I-Onabotulinumtoxin Injection

-Delile

• InabotulinumtoxinA injection (Botox) is used to
• InabotulinumtoxinA injection (Botox Cosmetic) is used to
• Ngaphambi kokuthola umjovo we-onabotulinumtoxinA,
• Umjovo we-OnabotulinumtoxinAngadala imiphumela emibi. Buza udokotela wakho ukuthi imiphi imiphumela emibi ongase uyithole, ngoba eminye imiphumela emibi ingavela kaningi engxenyeni yomzimba lapho uthole khona umjovo. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, nganoma yisiphi isikhathi phakathi kwamasonto ambalwa okuqala ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile ngokuvamile aziveli ngemuva kokuthola umjovo. Uma uthola i-onabotulinumtoxinA eningi kakhulu noma uma ugwinya umuthi, tshela udokotela wakho ngaso leso sikhathi futhi utshele udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo emasontweni ambalwa alandelayo:

Umjovo we-Onabotulinumtoxin Umjovo unikezwa njengemijovo emincane ehlose ukuthinta kuphela indawo ethile lapho kujovwe khona.Kodwa-ke, kungenzeka ukuthi umuthi ungasakazeka usuka endaweni yomjovo futhi uthinte imisipha kwezinye izindawo zomzimba. Uma kuthintekile imisipha elawula ukuphefumula nokugwinya, ungahle ube nezinkinga ezinzima zokuphefumula noma ukugwinya okungathatha izinyanga ezimbalwa futhi kungadala ukufa. Uma unenkinga yokugwinya, ungadinga ukondliwa ngepayipi lokudla ukuze ugweme ukuthola ukudla noma isiphuzo emaphashini akho.

Umjovo we-OnabotulinumtoxinUmjovo ungasabalala futhi ubangele izimpawu kubantu banoma yibuphi ubudala abelashelwa noma yisiphi isimo, yize kungekho noyedwa oseke wazakhela lezi zimpawu ngemuva kokuthola umuthi ngemithamo enconyelwe ukwelapha imibimbi, izinkinga zamehlo, ikhanda elibuhlungu, noma ukujuluka okukhulu kwekhwapha. Ingozi yokuthi umuthi uzosakazeka ngale kwendawo yokujova cishe iphezulu kakhulu ezinganeni ezilashelwa ukuqina (ukuqina kwemisipha nokuqina) nakubantu, abake baba nezinkinga zokugwinya, noma zokuphefumula, njenge-asthma noma i-emphysema; noma yisiphi isimo esithinta imisipha noma izinzwa ezifana ne-amyotrophic lateral sclerosis (i-ALS, isifo sikaLou Gehrig; isimo lapho izinzwa ezilawula ukunyakaza kwemisipha zifa kancane kancane, okwenza izicubu zinciphe futhi zenze buthakathaka), motor neuropathy (isimo lapho imisipha iba buthaka khona ngokuhamba kwesikhathi), i-myasthenia gravis (isimo esibangela ukuba imisipha ethile ibe buthakathaka, ikakhulukazi ngemuva komsebenzi), noma i-Lambert-Eaton syndrome (isimo esidala ubuthakathaka bemisipha obungathuthuka ngomsebenzi). Tshela udokotela wakho uma ngabe uke waba nanoma yiziphi zalezi zimo.

Ukusabalala kwe-onabotulinumtoxinUkujova ezindaweni ezingalashwa kungadala ezinye izimpawu ngaphezu kokuphefumula kanzima noma ukugwinya. Izimpawu zingavela kungakapheli amahora omjovo noma ngemuva kwamasonto ambalwa ukwelashwa. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo: ukuphelelwa amandla noma ubuthakathaka bemisipha emzimbeni wonke; umbono ophindwe kabili noma ofiphele; ukukhipha izinkophe noma ibunzi; ubunzima bokugwinya noma ukuphefumula; ukusha noma ukushintsha noma ukulahleka kwezwi; kunzima ukukhuluma noma ukusho amagama ngokucacile; noma ukungakwazi ukulawula ukuchama.

