Ukujova kweLiraglutide

-Delile

• Ngaphambi kokusebenzisa umjovo we-liraglutide,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• Umjovo weLiraglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, yeka ukusebenzisa umjovo we-liraglutide bese ushayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo weLiraglutide ungakhuphula ubungozi bokuthi uzoba nezicubu zomgudu wegilo, kufaka phakathi i-medullary thyroid carcinoma (MTC; uhlobo lomdlavuza wegilo). Izilwane zaselabhorethri ezinikezwe i-liraglutide zaba nezimila, kepha akwaziwa ukuthi lo muthi wandisa ingozi yezimila kubantu. Tshela udokotela wakho ukuthi ngabe wena noma omunye emndenini wakho une-MTC noma i-Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; isimo esidala izicubu ezingxenyeni ezingaphezu kweyodwa emzimbeni). Uma kunjalo, udokotela wakho uzokutshela ukuthi ungasebenzisi umjovo we-liraglutide. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isigaxa noma ukuvuvukala entanyeni; ukushaqeka; ubunzima bokugwinya; noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-liraglutide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-liraglutide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-liraglutide.

Umjovo we-Liraglutide (i-Victoza) usetshenziselwa uhlelo lokudla nokuzivocavoca ukulawula amazinga kashukela egazini kubantu abadala nasezinganeni ezineminyaka eyi-10 nangaphezulu ngesifo sikashukela sohlobo 2 (isimo lapho umzimba ungasebenzisi i-insulin ngokujwayelekile ngakho-ke awukwazi ukulawula inani le ushukela egazini) lapho eminye imithi ingawalawulanga amazinga ngokwanele. Umjovo weLiraglutide (iVictoza) nawo usetshenziselwa ukunciphisa ubungozi bokuhlaselwa yisifo senhliziyo, ukushaywa unhlangothi, noma ukufa kubantu abadala abane-type 2 diabetes mellitus kanye nesifo senhliziyo nesomthambo wegazi. Umjovo weLiraglutide (iVictoza) awusetshenziswanga ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi khona i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma isifo sikashukela ketoacidosis (isimo esibi kakhulu esingakhula uma ushukela ophakeme wegazi ayelashwa) kubantu abadala. Umjovo weLiraglutide (Saxenda) usetshenziswa kanye nokwehliswa kokudla kwekhalori nohlelo lokuvivinya umzimba ukusiza abantu abadala abathile nezingane ezineminyaka engu-12 ubudala nangaphezulu abanesisindo esingamakhilogremu ayi-132 (60 kg) noma ngaphezulu futhi abakhuluphele noma abakhuluphele kakhulu futhi abanesisindo- Izinkinga ezihlobene nokwelashwa ukunciphisa isisindo nokugcina ungasitholi leso sisindo. Umjovo weLiraglutide (Saxenda) awusetshenziselwa ukwelapha uhlobo lwesifo sikashukela sohlobo 2. Umjovo weLiraglutide usesigabeni semithi ebizwa nge-incretin mimetics. Isebenza ngokusiza ama-pancreas ukukhipha inani elifanele le-insulin lapho amazinga kashukela egazi ephezulu. I-insulin isiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. Umjovo weLiraglutide ubambezela ukuphuma kwesisu futhi unganciphisa ukudla futhi kubangele ukuncipha.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

Umjovo we-Liraglutide uza njengesisombululo (uketshezi) epeni lokufaka elifakiwe ukuze ujove ngaphansi (ngaphansi kwesikhumba) esiswini sakho, ethangeni, noma engalweni ephezulu. Imvamisa ijovwa kanye ngosuku ngokudla noma ngaphandle kokudla. Sebenzisa umjovo we-liraglutide ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-liraglutide njengoba nje uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho kungenzeka akuqale ngomthamo ophansi womjovo we-liraglutide futhi akhuphule umthamo wakho ngemuva kweviki eli-1.

Umjovo weLiraglutide (Victoza) ulawula isifo sikashukela kepha awuselaphi. Qhubeka nokusebenzisa umjovo we-liraglutide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-liraglutide ngaphandle kokukhuluma nodokotela wakho.

