Inaliti yeLeucovorin

-Delile

• Ngaphambi kokuthola umjovo we-leucovorin,
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

Umjovo weLeucovorin usetshenziselwa ukuvikela imiphumela eyingozi ye-methotrexate (Rheumatrex, Trexall; imithi yokwelashwa ngamakhemikhali) lapho i-methotrexate isetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza. Umjovo weLeucovorin usetshenziselwa ukwelapha abantu abathole ukweqisa izidakamizwa kwe-methotrexate noma imithi efanayo. Umjovo weLeucovorin ubuye usetshenziselwe ukwelapha i-anemia (izinga eliphansi lamaseli abomvu egazi) okubangelwa amazinga aphansi e-folic acid emzimbeni. Umjovo weLeucovorin ubuye usetshenziswe ne-5-fluorouracil (umuthi wokwelapha ngamakhemikhali) ukwelapha umdlavuza ongumbala (umdlavuza oqala emathunjini amakhulu). Umjovo weLeucovorin usesigabeni semithi ebizwa nge-folic acid analogs. Iphatha abantu abathola i-methotrexate ngokuvikela amaseli anempilo emiphumeleni ye-methotrexate. Yelapha i-anemia ngokunikezela nge-folic acid edingekayo ekwakheni amangqamuzana abomvu egazi. Iphatha umdlavuza obala ngokweqile ngokwandisa imiphumela ye-5-fluorouracil.

Umjovo weLeucovorin uza njengesisombululo (uketshezi) nempuphu ezoxutshwa noketshezi futhi ifakwe ngomjovo (emthanjeni) noma emsipheni. Lapho umjovo we-leucovorin usetshenziselwa ukuvimbela imiphumela eyingozi ye-methotrexate noma ukwelapha ukweqisa izidakamizwa kwe-methotrexate noma umuthi ofanayo, uvame ukunikezwa njalo emahoreni ayisithupha kuze kube ukuhlolwa kwe-laboratory kukhombisa ukuthi awusadingeki. Lapho umjovo we-leucovorin usetshenziselwa ukwelapha i-anemia, uvame ukunikezwa kanye ngosuku. Lapho umjovo we-leucovorin usetshenziselwa ukwelapha umdlavuza obala ngokobulili, uvame ukunikezwa kanye ngosuku izinsuku ezinhlanu njengengxenye yokwelashwa okungaphindaphindwa kanye njalo emavikini amane kuya kwayi-5.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-leucovorin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-leucovorin, levoleucovorin, folic acid (Folicet, kumavithamini amaningi), noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imithi ethile yokuquleka efana ne-phenobarbital, phenytoin (Dilantin), ne-primidone (Mysoline); kanye ne-trimethoprim-sulfamethoxazole (Bactrim, Septra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma une-anemia (inani eliphansi lamaseli abomvu egazi) elibangelwa ukuntuleka kukavithamini B12 noma ukungakwazi ukuthola uvithamini B12. Udokotela wakho ngeke akunikeze umjovo we-leucovorin ukwelapha lolu hlobo lwe-anemia.
• Tshela udokotela wakho uma ngabe uke waba nokuqoqwa koketshezi esifubeni noma esiswini, umdlavuza osabalalele ebuchosheni bakho noma ohlelweni lwezinzwa, noma isifo sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-leucovorin, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isithuthwane
• ukuquleka
• isifo sohudo
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya

Umjovo weLeucovorin ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-leucovorin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Wellcovorin^® I.V.^¶

• isici se-citrovorum
• i-folinic acid
• I-5-formyl tetrahydrofolate

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.