Udokotela wakho uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-onabotulinumtoxinA futhi isikhathi ngasinye lapho uthola ukwelashwa. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Umjovo we-OnabotulinumtoxinA (Botox, Botox Cosmetic) usetshenziselwa ukwelapha izimo eziningi.

InabotulinumtoxinA injection (Botox) is used to

• ukuqeda izimpawu ze-dystonia yomlomo wesibeletho (i-spasmodic torticollis; ukuqina okungalawuleki kwemisipha yentamo engadala izinhlungu zentamo nezikhundla zekhanda ezingajwayelekile) kubantu abaneminyaka engu-16 nangaphezulu;
• ukuqeda izimpawu ze-strabismus (inkinga yemisipha yamehlo edala ukuthi iso liphendukele ngaphakathi noma ngaphandle) kanye ne-blepharospasm (ukuqina okungalawuleki kwemisipha yejwabu leso okungadala ukucwayiza, ukuqumba, nokunyakaza okungavamile kwejwabu leso) kubantu abaneminyaka engu-12 ubudala nangaphezulu;
• ukuvimbela ukuphathwa yikhanda kubantu abadala kuneminyaka eyi-18 ubudala abane-migraine engapheli (ikhanda elibuhlungu, elibuhlungu elikhishwa ngezinye izikhathi elihambisana nesicanucanu nokuzwela kuzwakale noma ukukhanya) abanezinsuku eziyi-15 noma ngaphezulu inyanga ngayinye enekhanda elibuhlungu elithatha amahora ama-4 ngosuku noma ngaphezulu;
• welapha isinye esisebenza ngokweqile (isimo lapho imisipha yesinye ihlangana ngokungalawuleki futhi idale ukuchama kaningi, isidingo esiphuthumayo sokuchama, nokungakwazi ukulawula ukuchama) kubantu abaneminyaka engu-18 nangaphezulu lapho eminye imithi ingasebenzi kahle ngokwanele noma ingenakuthathwa;
• phatha ukungasebenzi (ukuvuza komchamo) kubantu abaneminyaka engu-18 nangaphezulu ngesinye esisebenza ngokweqile (isimo lapho imisipha yesinye ine-spasms engalawuleki) ebangelwa izinkinga zemizwa njengokulimala komgogodla noma i-multiple sclerosis (MS; isifo lapho izinzwa zingasebenzi kahle futhi abantu bangathola ubuthakathaka, ukuba ndikindiki, ukulahleka kokuxhumanisa kwemisipha, nezinkinga ngokubona, ukukhuluma, nokulawula isinye), abangakwazi ukwelashwa ngemithi yomlomo;
• phatha ukuqina (ukuqina kwemisipha nokuqina) kwezicubu ezingalweni nasemilenzeni kubantu abaneminyaka engu-2 nangaphezulu;
• phatha ukujuluka okunzima kwekhwapha kubantu abaneminyaka engu-18 nangaphezulu abangakwazi ukwelashwa ngemikhiqizo efakwe esikhunjeni;

futhi

InabotulinumtoxinA injection (Botox Cosmetic) is used to

• imigqa yokushelela ebushelelezi okwesikhashana (imibimbi phakathi kwamashiya) kubantu abadala abaneminyaka engu-18 nangaphezulu,
• imigqa yonyawo lwegwababa olubushelelezi okwesikhashana (imibimbi eduze kwekona elingaphandle leso) kubantu abadala abaneminyaka engu-18 nangaphezulu,
• kanye nokubhebhethekisa okwesikhashana imigqa yebunzi kubantu abadala abaneminyaka eyi-18 nangaphezulu.

