Inaliti ye-Alemtuzumab (I-Chronic Lymphocytic Leukemia)

-Delile

• Ngaphambi kokuthola umjovo we-alemtuzumab,
• Umjovo we-Alemtuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Alemtuzumab (Campath) utholakala kuphela noma ngabe uhlelo olukhethekile lokusabalalisa olukhawulelwe (Campath Distribution Program). Ukuze uthole umjovo we-alemtuzumab (Campath) udokotela wakho kufanele abhaliswe nohlelo, futhi alandele izidingo. Uhlelo lweCampath Distribution luzothumela le mithi ngqo kudokotela, esibhedlela noma ekhemisi.

Umjovo we-Alemtuzumab ungadala ukwehla kwenani lamaseli egazi enziwe ngomnkantsha wakho. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukulimaza noma ukuphuma kwegazi okungavamile, izindawo ezincane ezibomvu noma ezibomvu emzimbeni wakho, isikhumba esiphaphathekile, ubuthakathaka, noma ukukhathala ngokweqile. Uzodinga ukuthatha izinyathelo ezengeziwe zokugwema ukulimala ngesikhathi sokwelashwa kwakho ngoba ungopha kakhulu kusuka ekusikeni okuncane noma kuma-scrapes. Geza amazinyo akho ngebhulashi elithambile, sebenzisa insingo kagesi uma uphuca, futhi ugweme ezemidlalo yokuxhumana neminye imisebenzi engalimaza.

Umjovo we-Alemtuzumab unganciphisa ikhono lakho lokulwa nokutheleleka futhi wandise ubungozi bokuthi uthole ukutheleleka okuyingozi noma okusongela impilo. Shayela udokotela wakho ngokushesha uma uba nezimpawu zokutheleleka ezinjengomkhuhlane, ukukhwehlela, umphimbo obuhlungu, noma isilonda esibomvu, ubovu obuzayo, noma esiphuza ukuphola.

Uzodinga ukuthatha izinyathelo zokuphepha ukunciphisa ingozi yokutheleleka ngesikhathi sokwelashwa kwakho ngomjovo we-alemtuzumab. Udokotela wakho uzokunika imithi ethile ukuvikela ukutheleleka. Uzophuza le mithi ngesikhathi ukwelashwa kwakho futhi okungenani izinyanga ezimbili ngemuva kokwelashwa kwakho. Thatha le mithi ngendlela eqondiswe ngayo. Kufanele futhi ugeze izandla zakho kaningi futhi ugweme abantu abanezifo ezithathelwanayo ezifana nokukhwehlela nemikhuhlane. Uma udinga noma yiluphi uhlobo lokumpontshelwa igazi ngesikhathi sokwelashwa kwakho ngomjovo we-alemtuzumab, kufanele uthole kuphela imikhiqizo yegazi enemisebe (imikhiqizo yegazi elashelwe ukuvikela ukusabela okuthile okungathí sina okungenzeka kubantu abenze buthaka amasosha omzimba).

Ungathola ukusabela okungathi sína noma okubulalayo ngenkathi uthola umthamo womjovo we-alemtuzumab. Uzothola umthamo ngamunye wemithi esikhungweni sezokwelapha, futhi udokotela wakho uzokuqapha ngokucophelela ngenkathi uthola lo muthi. Udokotela wakho uzokunika imithi ethile ukuvimbela lokhu kuphendula. Uzothatha le mithi kungekudala ngaphambi kokuthola umthamo ngamunye we-alemtuzumab. Udokotela wakho uzokuqala ngomthamo ophansi we-alemtuzumab futhi akhuphule kancane umthamo wakho ukuvumela umzimba wakho ukuthi ujwayele umuthi. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi sokumnika noma ngemuva kokumnika, tshela udokotela wakho ngokushesha: umkhuhlane; Ukugodola; isicanucanu; ukuhlanza; isifuba; ukuqubuka; ukulunywa; ubunzima bokuphefumula noma ukugwinya; ukuphefumula kancane; ukuqina komphimbo; ukuvuvukala kwamehlo, ubuso, umlomo, izindebe, ulimi noma umphimbo; ukushaqeka; isiyezi; ikhanda elikhanyayo; ukuquleka; ukushaya kwenhliziyo okusheshayo noma okungajwayelekile; noma ubuhlungu besifuba.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngesikhathi nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho kumjovo we-alemtuzumab.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-alemtuzumab.

Umjovo we-Alemtuzumab usetshenziselwa ukwelapha i-B-cell chronic lymphocytic leukemia (B-CLL; umdlavuza okhula kancane lapho izinhlobo eziningi kakhulu zamangqamuzana amhlophe egazi zihlangana emzimbeni). I-Alemtuzumab isekilasini lemithi ebizwa ngama-antibody monoclonal. Isebenza ngokwenza amasosha omzimba abulale amaseli omdlavuza.

