I-Dextromethorphan neQuinidine

-Delile

• Ngaphambi kokuthatha i-dextromethorphan ne-quinidine,
• Ukuhlanganiswa kwe-dextromethorphan ne-quinidine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

Inhlanganisela ye-dextromethorphan ne-quinidine isetshenziselwa ukwelapha ukuthinteka kwe-pseudobulbar (i-PBA; isimo sokukhala noma ukuhleka okungazelelwe, okungalawulwa) kubantu abanezimo ezithile ezifana ne-amyotrophic lateral sclerosis (ALS, isifo sikaLou Gehrig; isimo lapho izinzwa ezilawula ukunyakaza kwemisipha ziyafa kancane, zenze imisipha inciphe futhi ibe buthakathaka) noma i-multiple sclerosis (isifo lapho izinzwa zingasebenzi kahle futhi iziguli zingathola ubuthakathaka, ukuba ndikindiki, ukulahlekelwa ukuhlangana kwemisipha nezinkinga ngombono, inkulumo, nokulawula isinye). UDextromethorphan usekilasini lemithi ebizwa ngama-central system agents agents. Indlela esebenza ngayo ebuchosheni ukwelapha i-PBA ayaziwa. I-Quinidine isekilasini lemithi ebizwa ngama-antiarrhythmics. Uma ihlanganiswe ne-dextromethorphan, i-quinidine isebenza ngokwandisa inani le-dextromethorphan emzimbeni.

Inhlanganisela ye-dextromethorphan ne-quinidine iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye ngosuku izinsuku eziyi-7. Ngemuva kwezinsuku eziyi-7, ithathwa njalo emahoreni ayi-12. Ungathathi imithamo engaphezu kwengu-2 esikhathini esingamahora angama-24. Qiniseka ukuthi uvumela cishe amahora ayi-12 phakathi komthamo ngamunye. Thatha i-dextromethorphan ne-quinidine cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha inhlanganisela ye-dextromethorphan ne-quinidine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angahlola ngezikhathi ezithile ukubona ukuthi lo muthi usadingeka yini ukulawula izimpawu zakho. Landela lezi zinkomba ngokucophelela.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-dextromethorphan ne-quinidine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-dextromethorphan, i-quinidine (i-Quinidex), i-quinine (i-Qualaquin), i-mefloquine (i-Lariam), noma imuphi omunye umuthi, noma iziphi izithako ezihlanganisiwe zamaphilisi we-dextromethorphan kanye ne-quinidine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-mefloquine (Lariam), i-pimozide (i-Orap), i-quinine (i-Qualaquin) thioridazine, noma omunye umkhiqizo oqukethe i-quinidine (i-Quinidex). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-dextromethorphan ne-quinidine uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imishanguzo yokulwa nokudangala okubandakanya i-clomipramine (Anafranil), i-desipramine (i-Doxepin, i-Sinequan), i-fluoxetine (i-Prozac, i-Sarafem), i-nefazodone, ne-paroxetine (i-Paxil, i-Pexeva); i-aprepitant (Hlela); i-clarithromycin (i-Biaxin, i-Prevpac); ukukhwehlela nemithi ebandayo equkethe i-dextromethorphan; i-cisapride; i-digoxin (i-Lanoxin, i-Digitek); i-erythromycin (i-EES E-Mycin, i-Erythrocin); i-fluconazole (iDiflucan); itraconazole (Sporanox); ketoconazole (Nizoral); imishanguzo ethile yegciwane lesandulela ngculaza (i-HIV) njenge-atazanavir (Reyataz), amprenavir (Agenerase), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), kanye ne-saquinavir (Invirase); imishanguzo yokushaya kwenhliziyo ngokungafani ne-amiodarone (Cordarone), i-diltiazem (i-Cardizem, i-Cartia, i-Tiazac, abanye), i-disopyramide (i-Norpace), i-dofetilide (i-Tikosyn), i-procainamide (i-Procanbid, i-Pronestyl), i-sotalol (i-Betapace), ne-verapamil (i-Calan, Covera, Isoptin, Verelan, eTarka); imithi yezinhlungu ezifana ne-codeine, i-hydrocodone (e-Hydrogesic, i-Lorcet, i-Lortab, i-Vicodin, i-Zydone, abanye), ne-methadone; moxifloxacin (Avelox); i-sparfloxacin (iZagam); kanye ne-teliththromycin (Ketek). Phinda utshele udokotela noma usokhemisi wakho uma uphuza le mithi elandelayo noma uyekile ukuyiphuza emasontweni amabili edlule: Ama-MAO inhibitors afaka i-isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl ), kanye ne-tranylcypromine (iParnate). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-dextromethorphan ne-quinidine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma uke waba nezimo ezilandelayo ngenkathi uthatha i-quinidine, i-quinine, noma i-mefloquine: ukwehla kwinani lamaseli egazi emnkantsheni wakho wethambo, i-lupus (isimo lapho umzimba uhlasela izicubu zawo ezidala ukulimala nokuvuvukala ), noma i-hepatitis (ukuvuvukala kwesibindi). Phinda utshele udokotela wakho uma ngabe uke waba nezigqi zenhliziyo ezingejwayelekile noma ukwehluleka kwenhliziyo. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i -xtromethorphan ne-quinidine.
• Tshela udokotela wakho uma uke waba ne-myasthenia gravis (ukuphazamiseka kwesistimu yezinzwa okubangela ukuba buthakathaka kwemisipha), umlando wokusetshenziswa kwezidakamizwa emgwaqweni noma ukusetshenziswa kabi kwezidakamizwa kadokotela, umfutho wegazi ophakeme, isifo sohlangothi, amazinga aphansi e-potassium noma i-magnesium ku igazi lakho, noma inhliziyo, izinso, noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha inhlanganisela ye-dextromethorphan ne-quinidine, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-dextromethorphan ne-quinidine.
• kufanele wazi ukuthi i-dextromethorphan ne-quinidine kungakwenza ube nesiyezi. Kubalulekile ukuthi uqaphele ukugwema ukuwa ngenkathi uthatha lo muthi.
• buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-dextromethorphan ne-quinidine. Utshwala bungenza imiphumela emibi yalo muthi ibe yimbi kakhulu.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esijwayelekile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile. Qiniseka ukuthi uvumela amahora ayi-12 phakathi kwamanani.