Umjovo we-OnabotulinumtoxinUkilasi lemithi ebizwa ngama-neurotoxin. Lapho i-onabotulinumtoxinA ifakwa emsipheni, ivimba amasiginali wezinzwa abangela ukuqina okungalawuleki nokunyakaza kwemisipha. Lapho i-onabotulinumtoxinA ifakwa emgodleni wezithukuthuku, inciphisa umsebenzi wendlala ukunciphisa ukujuluka. Lapho i-onabotulinumtoxinA ifakwa esinyeni, inciphisa ukucindezela kwesinye futhi ivimbele amasiginali atshela uhlelo lwezinzwa ukuthi isinye sigcwele.

Umjovo we-Onabotulinumtoxin Umjovo uza njengempuphu ezohlanganiswa noketshezi bese ufakwa emsipheni, esikhunjeni, noma odongeni lwesinye ngudokotela. Udokotela wakho uzokhetha indawo engcono yokujova umuthi ukuze welaphe isimo sakho. Uma uthola i-onabotulinumtoxinA yokwelapha imigqa yokuswaca, imigqa yebunzi, imigqa yezinyawo zegwababa, i-dystonia yomlomo wesibeletho, i-blepharospasm, i-strabismus, ukuqina, ukungasebenzi komchamo, isinye esisebenza ngokweqile, noma i-migraine engapheli, ungathola imijovo eyengeziwe njalo ezinyangeni ezi-3 kuya kwezi-4, kuya nge isimo nokuthi imiphumela yokwelashwa ihlala isikhathi esingakanani. Uma uthola umjovo we-onabotulinumtoxinA ukwelapha ukujuluka okukhulu kwekhwapha, kungadingeka ukuthi uthole imijovo eyengeziwe kanye ezinyangeni eziyisithupha kuya kwezi-7 noma lapho izimpawu zakho zibuya.

Uma uthola umjovo we-onabotulinumtoxinA ukwelapha ukujuluka okunzima kwekhwapha, udokotela wakho mhlawumbe uzokwenza isivivinyo ukuthola izindawo ezidinga ukwelashwa. Udokotela wakho uzokutshela ukuthi ungalungiselela kanjani lokhu kuhlolwa. Mhlawumbe uzotshelwa ukuthi gunda izikhwama zakho zangaphansi futhi ungasebenzisi iziqobelo ezingabhaliswanga noma izidambisa amandla amahora angama-24 ngaphambi kokuhlolwa.

Uma uthola umjovo we-onabotulinumtoxinA ukwelapha ukungasebenzi kahle komchamo, udokotela wakho angakunika ama-antibiotic ongawathatha izinsuku eziyi-1-3 ngaphambi kokwelashwa kwakho, ngosuku lokwelashwa kwakho nangezinsuku ezi-1 ukuya kwezi-3 ngemuva kokwelashwa kwakho.

Udokotela wakho angashintsha umthamo wakho womjovo we-onabotulinumtoxinA ukuthola umthamo ozokusebenzela kangcono.

Udokotela wakho angasebenzisa ukhilimu we-anesthetic, noma iphakethe elibandayo, ukuqaqamba isikhumba sakho, noma amaconsi wamehlo ukuze abambe amehlo akho ngaphambi kokufaka i-onabotulinumtoxinA.

Uhlobo olulodwa noma uhlobo lwe-toxin ye-botulinum alunakufakwa esikhundleni salolunye.

Umjovo we-OnabotulinumtoxinUmjovo ungasiza ukulawula isimo sakho kepha ngeke uselaphe. Kungathatha izinsuku ezimbalwa noma kuze kube amasonto ambalwa ngaphambi kokuba uzwe inzuzo ephelele yomjovo we-onabotulinumtoxinA. Buza udokotela wakho lapho ungalindela ukubona ukuthuthuka, bese ushayela udokotela wakho uma izimpawu zakho zingathuthuki ngesikhathi esilindelekile.