Uma ungumuntu omdala osebenzisa umjovo we-liraglutide (Saxenda) wokwehlisa isisindo futhi ungalahli isisindo esithile ngemuva kwamasonto ayi-16 ekwelashwa, akunakwenzeka ukuthi uzozuza ngokusebenzisa lo muthi. Uma ungumntwana oneminyaka engu-12 ubudala nangaphezulu usebenzisa umjovo we-liraglutide (Saxenda) futhi ungalahlekelwa isisindo esithile ngemuva kwamasonto ayi-12 kumthamo wesondlo, akunakwenzeka ukuthi uzozuza ngokusebenzisa lo muthi. Udokotela wakho angakutshela ukuthi uyeke ukusebenzisa umjovo we-liraglutide (Saxenda) uma ungalahlekelwa isisindo esanele phakathi namasonto okuqala okwelashwa kwakho.

Uzodinga ukuthenga izinaliti ngokwehlukana. Buza udokotela wakho noma usokhemisi ukuthi iziphi izinhlobo zezinaliti ozodinga ukujova umuthi wakho. Qiniseka ukuthi ufunda futhi uqonde imiyalo yomkhiqizi yokujova i-liraglutide usebenzisa ipeni. Futhi qiniseka ukuthi uyazi ukuthi ungamisa kanjani ipeni elisha nini futhi nini, nokuthi kufanele wenzeni uma ubeka ipeni lakho. Uma ungaboni noma unamehlo angaboni kahle futhi ungakwazi ukufunda isibali sedosi esibayeni, ungasebenzisi leli peni ngaphandle kosizo. Cela udokotela wakho noma usokhemisi ukuthi akubonise ukuthi uyisebenzisa kanjani ipeni. Landela izinkomba ngokucophelela.

Hlala ubheka isisombululo sakho se-liraglutide ngaphambi kokusijova. Kufanele icace, ingenambala, futhi ingabi nezinhlayiya. Ungasebenzisi i-liraglutide uma inombala, inamafu, ijiyile, noma iqukethe izinhlayiya eziqinile, noma uma usuku lokuphelelwa yisikhathi ebhodleleni seludlulile.

Ungalokothi usebenzise izinaliti futhi ungalokothi wabelane ngezinaliti noma izibaya. Susa njalo inaliti ngemuva nje kokujova umthamo wakho. Lahla izinaliti esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-liraglutide,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-liraglutide, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-liraglutide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyiphuzayo ngomlomo ngoba i-liraglutide ingashintsha indlela umzimba wakho oyithatha ngayo le mithi. Phinda utshele udokotela wakho ngamanye ama-incretin mimetics afana ne-albiglutide (Tanzeum; ayisatholakali e-US) dulaglutide (Trulicity), exenatide (Bydureon, Byetta), lixisenatide (Adlyxin, eSoliqua), noma semaglutide (Ozempic); i-insulini; noma imithi yomlomo yesifo sikashukela, njenge-sulfonylureas, kufaka phakathi i-chlorpropamide, i-glimepiride (i-Amaryl, ku-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase), i-tolazamide ne-tolbutamide. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uphuza noma wake waphuza utshwala obuningi, uma uke waba nengcindezi, noma wacabanga noma wazama ukuzibulala, ushintsho ekuziphatheni, i-pancreatitis (ukuvuvukala kwamanyikwe); izinkinga ezinzima zesisu, kufaka phakathi i-gastroparesis (ukuhamba kancane kokudla kusuka esiswini kuya emathunjini amancane), izinkinga zokugaya ukudla; izinga eliphezulu lama-triglycerides (amafutha) egazini; ama-gallstones (amadiphozi aqinile akha ku-gallbladder); noma i-gallbladder, isifo sezinso noma sesibindi. Phinda utshele udokotela wakho uma usanda kuba nohudo, isicanucanu, noma ukuhlanza noma uma ungakwazi ukuphuza uketshezi ngomlomo, okungadala ukoma (ukulahlekelwa inani elikhulu lamanzi omzimba).
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwe akufanele usebenzise umjovo we-liraglutide (Saxenda) wokwehlisa isisindo. Uma ukhulelwa ngenkathi usebenzisa umjovo we-liraglutide (Victoza), shayela udokotela wakho.
• buza udokotela wakho ukuthi yini okufanele uyenze uma ugula, uba nesifo noma umkhuhlane, uba nengcindezi engajwayelekile, noma ulimele. Lezi zimo zingathinta ushukela wakho wegazi kanye nenani le-liraglutide ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo.