Ukuhlanganiswa kwe-dextromethorphan ne-quinidine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuhlanza
• igesi
• ubuhlungu besisu
• ukukhwehlela
• amehlo omile noma umlomo
• ubuthakathaka
• ukuphazamiseka kwemisipha
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukuchama kaningi, okubuhlungu, noma okunzima
• umchamo onamafu noma onuka kabi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• imfiva
• ukopha okungajwayelekile noma ukulinyazwa
• ubuhlungu bemisipha noma bamalunga
• ukuqubuka
• ukuvuvukala kobuso, umphimbo, ulimi, noma izindebe
• ama-lymph node avuvukile
• ukushaqeka
• ukuphefumula kanzima
• ubumhlophe
• ukuquleka
• ukushaya kwenhliziyo okusheshayo

Ukuhlanganiswa kwe-dextromethorphan ne-quinidine kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivaliwe ngokuqinile, futhi lapho izingane nezilwane ezifuywayo zingafinyeleli khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu
• ukuhlanza
• isifo sohudo
• isiyezi
• ikhanda
• kukhala ezindlebeni
• ukufiphala noma ukubona kabili
• ukudideka
• izinguquko ekushayeni kwenhliziyo
• ukuphefumula kanzima
• ukulahlekelwa ukwazi
• isithuthwane
• izinguquko ekucabangeni kwemisipha
• ukulahleka kokuxhumanisa
• injabulo engajwayelekile
• ukucabanga okungavamile

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-dextromethorphan ne-quinidine. Udokotela wakho angaphinde ahlele i-electrocardiogram (ECG; ukuhlolwa okulinganisa umsebenzi kagesi enhliziyweni) ngaphambi nangesikhathi sokwelashwa kwakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Nuedexta^®