Umjovo we-OnabotulinumtoxinA kwesinye isikhathi usetshenziselwa ukwelapha ezinye izimo lapho ukuqiniswa kwemisipha okungavamile kubangela ubuhlungu, ukunyakaza okungavamile, noma ezinye izimpawu. Inabotulinumtoxin Umjovo kwesinye isikhathi usetshenziselwa ukwelapha ukujuluka okweqile kwezandla, izinhlobo eziningi zemibimbi ebusweni, ukuthuthumela (ukuzamazama okungalawuleki kwengxenye yomzimba), nokuqhekeka kwe-anal (ukuhlukana noma ukudabuka esikhunjeni esiseduze nendawo engunxande) . Lo muthi kwesinye isikhathi usetshenziselwa ukuthuthukisa ikhono lokuhamba ezinganeni ezine-cerebral palsy (isimo esidala ubunzima ngokuhamba nangokulinganisela). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-onabotulinumtoxinA,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-onabotulinumtoxinA, abobotulinumtoxinA (Dysport), incobotulinumtoxinA (Xeomin), prabotulinumtoxinA-xvfs (Jeuveau), noma i-rimabotulinumtoxinB (Myobloc). Futhi, tshela udokotela wakho uma unalengozi kunoma imuphi omunye umuthi noma ezinye izithako zomjovo we-onabotulinumtoxinA. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antibiotic athile afana ne-amikacin, clindamycin (Cleocin), colistimethate (Coly-Mycin), gentamicin, kanamycin, lincomycin (Lincocin), neomycin, polymyxin, streptomycin, ne-tobramycin; ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); ama-antihistamine; i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); c heparin; imithi yokwaliwa yizifo, imikhuhlane, noma ukulala; ukuphumula kwemisipha; nama-platelet inhibitors afana ne-clopidogrel (Plavix). i-dipyridamole (i-Persantine, ku-Aggrenox), i-prasugrel (i-Effient), ne-ticlopidine (i-Ticlid). Phinda utshele udokotela wakho uma uthole imijovo yanoma yimuphi umkhiqizo we-botulinum toxin okubandakanya i-abobotulinumtoxinA (Dysport), incobotulinumtoxinA (Xeomin), prabotulinumtoxinA-xvfs (Jeuveau), noma i-rimabotulinumtoxinB (Myobloc) ezinyangeni ezine ezedlule. Udokotela wakho angadinga ukushintsha imithamo noma uhlelo lwemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-onabotulinumtoxinA, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma unesifo sokuvuvukala noma ezinye izimpawu zokutheleleka noma ubuthakathaka endaweni lapho i-onabotulinumtoxinA izofakwa khona. Udokotela wakho ngeke afake umuthi endaweni ethelelekile noma ebuthakathaka.
• uma uzobe uthola umjovo we-onabotulinumtoxinA ukwelapha ukungasebenzi kahle komchamo, tshela udokotela wakho uma une-urinary tract infection (UTI), engafaka izimpawu ezifana nobuhlungu noma ukushisa lapho uchama, ukuchama kaningi, noma umkhuhlane; noma uma ugcina umchamo (ukungakwazi ukukhipha isinye ngokugcwele) futhi ungasikhiphi njalo isinye sakho ngepayipi. Udokotela wakho ngeke akwelaphe ngomjovo we-onabotulinumtoxinA.
• Tshela udokotela wakho uma ngabe uke waba nemiphumela emibi kunoma yimuphi umkhiqizo we-botulinum toxin, noma ukuhlinzwa kwamehlo noma kobuso, uma ngabe unezinkinga zokopha noma wake waba nazo; ukuquleka; i-hyperthyroidism (isimo esenzeka lapho indlala yegilo ikhiqiza i-hormone yegilo eningi kakhulu), isifo sikashukela, noma amaphaphu noma isifo senhliziyo.