Jova umthamo ophuthelwe ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Musa ukujova umthamo ophindwe kabili ukwenzela okulahlekile. Uma ukhohlwa ukusebenzisa umjovo we-liraglutide izinsuku ezi-3 noma ngaphezulu, shayela udokotela wakho.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

Umjovo weLiraglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukuqunjelwa
• isilungulela
• ikhala eligobayo, ukuthimula, noma ukukhwehlela
• ukukhathala
• ubunzima bokuchama noma ubuhlungu noma ukushisa ekuchameni
• ukuqhuma kwesiza somjovo noma ubomvu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, yeka ukusebenzisa umjovo we-liraglutide bese ushayela udokotela wakho ngokushesha:

• ubuhlungu obuqhubekayo obuqala ngaphezulu kwesobunxele noma maphakathi nesisu kepha bungadlulela emuva
• ukucindezeleka okusha noma okuya kuba kubi
• ucabanga ngokuzilimaza noma ukuzibulala
• izinguquko ezingajwayelekile kumzwelo noma ekuziphatheni
• ukuhlanza
• isicanucanu
• isifo sohudo
• indle enombala wobumba
• amehlo aphuzi noma isikhumba
• inhliziyo ishaya ngamandla
• ukuquleka noma uzizwe unesiyezi
• ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya

Umjovo weLiraglutide ungadala eminye imiphumela emibi.Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ingena futhi ingafinyeleleki ezinganeni. Gcina kude nokukhanya nokushisa. Gcina izibaya ze-liraglutide ezingasetshenziswanga esiqandisini (36 ° F kuye ku-46 ° F [2 ° C kuye ku-8 ° C]) kodwa ungazibeki eduze kwento epholisa isiqandisi. Uma ipeni le-liraglutide selisetshenzisiwe, ligcine ekamelweni lokushisa (59 ° F kuye ku-86 ° F [15 ° C kuye ku-30 ​​° C]) noma esiqandisini. Ungafrizi. Ungasebenzisi i-liraglutide uma iqandisiwe noma ivezwe emazingeni okushisa angaphezu kwe-86 ° F (30 ° C). Gcina ikepisi esibayeni se-liraglutide lapho ingasetshenziswa.

Lapho usohambweni, qiniseka ukuthi ugcina izibaya ze-liraglutide zomile futhi kushisa okuphakathi kuka-59 ° F kuye ku-86 ° F (15 ° C kuye ku-30 ​​° C).

Bhala usuku owaqala ngalo ukusebenzisa ipeni le-liraglutide, bese ulilahla ngemuva kwezinsuku ezingama-30, noma ngabe kukhona isixazululo esisele esibayeni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu esinzima
• ukuhlanza okukhulu

Uma usebenzisa umjovo we-liraglutide (Victoza) ekwelapheni isifo sikashukela, ushukela wegazi kanye ne-glycosylated hemoglobin (HbA1c) kufanele ihlolwe njalo ukuthola impendulo yakho kulo muthi. Udokotela wakho uzokutshela nokuthi ungayihlola kanjani impendulo yakho kumjovo we-liraglutide ngokukala amazinga kashukela egazini lakho ekhaya. Landela lezi zinkomba ngokucophelela.

Uma usebenzisa umjovo we-liraglutide (Saxenda) wokulawula isisindo, izinga lenhliziyo yakho nesisindo sakho kuzohlolwa njalo ngesikhathi sokwelashwa.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Saxenda^®
• UVictoza^®
• I-Xultophy^® (njengomkhiqizo ohlanganisiwe oqukethe i-Insulin Degludec neLiraglutide)