangaphambilini. Sebenzisa iminwe yakho ukuyihluba kancane. Songa i-patch ngesigamu bese ucindezela ngokuqinile ukuyivala. Yilahle ngokuphepha, ukuze ingafinyeleleki ezinganeni nasezifuyweni.
9. Uma kukhona okunamathelayo okusele esikhunjeni, geza ngobumnene indawo ngamanzi afudumele nensipho emnene noma gcoba leyo ndawo ngoyela wengane noma wamaminerali ukuze uyisuse.
10. Geza izandla zakho ngensipho namanzi. Ungathinti amehlo akho noma ezinye izinto uze ugeze izandla.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa isichibi se-rotigotine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-rotigotine, i-sulfite, noma yimuphi omunye umuthi, noma iziphi izithako ezikuma-rotigotine transdermal patches. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo, imishanguzo yokukhathazeka, imishanguzo yokugula ngengqondo, imishanguzo yokuxhuzula, i-metoclopramide (Reglan), imishanguzo yokuthambisa, amaphilisi okulala, nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma une-asthma, umfutho wegazi ophakeme noma ophansi, ukugula ngengqondo, ukulala emini ngenxa yokuphazamiseka kokulala noma uma uke waba nezikhathi zokulala ngokuzuma futhi ngaphandle kwesixwayiso emini noma kwesifo senhliziyo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-rotigotine, shayela udokotela wakho.
• kufanele wazi ukuthi i-rotigotine ingakwenza ukozele noma ingakwenza ukuthi ulale ngokuzumayo phakathi kwemisebenzi yakho ejwayelekile yansuku zonke. Ungase ungazweli ukozela ngaphambi kokuba ulale ngokuzumayo. Ungashayeli imoto noma usebenzise imishini ekuqaleni kokwelashwa kwakho uze wazi ukuthi umuthi ukuthinta kanjani. Uma uvele ulale ngokuzumayo ngenkathi wenza okuthile njengokubuka ithelevishini noma ukugibela emotweni, noma uma wozela kakhulu, shayela udokotela wakho ucingo. Ungashayeli noma usebenzise imishini uze ukhulume nodokotela wakho.
• khumbula ukuthi utshwala bungangezela ukozela okubangelwa yilomuthi. Tshela udokotela wakho uma uphuza njalo utshwala.
• kufanele wazi ukuthi i-rotigotine ingadala isiyezi, ikhanda elikhanyayo, ukuquleka, noma ukujuluka lapho uvuka ngokushesha okukhulu endaweni yokulala. Lokhu kuvame kakhulu lapho uqala ukusebenzisa i-rotigotine noma njengoba umthamo uyanda. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi umfutho wegazi wakho ungakhuphuka ngenkathi welashwa nge-rotigotine. Udokotela wakho mhlawumbe uzoqapha ukucindezelwa kwakho kwegazi ngesikhathi sokwelashwa kwakho.
• kufanele wazi ukuthi i-transdermal rotigotine ingadala ukusha esikhunjeni sakho uma une-magnetic resonance imaging (i-MRI; inqubo ye-radiology eyenzelwe ukukhombisa izithombe zezakhiwo zomzimba) noma i-cardioversion (inqubo yokwenza isigqi senhliziyo sijwayele). Tshela udokotela wakho ukuthi usebenzisa i-transdermal rotigotine uma uzoba nenye yalezi zinqubo.
• kufanele wazi ukuthi abanye abantu abasebenzisa imishanguzo efana ne-transdermal rotigotine bahlakulele imikhuba noma isimilo esinamandla noma esingajwayelekile kubo, njengokugembula, ukukhuphula izifiso zocansi noma isimilo, ukuthenga ngokweqile nokudla ngokweqile. Shayela udokotela wakho uma unesifiso esinamandla sokuthenga, ukudla, ukuya ocansini, noma ukugembula, noma awukwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Sebenzisa umthamo ongabanjwanga (isichibi) ngokushesha nje lapho usikhumbula, bese ufaka isichibi esisha ngesikhathi esijwayelekile ngosuku olulandelayo. Ungafaki isichibi esithe xaxa ukwenzela umthamo ophuthelwe.

I-Rotigotine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqubuka, ukuba bomvu, ukuvuvukala noma ukulunywa kwesikhumba ebesimbozwe yisiqephu
• isicanucanu
• ukuhlanza
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ukozela
• ubunzima bokulala noma ukulala
• amaphupho angajwayelekile
• isiyezi noma ukuzwa ukuthi wena noma igumbi liyahamba
• ikhanda
• ukuquleka
• ukuzuza kwesisindo
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukujuluka okwandayo
• umlomo owomile
• ukulahlekelwa amandla
• ubuhlungu obuhlangene
• umbono ongavamile
• ukunyakaza okungazelelwe kwemilenze noma ukwanda kwezimpawu zePD noma i-RLS
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:

• ukuphefumula kanzima noma ukugwinya
• isifuba
• ukuqubuka
• ukulunywa
• ukubona izinto noma ukuzwa amazwi angekho (hallucinating)
• uzizwe usola ngokungavamile abanye
• ukudideka
• isimilo esinolaka noma esingenabo ubungani
• ukuba nemicabango noma izinkolelo eziyinqaba ezingenasisekelo eqinisweni
• ukuyaluza
• ukuthukuthela noma ukujabula ngokweqile

Abantu abanesifo sika-Parkinson bangaba nengozi enkulu yokuthola i-melanoma (uhlobo lomdlavuza wesikhumba) kunabantu abangenaso isifo sika-Parkinson. Akukho lwazi olwanele ukusho ukuthi imishanguzo esetshenziselwa ukwelapha isifo sikaParkinson njenge-rotigotine iyayandisa yini ingozi yokuba nomdlavuza wesikhumba. Kufanele ube nokuhlolwa kwesikhumba okujwayelekile ukuhlola i-melanoma ngenkathi usebenzisa i-rotigotine noma ngabe awunaso isifo sikaParkinson. Khuluma nodokotela wakho ngengozi yokusebenzisa i-rotigotine.

I-Rotigotine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esikhwameni sokuqala efikile, futhi lapho izingane zingafinyeleli khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma othile efaka iziqeshana ezingeziwe ze-rotigotine, susa amachashazi. Bese ushayele isikhungo sakho sendawo sokulawula ubuthi ku-1-800-222-1222. Uma isisulu siwile noma singaphefumuli, shayela abezimo eziphuthumayo zendawo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu
• ukuhlanza
• ukuquleka
• isiyezi
• ubumhlophe
• ukunyakaza okunzima ukulawula
• ukubona izinto noma ukuzwa amazwi angekho (hallucinating)
• ukudideka
• isithuthwane

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Neupro^®