• uma uzobe uthola umjovo we-onabotulinumtoxinA ukwelapha imibimbi, udokotela wakho uzokuhlola ukuze abone ukuthi kungenzeka yini ukuthi lo muthi ungakusebenzela. Umjovo we-OnabotulinumtoxinUmjovo ungahle ungabhebhezeli imibimbi yakho noma ungadala ezinye izinkinga uma unamajwabu amehlo alengayo; unenkinga yokuphakamisa amashiya akho; noma olunye uguquko ngendlela ubuso bakho obuvame ukubukeka ngayo.
• uma uneminyaka engama-65 nangaphezulu futhi uzobe uthola umjovo we-onabotulinumtoxinA (Botox Cosmetic) ukuze ubhebhethekise okwesikhashana izinyawo zegwababa, imigqa yebunzi, noma imigqa yokuswaca, kufanele wazi ukuthi le ndlela yokwelashwa ayisebenzi nakubantu abadala asebekhulile uma kuqhathaniswa nabantu abadala abangaphansi kweminyaka engama-65 iminyaka yobudala.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-onabotulinumtoxinA, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-onabotulinumtoxinA.
• kufanele wazi ukuthi umjovo we-onabotulinumtoxinA ungadala ukulahleka kwamandla noma ubuthakathaka bemisipha emzimbeni wonke noma ukungaboni kahle. Uma unezinye zalezi zimpawu, ungashayeli imoto, sebenzisa imishini, noma wenze ezinye izinto eziyingozi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-OnabotulinumtoxinAngadala imiphumela emibi. Buza udokotela wakho ukuthi imiphi imiphumela emibi ongase uyithole, ngoba eminye imiphumela emibi ingavela kaningi engxenyeni yomzimba lapho uthole khona umjovo. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu, isisa, ukuvuvukala, ububomvu, ukopha, noma ukulinyazwa endaweni lapho uthole khona umjovo
• ukukhathala
• ubuhlungu bentamo
• ikhanda
• ukozela
• ubuhlungu bemisipha, ukuqina, ukuqina, ubuthakathaka, noma i-spasm
• ubuhlungu noma ukuqina ebusweni noma entanyeni
• umlomo owomile
• isicanucanu
• ukuqunjelwa
• ukukhathazeka
• ukujuluka okuvela kwezinye izitho zomzimba ngaphandle kwekhwapha
• ukukhwehlela, ukuthimula, umkhuhlane, ukuminyana kwamakhala, noma umphimbo obuhlungu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, nganoma yisiphi isikhathi phakathi kwamasonto ambalwa okuqala ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukubona kabili, ukufiphala, noma ukuncipha
• ukuvuvukala ijwabu leso
• izinguquko zombono (njengokuzwela okukhanyayo noma ukungaboni kahle)
• amehlo omile, acasukile noma abuhlungu
• ubunzima bokuhambisa ubuso
• isithuthwane
• ukushaya kwenhliziyo okungajwayelekile
• ubuhlungu besifuba
• ubuhlungu ezingalweni, emhlane, entanyeni, noma emhlathini
• ukuphelelwa umoya
• ukuquleka
• isiyezi
• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukukhwehlela, ukukhwehlela amafinyila, umkhuhlane noma ukubanda
• ukungakwazi ukukhipha isinye sakho uwedwa
• ubuhlungu noma ukushisa lapho uchama noma uchama kaningi
• igazi emchameni
• imfiva

Umjovo we-OnabotulinumtoxinA ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile ngokuvamile aziveli ngemuva kokuthola umjovo. Uma uthola i-onabotulinumtoxinA eningi kakhulu noma uma ugwinya umuthi, tshela udokotela wakho ngaso leso sikhathi futhi utshele udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo emasontweni ambalwa alandelayo:

• ubuthakathaka
• ubunzima bokuhambisa noma iyiphi ingxenye yomzimba wakho
• ukuphefumula kanzima
• ubunzima bokugwinya

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we-onabotulinumtoxinA.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Botox^®
• I-Botox^® Izimonyo

• I-BoNT-A
• I-BTA
• Uhlobo lwe-Botulinum Toxin