I-Alemtuzumab iyatholakala futhi njengomjovo (i-Lemtrada) esetshenziselwa ukwelapha i-multiple sclerosis (isifo lapho izinzwa zingasebenzi kahle; ungahlangabezana nobuthakathaka, ukuba ndikindiki, ukulahlekelwa ukuhlangana kwemisipha nezinkinga ngombono, ukukhuluma, nokulawula isinye ). Le monograph inika kuphela imininingwane mayelana nomjovo we-alemtuzumab (Campath) we-B-CLL. Uma uthola i-alemtuzumab ye-multiple sclerosis, funda i-monograph enesihloko esithi Alemtuzumab Injection (Multiple Sclerosis).

Umjovo we-Alemtuzumab uza njengesisombululo (uketshezi) sokujova ngomjovo (emthanjeni) okungenani amahora ama-2 ngudokotela noma umhlengikazi esibhedlela noma ehhovisi lezokwelapha. Ekuqaleni, umjovo we-alemtuzumab uvame ukunikezwa ngemithamo ekhulayo kancane kancane yezinsuku ezi-3 kuye kwezi-7 ukuvumela umzimba ukuthi ujwayele umuthi. Lapho umzimba usujwayele umthamo odingekayo womjovo we-alemtuzumab, umuthi uvame ukunikezwa kathathu ngeviki ngezinsuku ezihlukile (imvamisa ngoMsombuluko, uLwesithathu nangoLwesihlanu) amasonto angafika kwayi-12.

Imithi oyithola ngaphambi komthamo ngamunye womjovo we-alemtuzumab ingahle ikwenze ulale. Cishe uzofuna ukucela ilungu lomndeni noma umngani ukuthi ahambe nawe lapho uthola imithi yakho futhi akubuyisele ekhaya ngemuva kwalokho.

Yize isimo sakho singathuthuka ngokushesha ngemuva kwamasonto amane kuya kwayisithupha ngemuva kokuqala ukwelashwa ngomjovo we-alemtuzumab, ukwelashwa kwakho kungahlala amasonto ayi-12. Udokotela wakho uzonquma ukuthi uyaqhubeka yini nokwelashwa kwakho futhi angalungisa umthamo wakho kuye ngokuthi umuthi usebenza kanjani kuwe nakwemiphumela emibi oyitholayo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-alemtuzumab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane emzimbeni we-alemtuzumab injection noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• utshele udokotela wakho uma ngabe uke waba nezimo zezempilo noma wake waba nazo.
• utshele udokotela wakho uma wena noma umlingani wakho ukhulelwe noma uhlela ukukhulelwa. Kuzofanele uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise izilawuli zokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nezinyanga ezi-3 ngemuva komthamo wakho wokugcina. Uma ukhulelwa ngesikhathi sokwelashwa kwakho ngomjovo we-alemtuzumab, shayela udokotela wakho ngokushesha. I-Alemtuzumab ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Ungancelisi ibele ngesikhathi sokwelashwa nge-alemtuzumab nezinyanga ezintathu ngemuva komthamo wokugcina.
• awunayo imigomo ebukhoma ngesikhathi noma ngemuva nje kokwelapha kwakho ngomjovo we-alemtuzumab ngaphandle kokukhuluma nodokotela wakho. Abesifazane abathola umjovo we-alemtuzumab ngenkathi bekhulelwe kufanele bakhulume nodokotela wezingane njengoba usana lwabo lungakwazi ukuthola imigomo ebukhoma isikhathi esithile.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesilisa nabesifazane. Khuluma nodokotela wakho ngezingozi zokuthola i-alemtuzumab.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-alemtuzumab.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Alemtuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• isifo sohudo
• ukulahlekelwa isifiso sokudla
• izilonda zomlomo
• ikhanda
• ukukhathazeka
• ubunzima bokulala noma ukulala
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ubuhlungu bemisipha

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukujula kolunye uhlangothi lobuso; ubuthakathaka obungazelelwe noma ukuba ndikindiki kwengalo noma umlenze, ikakhulukazi ohlangothini olulodwa lomzimba; noma kunzima ukukhuluma noma ukuqonda
• ukuvuvukala kwemilenze namaqakala, ukukhuluphala, ukukhathala. noma umchamo we-foamy (kungenzeka izinyanga noma iminyaka ngemuva komthamo wakho wokugcina)

I-Alemtuzumab ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuqinisa umphimbo
• ukuphefumula kanzima
• ukukhwehlela
• ukuncipha kokuchama
• ukulimaza noma ukopha okungavamile
• amabala abomvu noma ansomi esikhunjeni
• isikhumba esiphaphathekile
• ubuthakathaka
• ukukhathala ngokweqile
• umphimbo obuhlungu, umkhuhlane, amakhaza nezinye izimpawu zokutheleleka
• isicanucanu
• ukuhlanza
• isifuba
• ukuqubuka
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, umlomo, umphimbo, izindebe, noma ulimi
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ukuquleka
• ubuhlungu besifuba

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we-alemtuzumab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• ICampath^®